Acefyl-125 60ml Syrup

Acefylline is a phosphodiesterase-4 (PDE-4) inhibitor. Its mechanism of action involves the selective inhibition of the PDE-4 enzyme. PDE-4 is an enzyme that breaks down cyclic adenosine monophosphate (cAMP) within cells. By inhibiting PDE-4, acefylline increases the levels of cAMP. Elevated cAMP levels lead to reduced inflammation and decreased production of inflammatory mediators like cytokines. This helps to diminish the inflammatory response in the airways and improves symptoms related to chronic respiratory conditions. Additionally, higher cAMP levels can lead to bronchodilation, which helps to open up the airways and improve airflow. Diphenhydramine is an antihistamine that primarily works as a competitive antagonist at histamine H1 receptors, effectively blocking the actions of histamine and alleviating allergy symptoms like itching and sneezing.

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Xanthine derivatives

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Syrup/Suspension

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This medication is used to treat:

• Bronchial asthma
• Chronic bronchitis
• Obstructive airway diseases
• Bronchoconstriction
• Coughing linked to respiratory issues

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Acefyl Syrup dosage recommendations are:

• Cough and respiratory conditions - 10-20 mL three times daily, Children (aged 2-6 years) - 5 mL three times daily, Children (aged 6-12 years) - 10 mL three times daily
• Chronic obstructive pulmonary disease (COPD) - 10-20 mL three times daily, Children (aged 6-12 years) - 10 mL three times daily

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Seek immediate medical attention. Contact poison control for guidance. Symptoms may include nausea and vomiting. Follow medical advice and monitor for adverse effects.

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Take the missed dose as soon as you remember, unless it’s almost time for the next dose. Do not double up on doses.

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Shake well before use. Measure the dose using a marked spoon or cup. Take as directed by your healthcare provider.

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Do not use Acefyl:

• If you are allergic to any of the ingredients.
• If you have severe liver or kidney disease.

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Unraveling the side effects lurking behind Acefyl 120ml Syrup are the following:

• Nausea
• Drowsiness
• Stomach discomfort
• Diarrhea
• Allergic reactions

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When using Acefyl Syrup, patients should be mindful of the following warnings and precautions:

• Avoid using the syrup if you have allergies or sensitivities to any of its components to prevent allergic reactions, such as rash or itching.
• Exercise caution if you have respiratory conditions like asthma or chronic obstructive pulmonary disease (COPD), as the syrup may impact respiratory function.
• Use the syrup carefully if you have liver or kidney disorders, as these conditions may affect the drug's metabolism and excretion.
• Be aware of potential interactions with other medications that affect mucus production or respiratory health. Consult your healthcare provider for personalized advice and to avoid adverse interactions.

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Drug interactions with Acefylline Piperazine include:

• Other xanthines (e.g., caffeine) (increased risk of side effects)
• Corticosteroids (increased risk of adverse effects)
• Beta-adrenergic agonists (increased risk of cardiovascular effects)
• Lithium (potential for increased lithium levels)
• CYP450 inducers (e.g., rifampin) (may reduce efficacy)
• CYP450 inhibitors (e.g., erythromycin) (may increase risk of toxicity)

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As of now, there are no known interactions between this drug and food. However, since comprehensive studies on food interactions may not be available, it is always a good idea to follow general dietary guidelines and consult your healthcare provider or pharmacist if you have any specific concerns or questions.

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For the proper storage of Acefyl-125 60ml Syrup, store it at a temperature between 15°C and 30°C in a cool, dry place, away from direct sunlight and moisture. Ensure the bottle is tightly capped to prevent contamination. For safety purposes, keep it out of reach of children and pets. Dispose of the product according to local regulations, avoiding flushing it or discarding it in regular trash.

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