Acefyl Cough 120ml Syrup

Acefylline is a phosphodiesterase-4 (PDE-4) inhibitor. Its mechanism of action involves the selective inhibition of the PDE-4 enzyme. PDE-4 is an enzyme that breaks down cyclic adenosine monophosphate (cAMP) within cells. By inhibiting PDE-4, acefylline increases the levels of cAMP. Elevated cAMP levels lead to reduced inflammation and decreased production of inflammatory mediators like cytokines. This helps to diminish the inflammatory response in the airways and improves symptoms related to chronic respiratory conditions. Additionally, higher cAMP levels can lead to bronchodilation, which helps to open up the airways and improve airflow. Diphenhydramine is an antihistamine that primarily works as a competitive antagonist at histamine H1 receptors, effectively blocking the actions of histamine and alleviating allergy symptoms like itching and sneezing.

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Acefylline Piperazine, Diphenhydramine

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Xanthine derivatives, Antihistamine

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Syrup/Suspension

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This medication is used to treat:

• Bronchial asthma
• Chronic bronchitis
• Obstructive airway diseases
• Bronchoconstriction
• Allergy symptoms
• Sneezing
• Runny nose
• Itching

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Acefyl Syrup dosage recommendations are:

• Cough and respiratory conditions - 10-20 mL three times daily, Children (aged 2-6 years) - 5 mL three times daily, Children (aged 6-12 years) - 10 mL three times daily
• Chronic obstructive pulmonary disease (COPD) - 10-20 mL three times daily, Children (aged 6-12 years) - 10 mL three times daily
• Allergic conditions - 10-20 mL three times daily, Children (aged 2-6 years) - 5 mL three times daily, Children (aged 6-12 years) - 10 mL three times daily

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Get emergency medical help right away. Contact poison control. Symptoms of overdose may include gastrointestinal distress. Do not induce vomiting unless directed by a healthcare professional.

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Take the missed dose as soon as you remember. If it’s almost time for the next dose, skip the missed dose. Do not double up.

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Shake well before use. Use the provided measuring device to take the correct dose. Follow the dosage instructions provided.

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Avoid using Acefyl:

• If you have a history of hypersensitivity to any ingredient.
• If you have severe gastrointestinal conditions.

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Unraveling the side effects lurking behind Acefyl 120ml Syrup are the following:

• Nausea
• Drowsiness
• Stomach discomfort
• Diarrhea
• Allergic reactions

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Patients should be aware of these precautions and warnings when using Acefyl Syrup:

• Individuals with allergies or sensitivities to any component of the syrup should avoid its use to prevent allergic reactions, such as rash or itching.
• Caution is advised for those with respiratory conditions like asthma or chronic obstructive pulmonary disease (COPD), as the syrup may affect respiratory function.
• Patients with liver or kidney disorders should use the syrup carefully, as these conditions can impact the drug's metabolism and excretion.
• Be mindful of potential interactions with other medications that affect mucus production or respiratory health, and consult a healthcare provider for personalized advice.
• This syrup may cause drowsiness; users should avoid activities requiring full mental alertness, such as driving or operating machinery, until they understand how the syrup affects them.
• Exercise caution with other central nervous system depressants and alcohol, as they can enhance drowsiness.
• Pregnant and breastfeeding women should consult their healthcare provider before using this syrup to ensure its safety.
• Always follow the product instructions and seek professional advice for safe and effective use.

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Drug interactions with Acefylline Piperazine, Diphenhydramine combination include:

• Other xanthines (e.g., caffeine) (increased risk of side effects)
• Corticosteroids (increased risk of adverse effects)
• Beta-adrenergic agonists (increased risk of cardiovascular effects)
• Lithium (potential for increased lithium levels)
• CYP450 inducers (e.g., rifampin) (may reduce efficacy)
• CYP450 inhibitors (e.g., erythromycin) (may increase risk of toxicity)
• Alcohol (enhanced sedation and impairment)
• Benzodiazepines (increased sedation)
• MAO inhibitors (risk of severe hypertension)
• Anticholinergic drugs (increased anticholinergic effects)
• Opioids (enhanced sedation and respiratory depression)
• Tricyclic antidepressants (increased anticholinergic effects and sedation)
• Other CNS depressants (enhanced drowsiness and impaired cognitive function)

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As of now, there are no known interactions between this drug and food. However, since comprehensive studies on food interactions may not be available, it is always a good idea to follow general dietary guidelines and consult your healthcare provider or pharmacist if you have any specific concerns or questions.

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For the proper storage of Acefyl-125 60ml Syrup, store it at a temperature between 15°C and 30°C in a cool, dry place, away from direct sunlight and moisture. Ensure the bottle is tightly capped to prevent contamination. For safety purposes, keep it out of reach of children and pets. Dispose of the product according to local regulations, avoiding flushing it or discarding it in regular trash.

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