Acenac (1.5% w/w) 20g Gel

Aceclofenac 0.015% gel exerts its analgesic and anti-inflammatory effects through its active ingredient, aceclofenac. This non-steroidal anti-inflammatory drug (NSAID) works by inhibiting the enzyme cyclooxygenase (COX), which plays a key role in the synthesis of prostaglandins. Prostaglandins are mediators of inflammation and pain, so by blocking their production, aceclofenac helps reduce inflammation and alleviate pain. When applied topically, aceclofenac is absorbed through the skin, allowing it to directly target the affected area and provide localized relief. This mechanism of action makes Aceclofenac gel a valuable option for managing localized pain and inflammation associated with conditions such as osteoarthritis and rheumatoid arthritis.

Aceclofenac 0.015

NSAID (Non-steroidal anti-inflammatory drug)

Gel

The following are the uses of Aceclofenac 0.015 Gel:

• Used for relieving pain and reducing inflammation in conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
• Used for treating acute pain due to injuries, sprains, strains, or post-operative pain.
• Used for managing pain and stiffness in muscles and joints, improving mobility.
• Used for reducing swelling and discomfort in conditions affecting the tendons, ligaments, and soft tissues.
• Used for providing localized pain relief in conditions such as backache, neck pain, or sports injuries.
• Used for easing pain and inflammation in certain types of arthritis, allowing better joint function.
• Used for offering temporary relief from pain and inflammation associated with minor musculoskeletal injuries.

Use twice a day on affected site. Do not rub vigorously. Apply a thin layer. Do not apply more than 4 times a day

In the case of an overdose of Aceclofenac 0.015 Gel, it is important to act promptly. If ingested, immediately rinse the mouth and drink a glass of water. Seek medical advice promptly, informing the healthcare professional about the product and the quantity involved. They will provide specific guidance based on the individual's health status and the extent of the overdose. Timely intervention can help manage any adverse effects effectively.

In the case of a missed dose of Aceclofenac 0.015 Gel, it is generally recommended to apply the gel as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not apply extra gel to make up for the missed dose. If you miss multiple doses, consult your healthcare provider for advice on how to adjust your dosing regimen to ensure the best therapeutic effect.

To apply Aceclofenac 0.015 Gel, gently squeeze a small amount of the gel onto your fingertips or directly onto the affected area and massage it into the skin, ensuring complete absorption, following the prescribed dosage and application frequency provided by your healthcare professional.

Following are the conditions when Aceclofenac 0.015 Gel should not be used:

• Do not use if you have a known allergy or hypersensitivity to Aceclofenac or any other ingredients in the gel.
• Avoid using the gel if you have a history of asthma or severe allergic reactions triggered by Aspirin or other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).
• Not recommended for individuals with active peptic ulcers or severe heart failure.
• Should not be applied to areas of broken skin, open wounds, infections, or severe skin conditions.
• Contraindicated in patients with severe kidney or liver impairment.
• Do not use the gel if you are in the third trimester of pregnancy or breastfeeding.
• Avoid using the gel if you have a history of gastrointestinal bleeding or perforation after taking NSAIDs.
• Not suitable for individuals with a rare hereditary condition of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.

The side effects of Aceclofenac 0.015 Gel may include:

• Skin redness or irritation at the application site
• Itching or rash
• Allergic reactions (skin redness, swelling, hives)
• Burning or stinging sensation
• Dry skin or peeling
• Increased sensitivity to sunlight
• Headache
• Nausea and dizziness

Following are the precautions and warnings for Aceclofenac 0.015 Gel:

• Avoid contact with eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water.
• Wash your hands thoroughly after applying the gel to avoid accidental transfer to sensitive areas.
• Do not apply the gel to open wounds, infected areas, or areas with skin conditions like eczema or dermatitis.
• Aceclofenac gel is for external use only. Do not ingest or apply to large areas of broken skin.
• Patients with known allergies to Aceclofenac or other NSAIDs should not use this gel.
• It is advised to avoid prolonged exposure to sunlight or UV rays while using Aceclofenac gel as it may increase photosensitivity.
• Consult a healthcare professional if you are pregnant, breastfeeding, or planning to become pregnant before using this medication.

Following are the drug interactions for Aceclofenac 0.015% Gel:

• Avoid using Aceclofenac with other topical medications, including other NSAID gels or creams, as it may increase skin irritation.
• Concomitant use with oral NSAIDs or other systemic medications with similar actions may increase the risk of adverse effects, such as gastrointestinal bleeding or kidney problems.
• Aceclofenac may reduce the antihypertensive effect of ACE inhibitors, so blood pressure monitoring is advised.
• Using Aceclofenac with diuretics can decrease their natriuretic effect and increase the risk of renal toxicity.
• It can increase the risk of bleeding when taken with anticoagulants or antiplatelet drugs.
• Lithium levels may be affected by Aceclofenac, so monitoring is recommended.
• Aceclofenac may enhance the activity of certain diabetes medications, increasing the risk of hypoglycemia.

Following are the food interactions to consider with Aceclofenac 0.015 Gel:

• Aceclofenac may cause stomach irritation, so it's best to avoid spicy and acidic foods that can aggravate this condition.
• Alcohol consumption should be minimized as it can increase the risk of gastrointestinal bleeding and liver-related side effects.
• Grapefruit and grapefruit juice should be avoided as they may interfere with the metabolism of Aceclofenac, potentially increasing its levels in the body.
• Avoid high-fat meals as they may delay the absorption of Aceclofenac, affecting its effectiveness.
• Dairy products like milk and cheese may decrease the absorption of Aceclofenac, so consider separating them by a few hours.
• Avoid caffeine-rich foods and beverages as they may enhance the stimulant effects of Aceclofenac, potentially causing restlessness and insomnia.
• If you have a history of kidney issues, consult your doctor about limiting foods high in potassium and phosphorus.
• Stay hydrated by drinking plenty of water, especially if you experience gastrointestinal side effects.

Aceclofenac 0.015% Gel should be stored in a cool, dry place, preferably at room temperature between 20-25°C (68-77°F). Keep the tube tightly sealed and protect it from direct exposure to sunlight or moisture. Avoid storing it in the refrigerator as low temperatures may alter the gel's consistency. Always check the expiration date before use and discard any expired or unused gel. When disposing of the medication, do not pour it down the drain or flush it into the sewage system. Instead, follow local guidelines for pharmaceutical waste disposal or consult your pharmacist for safe disposal practices. Keep the gel away from children and pets to prevent accidental ingestion or misuse.

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Following are the quick tips for Aceclofenac 0.015% Gel:

• Clean and dry the affected skin area before applying the gel.
• Apply a thin layer of gel and gently massage it into the skin.
• Wash your hands after application to avoid accidental contact with eyes or sensitive areas.
• Avoid applying the gel on broken or irritated skin.
• Do not cover the treated area with bandages or tight clothing, allow it to breathe.
• Store the gel in a cool, dry place, away from direct sunlight.
• Consult your doctor if symptoms persist or worsen despite using the gel as directed.