ACHFREE GEL 25G

Glucosamine gel works by delivering glucosamine, a naturally occurring compound, directly to the affected joint areas. When applied topically, the gel allows glucosamine to penetrate the skin and reach the underlying tissues. Its mechanism of action involves supporting the synthesis of proteoglycans, key components of cartilage. Glucosamine stimulates the production of these molecules, which help attract and bind water into the cartilage matrix, thereby enhancing its lubrication, elasticity, and overall joint health. By promoting the formation of proteoglycans, glucosamine gel aids in maintaining joint flexibility, reducing inflammation, and potentially slowing down the breakdown of cartilage in conditions like osteoarthritis.

Glucosamine

Topical analgesic.

Gel

The following are the uses of Glucosamine Gel:

• Used for reducing joint pain and inflammation, especially in conditions like osteoarthritis.
• Used for improving joint mobility and flexibility, aiding in the recovery of joint injuries.
• Used for supporting cartilage health by providing the building blocks for cartilage repair.
• Used for managing symptoms of joint degeneration, helping to slow down the progression of joint damage.
• Used for enhancing joint lubrication, reducing friction and improving joint comfort.
• Used for alleviating stiffness in joints, particularly after periods of inactivity or in cold weather.
• Used for promoting overall joint health and function, contributing to long-term joint maintenance.

In the case of an overdose of Glucosamine Gel, it is important to note that while the gel is generally considered safe, excessive application may lead to skin irritation. Symptoms of an overdose could include increased skin sensitivity, redness, or itching at the application site. If you suspect an overdose, wash the affected area with mild soap and water, and consult a healthcare professional for further guidance if symptoms persist or worsen.

In the case of a missed dose of Glucosamine Gel, it is generally advised to apply the gel as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not apply extra gel to make up for the missed dose, as this may lead to skin irritation. It's important to maintain a consistent application routine, but if you have any concerns or frequently miss doses, consult your healthcare provider for guidance on how to adjust your regimen.

To use Glucosamine Gel, apply a thin layer to the affected area of the skin and gently massage it until the gel is absorbed, typically two to three times a day or as directed by your healthcare professional.

Here are the conditions and situations when Glucosamine Gel should not be used:

• Avoid using if you have a known allergy or sensitivity to glucosamine, shellfish, or any other ingredients in the gel formulation.
• Do not use if you are pregnant or breastfeeding, as the safety of glucosamine in these situations has not been well established.
• Not recommended for individuals with diabetes, as glucosamine may affect blood sugar levels.
• Should not be applied to open wounds, infected areas, or severely damaged skin.
• Avoid using on skin with severe skin conditions like eczema, psoriasis, or severe dermatitis.
• Not suitable for those with a history of asthma, as some glucosamine products may contain shellfish derivatives which can trigger allergic reactions.
• Do not use in combination with certain medications like blood thinners without medical advice, as it may affect their effectiveness.

The side effects of Glucosamine Gel may include:

• Skin irritation at the application site
• Redness or itching
• Dryness or peeling of the skin
• Mild rash or hives
• Increased sensitivity to sunlight
• Mild swelling or bruising
• Joint stiffness (temporary)
• Gastrointestinal discomfort (rare)

Following are the precautions and warnings for Glucosamine Gel:

• Avoid contact with eyes, nose, and mouth. In case of accidental contact, rinse thoroughly with water.
• For external use only. Do not ingest or swallow the gel.
• Wash your hands thoroughly before and after applying the gel to avoid contamination.
• Do not apply to open wounds, cuts, or irritated skin.
• Discontinue use and consult a healthcare professional if you experience any skin irritation, redness, or allergic reactions.
• Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
• Consult a doctor if you are pregnant, breastfeeding, or have any underlying medical conditions before using this gel.

Following are the drug interactions for Glucosamine Gel:

• Glucosamine may decrease the effectiveness of Acarbose, a medication used to treat type 2 diabetes, by competing for the same transporters.
• The gel may interact with anticoagulant medications like Warfarin, potentially affecting blood clotting and requiring close monitoring of INR values.
• Using Glucosamine with other topical agents or skin products may result in altered absorption or increased skin irritation.
• Caution is advised when using Glucosamine with nonsteroidal anti-inflammatory drugs (NSAIDs), as it may increase the risk of gastrointestinal bleeding.
• It can potentially reduce the effectiveness of certain antibiotics, such as Tetracyclines, by forming complexes that hinder absorption.
• Glucosamine might have additive effects when used with other dietary supplements like chondroitin, requiring monitoring for potential adverse reactions.
• Patients taking medications for diabetes, especially insulin, should be monitored closely as Glucosamine may affect blood sugar levels.

Following are the food interactions for Glucosamine Gel:

• Alcohol may cause increased risk of gastrointestinal side effects, so it is advisable to avoid or limit alcohol consumption while using this medication.
• Avoid grapefruit and grapefruit juice as they can interfere with the absorption and metabolism of many medications, potentially altering their effectiveness.
• High-sodium foods should be consumed in moderation as glucosamine may increase sodium levels in the body.
• There are no specific food restrictions, but maintaining a balanced diet is recommended for overall health.
• Inform your healthcare provider if you have any dietary restrictions or preferences to ensure the best treatment plan.
• Stay hydrated and drink plenty of water, especially if you experience dryness or irritation after applying the gel.
• Certain herbal supplements like Ginkgo Biloba or garlic supplements might interact, so consult your pharmacist or doctor before taking any supplements.

Glucosamine Gel should be stored in a cool, dry area at room temperature, protected from direct sunlight and moisture. Ensure the gel remains sealed in its original container to maintain its integrity and prevent contamination. Avoid extreme temperatures by not storing it in hot or humid environments, like bathrooms or near heat sources, as this can impact the gel's effectiveness. Dispose of any unused or expired gel responsibly; do not flush or pour it down the drain. Consult a pharmacist or healthcare professional for guidance on proper disposal methods, and keep the gel out of children's reach to prevent accidental contact or ingestion.

Following are the quick tips for Glucosamine Gel:

• Apply a thin layer of the gel on affected joints or as directed by your healthcare professional.
• Ensure the area is clean and dry before application.
• Gently massage the gel into the skin until it is fully absorbed.
• Wash your hands after application to avoid accidental contact with eyes or mouth.
• Use consistently as prescribed for best results, typically 2-3 times daily.
• Avoid using on open wounds or broken skin.
• Store the gel at room temperature, away from direct sunlight.