ACITEC 25MG TAB

Acitretin is a retinoid medication primarily used for its effects on skin cells. Its mechanism of action involves binding to specific retinoic acid receptors (RARs) in the cell nucleus. By activating these receptors, acitretin regulates gene expression and influences cellular processes. It modulates cellular differentiation, proliferation, and keratinization in the epidermis, promoting the normalization of keratinocyte behavior. This action helps to correct abnormal skin cell growth and differentiation, making it effective in treating various skin conditions, particularly those characterized by excessive skin cell proliferation and inflammation.

Acitretin 25mg

Retinoid derivative

Tablet

The following are the uses of Acitretin 25mg Tablet:

• Used for treating severe psoriasis, providing relief from scaly and itchy skin.
• Used to effectively manage psoriasis symptoms, allowing for clearer and healthier skin.
• Used to slow down the growth of skin cells, reducing the severity of psoriasis.
• Used in severe cases of psoriasis where other treatments have been ineffective.
• Used to improve skin condition by reducing redness, inflammation, and skin thickening.
• Used to provide long-term control of psoriasis, often in combination with other therapies.
• Used to treat a rare condition called pityriasis rubra pilaris, which causes similar symptoms to psoriasis.
• Used under strict medical supervision due to potential side effects and interactions.

In the case of an overdose of Acitretin 25mg Tablets, individuals may experience symptoms such as headache, skin peeling, and dry mouth. Excessive intake can lead to severe health consequences, including liver damage and bone abnormalities. Prompt action is necessary if an overdose is suspected, including contacting a healthcare professional or poison control center for guidance. It is important to provide accurate information about the quantity ingested to facilitate appropriate treatment and minimize potential risks associated with overdosing on this medication.

In the case of a missed dose of Acitretin 25mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication or adjust the dosage accordingly. It is recommended to maintain a consistent dosing routine to ensure the medication's effectiveness.

To take Acitretin 25mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the exact dosage instructions provided by your healthcare professional, typically once daily or as directed by your doctor.

Following are the conditions/situations when Acitretin 25mg Tablet should not be used:

• Strictly contraindicated in women who are pregnant or planning to become pregnant.
• Should not be used by breastfeeding mothers as it may harm the nursing infant.
• Individuals with a known allergy or sensitivity to Acitretin or any of its components should avoid this medication.
• Not recommended for patients with severe liver or kidney disease, as it can worsen these conditions.
• Avoid using this medication if you have uncontrolled high cholesterol or triglyceride levels.
• Do not use if you have a history of severe depression or other mental health disorders.
• Contraindicated in individuals with vitamin A toxicity or a history of excessive vitamin A intake.
• Not suitable for children and adolescents under 18 years of age.

The side effects of Acitretin 25mg Tablet may include:

• Dry skin, itching, and skin peeling
• Hair loss or thinning
• Brittle nails
• Joint and muscle pain
• Lip inflammation and dryness
• Increased sensitivity to sunlight
• Changes in liver function (liver enzymes may increase)
• Elevated cholesterol and triglyceride levels in the blood

Following are the precautions and warnings for Acitretin 25mg Tablet:

• Not recommended for women who are pregnant or planning to become pregnant as it may cause severe birth defects.
• Women of childbearing age should undergo pregnancy tests before, during, and after treatment to ensure they are not pregnant.
• Effective contraception must be used during and for a certain period after treatment to prevent pregnancy.
• Avoid breastfeeding while on this medication as it may pass into breast milk and harm the baby.
• Blood tests are required to monitor liver function, blood lipids, and blood sugar levels during treatment.
• May cause sensitivity to sunlight; limit sun exposure and use protective measures when outdoors.
• Not suitable for individuals with severe kidney or liver disease.
• Discontinue the medication and seek medical attention if any severe side effects occur.

Following are the drug interactions for Acitretin 25mg Tablet:

• Avoid combining with other retinoids, as it may lead to increased risk of side effects.
• Tetracycline antibiotics should not be used simultaneously due to potential drug interaction risks.
• The effectiveness of hormonal contraceptives may be reduced, so alternative birth control methods are recommended.
• Vitamin A supplements should be avoided as they can enhance Acitretin's side effects.
• Alcohol consumption should be minimized as it can increase the risk of liver toxicity.
• Acitretin may interact with certain cholesterol-lowering medications, requiring close monitoring.
• Blood tests are advised when taken with methotrexate to prevent potential toxicity.

Following are the food interactions for Acitretin 25mg Tablet:

• Avoid excessive Vitamin A-rich foods like liver, liver products, and supplements containing Vitamin A as Acitretin is a Vitamin A derivative, and excessive Vitamin A can lead to toxicity.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Acitretin, potentially increasing its levels in the body and the risk of side effects.
• Alcohol can increase the risk of liver-related side effects and is best avoided or consumed in moderation while on Acitretin.
• Dairy products with high-fat content might interfere with Acitretin absorption; consider consuming low-fat dairy alternatives.
• Foods rich in Omega-3 fatty acids, like fish oil supplements, might increase the risk of bleeding when taken with Acitretin.
• Avoid high-protein diets, as they may affect the effectiveness of Acitretin.
• Always stay hydrated and maintain a balanced diet rich in fruits and vegetables for optimal health while on this medication.

Acitretin 25mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area, away from direct sunlight, moisture, and heat. It is crucial to keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to environmental factors. Do not store them in the bathroom or kitchen, as these areas may have fluctuating temperatures and humidity levels. Regularly check the expiration date on the packaging, and dispose of any expired or unused tablets promptly. When disposing of the medication, do not flush it down the toilet or pour it into drainage systems. Instead, follow local guidelines or consult a pharmacist for safe disposal options. Ensure that the medication is kept out of the reach of children and pets to prevent accidental ingestion.

Following are the quick tips for Acitretin 25mg Tablet:

• Ensure you take the tablet as directed by your doctor for the best results.
• Maintain a consistent schedule by taking it at the same time daily.
• Swallow the tablet whole with a full glass of water; do not crush or chew.
• Avoid consuming alcohol while on this medication.
• Inform your doctor about all medications you are taking to prevent interactions.
• Do not donate blood while on this medication and for at least 3 years after stopping it.
• Regularly monitor your blood lipid levels as directed by your healthcare provider.