Actifed DM? Cough Syp 60 ml

Pseudoephedrine and dextromethorphan are the active ingredients in the syrup/suspension. Pseudoephedrine primarily acts as a sympathomimetic amine, stimulating alpha-adrenergic receptors in the respiratory tract, leading to vasoconstriction and reduced congestion. This action helps to shrink swollen blood vessels in the nose and throat, providing relief from nasal congestion. Dextromethorphan, on the other hand, is a central-acting cough suppressant that acts on the brain's cough center to reduce the urge to cough. It binds to sigma-1 receptors and acts as an N-methyl-D-aspartate (NMDA) receptor antagonist, which helps suppress the cough reflex without affecting the respiratory tract directly.

Nasal decongestant, Antitussive

Suspension

The following are the uses of Pseudoephedrine, dextromethorphan Syrup/Suspension:

• Used for temporarily relieving symptoms of the common cold, such as nasal congestion, sinus pressure, and runny nose.
• Used for reducing inflammation and swelling in the nasal passages and sinuses.
• Used for treating congestion and promoting easier breathing.
• Used for suppressing coughs caused by minor throat and airway irritation.
• Used for providing temporary relief from coughing fits and soothing the throat.
• Used for managing symptoms of upper respiratory tract infections.
• Used for improving overall respiratory comfort during illness.

In the case of an overdose of Pseudoephedrine and dextromethorphan syrup/suspension, individuals may experience severe symptoms. These can include rapid heartbeat, dizziness, severe headache, and even hallucinations. Gastrointestinal issues such as nausea, vomiting, and abdominal pain are also common. It is crucial to seek medical assistance promptly, as healthcare professionals can provide the necessary treatment and support to manage the overdose effectively.

In the case of a missed dose of Pseudoephedrine and dextromethorphan Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one, as this may increase the risk of side effects. Consult your healthcare provider if you have any concerns or questions regarding missed doses.

To use Pseudoephedrine and dextromethorphan syrup/suspension, shake the bottle well, measure the prescribed dose with the provided dosing cup or syringe, and administer the medication orally, following the dosage instructions provided by your healthcare professional, typically taken every 4 to 6 hours as needed for congestion and cough relief.

Here are the situations or conditions when Pseudoephedrine, dextromethorphan Syrup/Suspension should not be used:

• Avoid using this medication if you have an allergy to Pseudoephedrine, dextromethorphan, or any other decongestants or antitussives.
• Do not take if you have taken a monoamine oxidase inhibitor (MAOI) in the last 14 days.
• Contraindicated in patients with narrow-angle glaucoma.
• Not suitable for individuals with severe high blood pressure or cardiovascular disease.
• Should not be used if you have difficulty urinating due to an enlarged prostate gland.
• Avoid using this medication if you have a severe lung disease such as chronic obstructive pulmonary disease (COPD) or severe asthma.
• Do not give this medication to children under 4 years old.
• Contraindicated in patients with a history of seizures or conditions that increase the risk of seizures.

The side effects of Pseudoephedrine and dextromethorphan Syrup/Suspension may include:

• Nervousness or restlessness
• Dizziness or lightheadedness
• Nausea and vomiting
• Dry mouth
• Headache
• Increased heart rate or palpitations
• Difficulty sleeping (insomnia)
• Mild skin rash or hives

Following are the precautions and warnings for Pseudoephedrine, dextromethorphan Syrup/Suspension:

• Avoid using this medication if you have a known allergy to Pseudoephedrine or dextromethorphan, or any other ingredients in the syrup/suspension.
• Patients with high blood pressure, heart disease, diabetes, thyroid problems, or an enlarged prostate should use with caution and under medical supervision.
• This medication may cause dizziness and drowsiness, so avoid driving or operating heavy machinery until you know how it affects you.
• Do not consume alcohol while taking this medication as it may increase the risk of side effects.
• If you are taking any other medications, including over-the-counter drugs, inform your doctor or pharmacist to ensure there are no interactions.
• Pregnant and breastfeeding women should consult their healthcare provider before using this medication, as it may have potential risks to the fetus or infant.
• Keep this medication out of reach of children. In case of accidental overdose, seek immediate medical attention.

Following are the drug interactions for Pseudoephedrine, dextromethorphan Syrup/Suspension:

• Monoamine oxidase inhibitors (MAOIs) should not be used concurrently, as they can cause severe hypertension and other cardiovascular effects.
• Use with other sympathomimetic agents (e.g., epinephrine, norepinephrine) may lead to increased cardiovascular side effects.
• Antihypertensive medications can be less effective when taken with pseudoephedrine.
• Dextromethorphan may enhance the effects of CNS depressants like benzodiazepines and alcohol, leading to increased sedation.
• Serotonergic drugs, including SSRIs and SNRIs, may increase the risk of serotonin syndrome when combined with dextromethorphan.
• Anticonvulsant levels may be altered by dextromethorphan, potentially requiring dosage adjustments.
• Drugs that affect liver metabolism, such as certain antifungal agents, can influence dextromethorphan's effects.

Following are the food interactions for Pseudoephedrine, dextromethorphan Syrup/Suspension:

• Avoid consuming grapefruit and grapefruit juice as they can interfere with the metabolism of dextromethorphan, potentially leading to increased side effects.
• Alcohol consumption should be avoided as it can enhance the drowsiness and dizziness caused by dextromethorphan.
• Caffeine-containing beverages like coffee and energy drinks may counteract the sedating effects of dextromethorphan, making it less effective.
• High-fat meals can slow down the absorption of dextromethorphan, possibly reducing its effectiveness.
• Spicy foods can sometimes irritate the throat and worsen cough symptoms, especially when combined with dextromethorphan.
• Consuming excessive amounts of sugar, often found in cough syrups, can lead to dental issues and contribute to calorie intake.
• Avoid consuming foods or drinks that are extremely hot or cold, as they can irritate the throat and potentially affect the absorption of the medication.
• It's generally recommended to take the medication with a full glass of water to ensure proper absorption and reduce the risk of stomach irritation.

Pseudoephedrine and dextromethorphan syrup/suspension should be stored in a secure and controlled environment, preferably in a locked cabinet or a designated medication storage area, ensuring it is inaccessible to unauthorized individuals. It is crucial to keep the medication in its original packaging, tightly sealed, and protected from light and moisture. When disposing of unused or expired syrup, follow local guidelines for pharmaceutical waste disposal, as flushing or pouring it down the drain can be harmful to the environment. Contact your pharmacist or local waste management authorities for specific instructions on proper disposal methods. Responsible storage and disposal practices are vital to prevent misuse and protect public health and safety.

Following are the quick tips for Pseudoephedrine, dextromethorphan Syrup/Suspension:

• Consult a healthcare professional for dosage instructions, especially for children under 12 years old.
• Measure the dose accurately using a measuring cup or spoon.
• Take the syrup as directed, usually every 4-6 hours, but not more than directed.
• Avoid taking it with other medications containing the same active ingredients.
• Do not increase the dose or frequency without medical advice.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Dispose of any unused or expired medication safely.