ACTIFED DM SYP 120ML

Pseudoephedrine is a sympathomimetic amine that acts as a vasoconstrictor, reducing congestion by narrowing the blood vessels in the nasal passages. Dextromethorphan suppresses the cough reflex by acting centrally in the brainstem to elevate the threshold for coughing. Triprolidine, a first-generation antihistamine, blocks histamine H1 receptors, thereby relieving allergic symptoms such as runny nose, sneezing, and itching.

Nasal decongestant, Antitussive, Antihistamine.

Suspension

The following are the uses of Pseudoephedrine, dextromethorphan, Triprolidine Syrup/Suspension:

• Used for temporarily relieving symptoms of the common cold, such as a runny nose, sneezing, and congestion.
• Used to provide relief from cough and chest congestion caused by the common cold or flu.
• Used to relieve symptoms of allergic rhinitis, including runny nose, sneezing, and itching.
• Effective in reducing inflammation and swelling in the nasal passages.
• Helps to dry up nasal discharge and reduce post-nasal drip.
• Can be used to temporarily reduce redness and swelling in the eyes caused by allergies.
• Provides temporary relief from sinus congestion and pressure.

In the case of an overdose of Pseudoephedrine, dextromethorphan, and Triprolidine Syrup/Suspension, symptoms may include rapid heartbeat, dizziness, severe drowsiness, and confusion. Nausea, vomiting, and diarrhea are also common. Immediate medical attention is necessary, and emergency services should be contacted. Treatment involves managing symptoms and providing supportive care. It is crucial to seek professional help to ensure the best outcome and prevent potential complications.

In the case of a missed dose of Pseudoephedrine, dextromethorphan, and Triprolidine Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. For children, it is crucial to consult a doctor or pharmacist to determine the appropriate course of action for a missed dose.

To administer Pseudoephedrine, dextromethorphan, and Triprolidine Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring device, and take it orally as directed by your healthcare provider, typically every 4 to 6 hours, with or without food, ensuring you follow the dosage instructions for your age and condition.

Here are the conditions or situations when Pseudoephedrine, dextromethorphan, Triprolidine Syrup/Suspension should not be used:

• Avoid in individuals with a known allergy or hypersensitivity to Pseudoephedrine, dextromethorphan, Triprolidine, or any of the excipients in the syrup/suspension.
• Not suitable for patients with narrow-angle glaucoma.
• Contraindicated in patients with severe high blood pressure, cardiovascular disease, or those who have recently had a heart attack.
• Should not be used in individuals with difficulty urinating due to an enlarged prostate.
• Avoid in patients with severe liver or kidney disease.
• Not recommended for children under 2 years of age.
• Should not be combined with certain medications, such as Monoamine Oxidase Inhibitors (MAOIs) or other cold and cough medications.
• Contraindicated in patients with a history of seizures or those who are currently taking medications that lower the seizure threshold.

The side effects of Pseudoephedrine, dextromethorphan, and Triprolidine Syrup/Suspension may include:

• Drowsiness or sedation
• Dry mouth
• Constipation
• Blurred vision
• Dizziness or lightheadedness
• Nausea and vomiting
• Restlessness or excitability (especially in children)
• Increased heart rate or blood pressure

Following are the precautions and warnings for Pseudoephedrine, dextromethorphan, Triprolidine Syrup/Suspension:

• Do not use if you have a known allergy to any of the ingredients, including pseudoephedrine, dextromethorphan, or triprolidine.
• This medication may cause drowsiness or dizziness; avoid driving or operating machinery until you know how it affects you.
• Alcohol consumption should be avoided as it may intensify the medication's side effects.
• Patients with heart conditions, high blood pressure, diabetes, thyroid problems, or prostate enlargement should use this medication with caution and under medical supervision.
• Not recommended for use in children under 4 years old without medical advice.
• Consult a doctor before use if you are pregnant, planning to become pregnant, or breastfeeding.
• If symptoms persist or worsen, or if new symptoms appear, discontinue use and seek medical advice immediately.

Following are the drug interactions for Pseudoephedrine, dextromethorphan, Triprolidine Syrup/Suspension:

• Monoamine oxidase inhibitors (MAOIs) should be avoided, as they can cause a severe increase in blood pressure.
• Drugs that cause drowsiness, such as benzodiazepines, opioids, or certain antidepressants, may have enhanced sedative effects when taken with this medication.
• Alcohol consumption should be minimized as it can increase the risk of side effects like dizziness and drowsiness.
• Antihypertensive medications might be less effective when taken with pseudoephedrine due to its vasoconstrictive properties.
• Dextromethorphan can interact with certain antidepressants (e.g., SSRIs, MAOIs) and increase the risk of serotonin syndrome.
• It may also reduce the effectiveness of certain antipsychotic medications.
• Triprolidine may intensify the sedative effects of other central nervous system depressants, including antihistamines, opioids, and alcohol.

Following are the food interactions for Pseudoephedrine, dextromethorphan, Triprolidine Syrup/Suspension:

• Avoid consuming alcohol while taking this medication as it can intensify the drowsiness caused by the antihistamine (Triprolidine) and impair your ability to drive or operate machinery.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Dextromethorphan, potentially leading to increased side effects.
• Caffeine-containing products like coffee, tea, or energy drinks should be limited as Pseudoephedrine can already cause stimulation and increased heart rate, and combining it with caffeine may exacerbate these effects.
• Avoid eating or drinking large amounts of chocolate, especially dark chocolate, as it contains a compound called theobromine, which can also stimulate the heart and nervous system, potentially interacting with Pseudoephedrine.
• Dairy products like milk and cheese might slow down the absorption of certain ingredients, particularly Pseudoephedrine, although this effect is usually minimal.
• Fatty meals might also slightly delay the absorption of the medication, but this is generally not a significant concern.
• Always follow the dosage instructions provided by your healthcare provider, and ensure you inform them about any dietary habits or preferences that might impact your treatment.

Pseudoephedrine, dextromethorphan, and triprolidine syrup/suspension should be stored in a secure and controlled environment, preferably in a locked cabinet or a designated medication storage area. Keep it at room temperature, away from excessive heat, direct sunlight, and moisture. Ensure the container is tightly sealed to maintain its integrity and prevent contamination. It is crucial to dispose of any expired or unused medication properly, as flushing it down the toilet or pouring it into a drain can cause environmental harm. Contact your pharmacist or local waste management authorities for guidance on appropriate disposal methods. Always keep medications out of the sight and reach of children to prevent accidental consumption.

Following are the quick tips for Pseudoephedrine, dextromethorphan, Triprolidine Syrup/Suspension:

• Consult a doctor or pharmacist for dosage instructions specific to your age and condition.
• Administer the syrup/suspension as directed by your healthcare professional.
• Ensure you understand the prescribed dosage and duration of treatment.
• Measure the dose accurately using the provided measuring device.
• Avoid using other similar medications simultaneously without medical advice.
• Store the medication at room temperature, away from light and moisture.
• Do not share this medication with others, even if their symptoms are similar.