Actifed-P Cold (1.5/36/300mg) 400 Tablets

Pseudoephedrine and triprolidine are the active ingredients in the combination medication Pseudoephedrine, triprolidine Tablet. Pseudoephedrine primarily acts as a sympathomimetic amine, stimulating alpha-adrenergic receptors in the respiratory tract, leading to vasoconstriction and reduced congestion. This action helps to relieve nasal and sinus congestion by shrinking swollen blood vessels and allowing for improved airflow. Triprolidine, on the other hand, is an antihistamine that blocks H1-receptor sites, preventing the actions of histamine. This mechanism helps to alleviate symptoms such as sneezing, itching, and runny nose, which are often associated with allergic reactions. By combining these two mechanisms, the medication provides relief from various symptoms related to allergies and respiratory congestion.

Antihistamine-decongestant

Tablet

The following are the uses of Pseudoephedrine, triprolidine Tablet:

• Used for relieving symptoms of sinus congestion, runny nose, sneezing, and pressure or pain in the face associated with upper respiratory infections or allergies.
• Used for reducing nasal inflammation and opening blocked nasal passages, making breathing easier.
• Used for treating symptoms of the common cold, providing temporary relief from nasal congestion and runny nose.
• Used for controlling allergic reactions by blocking histamine receptors, reducing symptoms like itchy, watery eyes and sneezing.
• Used for helping patients find relief from sinus headaches and facial discomfort caused by sinus inflammation.
• Used for restoring free breathing through the nose, especially beneficial for those with nasal congestion due to allergies or colds.
• Used for managing post-nasal drip, reducing the sensation of mucus running down the back of the throat.
• Used for providing a short-term solution to upper respiratory tract discomfort, allowing patients to find temporary comfort.

In the case of an overdose of Pseudoephedrine and Triprolidine tablets, individuals may experience symptoms such as rapid heart rate, anxiety, dizziness, and severe drowsiness. It is crucial to seek medical assistance promptly if an overdose is suspected. The healthcare provider will likely recommend inducing vomiting or administering activated charcoal to prevent further absorption of the medication. Immediate medical intervention is essential to manage potential complications and ensure the patient's safety.

In the case of a missed dose of Pseudoephedrine and Triprolidine tablets, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare professional for advice on how to get back on track with your medication regimen.

To take Pseudoephedrine, triprolidine tablets, swallow the prescribed number of tablets whole with a full glass of water, following the dosage instructions provided by your healthcare professional; take the medication as directed, typically every 4 to 6 hours, but avoid taking it close to bedtime to prevent potential sleep disturbances.

Here are the conditions and situations when Pseudoephedrine, triprolidine Tablet should not be used:

• Avoid use in individuals with a known allergy or hypersensitivity to Pseudoephedrine, triprolidine, or similar decongestants and antihistamines.
• Not suitable for patients with narrow-angle glaucoma.
• Contraindicated in individuals with severe cardiovascular diseases, including uncontrolled high blood pressure, coronary artery disease, and cardiac arrhythmias.
• Should not be used in patients with severe hypertension.
• Avoid use in individuals with an overactive thyroid (hyperthyroidism).
• Not recommended for patients with severe liver or kidney disease.
• Do not use in patients with severe or uncontrolled diabetes.
• Contraindicated during pregnancy, especially in the first trimester.
• Should not be used in breastfeeding women.
• Avoid use in patients with urinary retention or an enlarged prostate.
• Not suitable for individuals with a history of seizures or convulsions.

The side effects of Pseudoephedrine, triprolidine Tablet may include:

• Drowsiness
• Dry mouth
• Nausea and vomiting
• Constipation
• Dizziness
• Nervousness or restlessness
• Increased heart rate
• Difficulty in urination

Here are the precautions and warnings for Pseudoephedrine, triprolidine Tablet:

• Not suitable for individuals with known allergies to Pseudoephedrine or triprolidine or any other decongestants or antihistamines.
• Patients with heart conditions, high blood pressure, diabetes, thyroid problems, or prostate issues should use with caution and under medical supervision.
• May cause drowsiness and impair your thinking or reactions; avoid driving or operating machinery until you know how this medication affects you.
• Avoid alcohol consumption as it can increase the side effects of this medication.
• Do not use this medication if you have taken an MAO inhibitor in the past 14 days.
• Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as this medication may pose risks to the fetus or infant.
• This medication may interact with other medicines; inform your doctor about all medications you are currently taking.
• Keep this medication out of the reach of children and pets, and store it at room temperature away from moisture and heat.

Following are the drug interactions for Pseudoephedrine, Triprolidine Tablet:

• Concomitant use with monoamine oxidase inhibitors (MAOIs), such as phenelzine or tranylcypromine, may cause severe hypertension and life-threatening interactions.
• Other sympathomimetic drugs, including decongestants or stimulants, may increase the risk of elevated blood pressure and heart rate when combined with pseudoephedrine.
• Antihypertensive medications may have reduced effectiveness when combined with pseudoephedrine, as it may increase blood pressure.
• Triprolidine, an antihistamine, may enhance the sedative effects of central nervous system depressants like alcohol, benzodiazepines, or opioids.
• The combination of triprolidine and pseudoephedrine may increase the risk of dry mouth, dizziness, or drowsiness, particularly in sensitive individuals.
• Other sedatives, including sleep aids or muscle relaxants, may have an increased sedative effect when used with triprolidine.
• Triprolidine may interact with alcohol, increasing the risk of drowsiness and impaired coordination.
• Use with other anticholinergic medications (e.g., scopolamine) may increase the risk of dry mouth, urinary retention, and constipation.

Following are the food interactions for Pseudoephedrine, triprolidine Tablet:

• Grapefruit and grapefruit juice should be avoided as they can increase the concentration of the drug in the body, leading to potential side effects.
• Alcohol consumption should be limited as it may cause increased drowsiness and dizziness, especially when combined with the sedative effects of triprolidine.
• Caffeine-rich foods and beverages like coffee, tea, and energy drinks should be consumed in moderation as they can increase blood pressure and heart rate, especially when combined with pseudoephedrine.
• High-sodium foods should be consumed sparingly as pseudoephedrine can cause water retention, and excess sodium may increase blood pressure.
• Avoid consuming large, heavy meals, especially before bedtime, as this may slow down the absorption of the medication and potentially cause discomfort.
• Keep a balanced diet and ensure adequate hydration to support overall health and well-being during the medication course.
• There are no specific food restrictions, but it is advisable to follow a healthy diet to maintain overall wellness while taking this medication.
• Always consult your healthcare provider for personalized advice regarding dietary considerations and potential interactions.

Pseudoephedrine, triprolidine tablets should be stored in a secure and dry location, preferably in a medicine cabinet, at room temperature (68°F to 77°F or 20°C to 25°C). Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to moisture or humidity. It is crucial to place the medication out of the reach of children and pets to ensure safety. Disposal of unused or expired tablets should be done responsibly; do not flush them down the toilet or discard them into the trash. Instead, utilize medicine take-back programs or consult your local pharmacist for guidance on appropriate disposal methods to minimize environmental impact and prevent misuse.

Following are the quick tips for Pseudoephedrine, Triprolidine Tablet:

• Consult a doctor or pharmacist before use, especially if you have a medical condition or are taking other medications.
• Take the tablet with a full glass of water as directed by your healthcare provider.
• Do not crush or chew the tablet; swallow it whole for optimal absorption.
• Avoid consuming alcohol or operating heavy machinery as the medication may cause drowsiness.
• If you experience dry mouth, drink plenty of fluids and consider sugar-free candies or gum.
• Store the medication at room temperature, away from light and moisture.
• Dispose of any unused or expired medication properly, do not flush down the toilet.