Adenuric (40mg) 20 Tablets

Febuxostat 40mg Tablet is a medication used primarily to manage hyperuricemia in patients with gout. It works by inhibiting the enzyme xanthine oxidase, which plays a crucial role in the production of uric acid. By blocking xanthine oxidase, Febuxostat decreases the production of uric acid, thereby lowering its levels in the blood and preventing the formation of uric acid crystals in joints and tissues. This helps in reducing the risk of gout attacks and the associated pain and inflammation.

Febuxostat 40mg

xanthine oxidase inhibitors.

Tablet

The following are the uses of Febuxostat 40mg Tablet:

• Management of hyperuricemia (high uric acid levels) in patients with gout.
• Prevention and treatment of gout attacks by lowering serum uric acid levels.
• Used in the long-term treatment of chronic gout to reduce the frequency of gout flare-ups.
• May be used in patients who cannot tolerate allopurinol, another medication used for gout management.
• Prevention of uric acid nephropathy in patients with gout or hyperuricemia, especially those undergoing chemotherapy.

Following are the doses of Febuxostat 40mg Tablet:

• The usual starting dose for adults is 40mg once daily.
• If the target serum uric acid level is not achieved after two weeks, the dose may be increased to 80mg once daily, as prescribed by the healthcare provider.
• The dose should be adjusted based on the patient's response to treatment and serum uric acid levels.
• Febuxostat should be taken orally, with or without food, at the same time each day to help remember.

In case of an overdose of Febuxostat 40mg Tablet, immediate medical attention should be sought. Overdosing on Febuxostat may lead to an increase in the risk of side effects such as liver enzyme abnormalities, skin rashes, or gastrointestinal symptoms. If you suspect an overdose, contact your healthcare provider or a poison control center immediately. Do not take additional doses to make up for the missed one, and avoid any actions without consulting a healthcare provider. Always follow the prescribed dosage and usage instructions to avoid overdose.

If you miss a dose of Febuxostat 40mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once to make up for the missed dose, as this could increase the risk of side effects. Always follow the dosing instructions provided by your healthcare provider and consult them if you're unsure about how to proceed after missing a dose.

To use Febuxostat 40mg Tablet, follow the instructions provided by your healthcare provider or as indicated on the prescription label. Typically, it should be taken once daily, with or without food. Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet. It's important to take the medication at the same time each day to help you remember and maintain consistent levels in your body.

Following are the situations when Febuxostat 40mg Tablet should not be used:

• Should not be used in individuals with a known allergy to Febuxostat or any of its components.
• Contraindicated in patients with a history of hypersensitivity reactions to xanthine oxidase inhibitors.
• Not recommended for use in patients with severe liver impairment or decompensated liver disease.
• Should be avoided in patients with a history of heart problems such as a recent myocardial infarction or unstable angina, as it may worsen cardiovascular conditions.
• Should not be used in pregnant or breastfeeding women unless prescribed by a healthcare provider, as its safety during pregnancy and lactation is not well established.

The side effects of Febuxostat 40mg Tablet may include:

• Headache
• Nausea
• Diarrhea
• Liver enzyme elevations
• Skin rash
• Gout flare-ups during the initial treatment phase
• Joint pain
• Fatigue
• Abdominal pain

Following are the precautions and warnings for Febuxostat 40mg Tablet:

• Should not be used in individuals with a known allergy to Febuxostat or any of its components.
• Caution is advised in patients with a history of liver disease, as the medication can elevate liver enzymes and may cause liver damage.
• Not recommended for patients with severe renal impairment, as it may worsen kidney function.
• Use with caution in patients with a history of cardiovascular disease, as Febuxostat may increase the risk of heart-related issues, particularly in those with pre-existing conditions.
• Regular monitoring of liver function and uric acid levels is recommended during treatment.
• Avoid abrupt discontinuation of the medication without consulting a healthcare provider, as this may lead to a gout flare.

Following are the drug interactions for Febuxostat 40mg Tablet:

• Concomitant use with certain purine analogs (e.g., azathioprine, mercaptopurine) should be avoided, as Febuxostat can increase their levels and lead to toxicity.
• Caution is advised when using Febuxostat with medications that affect liver enzymes, such as theophylline, as they may increase the risk of liver enzyme abnormalities.
• Use with warfarin or other anticoagulants may require careful monitoring of blood clotting parameters, as Febuxostat could enhance the anticoagulant effect.
• Febuxostat may interact with diuretics, particularly thiazide diuretics, which can increase uric acid levels and potentially reduce the effectiveness of Febuxostat.
• Inform your healthcare provider about all other medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.

Following are the food interactions for Febuxostat 40mg Tablet:

• There are no significant food interactions with Febuxostat; however, it is recommended to take the medication consistently with or without food to maintain a routine.
• It is important to stay hydrated and drink plenty of fluids, as dehydration can lead to elevated uric acid levels.
• While specific foods do not directly interact with Febuxostat, a healthy diet low in purines, found in red meats, organ meats, and certain seafood, is encouraged to help manage gout.
• Alcohol consumption should be limited, as it can increase uric acid levels and may reduce the effectiveness of the medication. Always consult your healthcare provider about any dietary changes.

Febuxostat 40mg Tablet should be stored at room temperature, away from moisture and heat. It is recommended to keep the medication in its original container, tightly closed, and out of reach of children. Do not store the medication in the bathroom or near a sink, as excess moisture can affect the integrity of the tablets. If the medication is expired or no longer needed, do not flush it down the toilet or pour it into a drain. Properly dispose of unused or expired medication by taking it to a drug take-back program or by following the disposal instructions provided by your healthcare provider or local pharmacy. Always ensure that any medication is disposed of safely to avoid accidental ingestion or misuse.

Following are the quick tips for Febuxostat 40mg Tablet:

• Take Febuxostat as prescribed by your healthcare provider, usually once daily, with or without food.
• Do not skip doses or stop taking the medication without consulting your healthcare provider, even if you feel better.
• Drink plenty of water to stay hydrated, as dehydration can increase uric acid levels.
• Limit alcohol consumption, as it may interfere with the effectiveness of the medication.
• Follow a low-purine diet to help reduce uric acid levels and prevent gout attacks.
• Regularly monitor your uric acid levels and liver function as advised by your healthcare provider.
• If you experience any unusual symptoms such as skin rash or stomach discomfort, contact your healthcare provider promptly.