Admore (100000 IU) 2 Tablets

Cholecalciferol, also known as vitamin D3, has a primary mechanism of action centered on its role in calcium and phosphate metabolism. When administered, cholecalciferol is converted in the liver to 25-hydroxycholecalciferol (calcidiol) and then in the kidneys to its active form, 1,25-dihydroxycholecalciferol (calcitriol). Calcitriol acts as a hormone, binding to vitamin D receptors (VDRs) in various target tissues. This binding activates specific genes, leading to increased intestinal absorption of calcium and phosphate. In the kidneys, calcitriol promotes calcium reabsorption, reducing urinary calcium excretion. This overall increase in calcium and phosphate levels contributes to the mineralization and maintenance of bone health. Additionally, cholecalciferol's mechanism involves regulating parathyroid hormone (PTH) secretion, which further influences calcium homeostasis and bone remodeling.

Cholecalciferol 100,000iu

Vitamin D analog

Tablet

The following are the uses of Cholecalciferol 100,000iu Tablet:

• Used for treating Vitamin D deficiency and related bone disorders.
• Used to prevent and treat rickets in children.
• Used to support calcium absorption for stronger bones.
• Used in the management of hypocalcemia (low calcium levels).
• Used to promote bone health in individuals with limited sun exposure.
• Used for maintaining bone density and reducing fracture risk.
• Used to regulate the immune system and support overall health.
• Used as a supplement for individuals with malabsorption issues.

In the case of an overdose of Cholecalciferol 100,000 IU tablets, individuals may experience a range of symptoms. These can include nausea, vomiting, weakness, and frequent urination. Overdose can lead to a significant increase in calcium levels in the body, potentially causing kidney damage and other serious health issues. It is important to seek medical advice promptly if an overdose is suspected, as treatment may involve managing symptoms and preventing further complications.

In the case of a missed dose of Cholecalciferol 100,000 IU Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is important to maintain a consistent dosing regimen, but if you frequently miss doses, consult your healthcare provider for advice on how to manage your medication effectively.

To take Cholecalciferol 100,000 IU Tablet, place the tablet on your tongue and allow it to dissolve completely, preferably at the same time each day, or as directed by your healthcare professional.

Following are the conditions or situations when Cholecalciferol 100,000iu Tablet should not be used:

• Avoid if you have a known allergy or hypersensitivity to vitamin D, fish, or any of the excipients in the tablet.
• Do not take if you have high calcium levels in your blood (hypercalcemia) or urine (hypercalciuria).
• Contraindicated in individuals with evidence of vitamin D toxicity.
• Should not be used in patients with kidney stones or a history of kidney disease.
• Avoid if you have a condition called hyperparathyroidism, where the parathyroid gland is overactive.
• Not recommended for individuals with cardiovascular disease or a history of heart attacks.
• Do not use if you have a condition called sarcoidosis, where vitamin D metabolism is altered.

The side effects of Cholecalciferol 100,000 IU Tablet may include:

• Nausea and vomiting
• Diarrhea
• Constipation
• Dry mouth
• Metallic taste
• Fatigue and weakness
• Muscle or bone pain
• Increased calcium levels in the blood (hypercalcemia)

Following are the precautions and warnings for Cholecalciferol 100,000iu Tablet:

• Do not exceed the recommended dosage, as excessive vitamin D intake can lead to hypervitaminosis D, causing serious side effects.
• Patients with a history of kidney stones or kidney disease should use this medication with caution and under medical supervision.
• Individuals with hypercalcemia (high calcium levels in the blood) should not take this medication as it can worsen the condition.
• Regular monitoring of calcium and phosphate levels is necessary during long-term treatment.
• This medication may cause an increase in blood calcium levels, leading to potential heart rhythm issues; monitor closely if you have a history of heart problems.
• Cholecalciferol tablets may interact with certain medications, including antacids, cholesterol-lowering drugs, and steroids; consult your doctor if you are on any medication.
• If you have a history of gastrointestinal disorders, absorption of this medication may be affected, requiring medical advice.
• Keep out of reach of children; accidental overdose can have severe consequences.

Following are the drug interactions for Cholecalciferol 100,000 IU Tablet:

• Anticonvulsants like phenobarbital, phenytoin, and carbamazepine can reduce vitamin D levels and may decrease the effectiveness of Cholecalciferol.
• Cholestyramine and colestipol can decrease the absorption of vitamin D by binding to it in the intestine, thus reducing its effectiveness.
• Orlistat and olestra can reduce the absorption of fat-soluble vitamins, including vitamin D, leading to potential deficiencies.
• Aluminum-containing antacids can decrease the absorption of vitamin D, potentially reducing its efficacy.
• Thiazide diuretics can increase calcium levels, and when combined with Cholecalciferol, may lead to hypercalcemia.
• Corticosteroids may decrease calcium absorption, and concurrent use with Cholecalciferol may require higher vitamin D doses.
• Calcium supplements, when taken with Cholecalciferol, may require monitoring for potential hypercalcemia, especially in patients with hyperparathyroidism.

Following are the food interactions for Cholecalciferol 100,000 IU Tablet:

• Consuming excessive amounts of vitamin D-rich foods like fatty fish (salmon, mackerel), egg yolks, and fortified dairy products alongside the tablet may lead to vitamin D toxicity.
• Vitamin D absorption can be enhanced by including healthy fats in your diet, such as avocados, nuts, and olive oil, as it is a fat-soluble vitamin.
• Avoid excessive alcohol consumption as it can interfere with vitamin D metabolism and reduce its effectiveness.
• Certain medications, such as corticosteroids and anti-seizure drugs, can impact vitamin D levels, so discuss any ongoing medications with your healthcare provider.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect vitamin D metabolism, potentially leading to imbalances.
• Calcium-rich foods like dairy, leafy greens, and fortified alternatives can support vitamin D's role in bone health, aiding absorption.
• Maintain a balanced diet to ensure you're not exceeding the recommended vitamin D intake, as high doses can be harmful.
• Always consult a healthcare professional for personalized advice, especially if you have specific dietary restrictions or medical conditions.

Cholecalciferol 100,000iu Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area. Keep the tablets in their original packaging, ensuring the container is tightly sealed to maintain their integrity and prevent exposure to moisture. It is crucial to protect the medication from direct sunlight, as it can degrade the active ingredients. Avoid storing in bathrooms or kitchens due to temperature fluctuations and humidity. Always check the expiration date, and never use the medication beyond its expiry. For disposal, do not flush or pour the tablets down the drain; instead, consult a pharmacist or healthcare professional for guidance on proper disposal methods to ensure environmental safety. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Cholecalciferol 100,000iu Tablet:

• Consult a doctor before use, especially if you have a medical condition or are taking other medications.
• Take the tablet as directed by your healthcare provider; do not exceed the prescribed dosage.
• Swallow the tablet whole with a glass of water; do not crush or chew.
• Take the tablet with a meal to enhance absorption.
• Maintain a consistent dosing schedule for best results.
• Store the medication in a cool, dry place, away from direct sunlight and moisture.
• Do not share your medication with others, even if they have similar symptoms.
• Regularly monitor your vitamin D levels as advised by your doctor.