Albact (200mg) 10 Tablets

Norfloxacin 200mg Tablet, a synthetic chemotherapeutic agent, exerts its antibacterial effect by inhibiting DNA gyrase, a type II topoisomerase enzyme essential for bacterial DNA replication, transcription, and repair. Specifically, norfloxacin binds to the A subunit of DNA gyrase, blocking its ability to introduce negative supercoils into DNA, which is necessary for DNA unwinding and subsequent DNA synthesis. This interference leads to the disruption of DNA replication and transcription, ultimately resulting in bacterial cell death. Norfloxacin is particularly effective against bacteria because it targets an enzyme that is unique to prokaryotic cells, making it selectively toxic to bacterial cells while minimizing harm to human cells.

Fluoroquinolone antibiotic

Tablet

The following are the uses of Norfloxacin 200mg Tablet:

• Used for treating bacterial infections, especially those affecting the urinary tract.
• Used for conditions like gonorrhea, a sexually transmitted infection.
• Used for respiratory tract infections such as pneumonia.
• Used for gastrointestinal infections, including bacterial diarrhea.
• Used for preventing and treating infections in individuals with a weakened immune system.
• Used for skin and soft tissue infections caused by susceptible bacteria.
• Used for certain types of prostate infections.
• Used for post-surgery infection prevention, especially in high-risk procedures.

In the case of an overdose of Norfloxacin 200mg Tablets, individuals may experience severe adverse effects. These can include gastrointestinal disturbances, central nervous system reactions, and cardiovascular issues. Prompt medical intervention is necessary, as symptoms may range from nausea and vomiting to seizures, dizziness, and potentially life-threatening arrhythmias. Quick action can help mitigate these risks and ensure the well-being of the affected individual.

In the case of a missed dose of Norfloxacin 200mg Tablet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for advice on how to safely adjust your medication regimen. Do not stop taking the medication without consulting your doctor, as this may affect the effectiveness of the treatment.

To take Norfloxacin 200mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, either with or without food, as directed by your healthcare professional.

Following are the conditions/situations when Norfloxacin 200mg Tablet should not be used:

• Should not be used in individuals with a known allergy to Norfloxacin or other quinolone antibiotics.
• Contraindicated in patients with a history of seizures or epilepsy, as it may lower the seizure threshold.
• Not recommended for individuals with myasthenia gravis, as it may worsen muscle weakness.
• Should be avoided in patients with a history of tendon disorders or tendon rupture, especially those related to previous quinolone use.
• Contraindicated in patients with severe kidney disease or those on dialysis, as dosage adjustments are necessary.
• Not suitable for children and adolescents under 18 years of age, as safety and efficacy have not been established.
• Should be used with caution and avoided if possible in elderly patients, especially those at risk of joint and tendon disorders.
• Avoid exposure to sunlight or UV rays, as Norfloxacin may increase sensitivity to light and cause severe sunburn.

The side effects of Norfloxacin 200mg Tablet may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain or discomfort
• Headache
• Dizziness
• Skin rash or itching
• Sensitivity to sunlight (photosensitivity)
• Sleep disturbances

Following are the precautions and warnings for Norfloxacin 200mg Tablet:

• Not recommended for individuals with a known hypersensitivity or allergy to Norfloxacin or other quinolone antibiotics.
• Patients with a history of epilepsy or other seizure disorders should exercise caution, as Norfloxacin may lower the seizure threshold.
• Should be used with caution in patients with kidney or liver disease, as dosage adjustments might be necessary.
• Avoid excessive exposure to sunlight or UV rays while taking Norfloxacin, as it may increase sensitivity to sunlight.
• Not recommended for children, adolescents, pregnant women, and breastfeeding mothers due to potential risks associated with the use of fluoroquinolones.
• Elderly patients may be more susceptible to joint and tendon problems, so they should be closely monitored during treatment.
• Discontinue the medication and seek medical attention if any severe side effects occur, such as tendon pain, central nervous system effects, or severe allergic reactions.
• Norfloxacin may cause dizziness or lightheadedness; patients should avoid driving or operating heavy machinery until they know how the medication affects them.

Following are the drug interactions for Norfloxacin 200mg Tablet:

• Concomitant use with antacids containing aluminum, magnesium, or calcium can reduce the absorption of norfloxacin, leading to decreased effectiveness.
• Iron, zinc, and sucralfate may also interfere with the absorption of norfloxacin, reducing its therapeutic effect.
• Theophylline levels may increase when used with norfloxacin, leading to a higher risk of toxicity, including nausea, seizures, or cardiac arrhythmias.
• Warfarin and other anticoagulants may have an increased anticoagulant effect when combined with norfloxacin, requiring close monitoring of INR levels.
• Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, may increase the risk of central nervous system stimulation and seizures when used with norfloxacin.
• Corticosteroids may increase the risk of tendon rupture when taken with norfloxacin, especially in elderly patients.
• Drugs that prolong the QT interval, such as amiodarone or erythromycin, may further increase the risk of QT prolongation and cardiac arrhythmias when combined with norfloxacin.

Following are the food interactions for Norfloxacin 200mg Tablet:

• Avoid caffeine-containing products like coffee, tea, energy drinks, and certain soft drinks. Caffeine can increase the side effects of Norfloxacin, leading to increased nervousness, anxiety, and insomnia.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Norfloxacin, potentially increasing its levels in the body and the risk of side effects.
• Avoid excessive alcohol consumption. Alcohol can increase the risk of central nervous system side effects such as dizziness, confusion, and drowsiness.
• Dairy products like milk, yogurt, and cheese may decrease the absorption of Norfloxacin. Consider separating these by several hours to ensure optimal absorption.
• Iron-rich foods like red meat, spinach, and iron supplements can reduce the absorption of Norfloxacin. Take Norfloxacin 2 hours before or 2 hours after these products.
• Avoid high-fat meals as they may decrease the absorption of Norfloxacin, reducing its effectiveness.
• Ensure adequate hydration by drinking plenty of water to reduce the risk of side effects related to the kidneys.
• Vitamin-rich foods or supplements, especially those containing Vitamin A, C, and E, may interact with Norfloxacin. Consult your healthcare provider for specific guidance on vitamin intake.

Norfloxacin 200mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. It is crucial not to store them in the bathroom or near heat-emitting appliances, as temperature fluctuations can impact their effectiveness. Always check the expiration date, and for proper disposal, consult a pharmacist or healthcare professional to ensure responsible environmental practices. Keep the medication away from children to prevent accidental consumption.

Following are the quick tips for Norfloxacin 200mg Tablet:

• Take the tablet as directed by your doctor, usually twice a day.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Avoid taking it with dairy products, iron, or antacids; take it 2 hours before or after these products.
• Maintain a good fluid intake while on this medication.
• Complete the full course as prescribed, even if you feel better earlier.
• Inform your doctor if you have any allergies or medical conditions before taking this medicine.
• Store the tablets at room temperature, away from moisture and heat.