Alka-Seltzer 36 Tablets

The Citric acid/Aspirin/sodium bicarbonate combination tablet has a synergistic mechanism of action for its constituents. Aspirin (acetylsalicylic acid) is a well-known non-steroidal anti-inflammatory drug (NSAID) that inhibits the enzyme cyclooxygenase (COX), leading to a reduction in prostaglandin synthesis, which in turn provides analgesic, antipyretic, and anti-inflammatory effects. Citric acid, being a weak organic acid, contributes to the effervescent property of the tablet when combined with sodium bicarbonate, a basic compound. This reaction releases carbon dioxide gas, which can aid in the rapid disintegration and dissolution of the tablet, potentially enhancing the absorption of aspirin. Sodium bicarbonate also helps neutralize stomach acid, which can protect the aspirin from degradation in the acidic environment of the stomach and facilitate its absorption in the small intestine.

Citric acid/Aspirin/sodium bicarbonate

Antacid/Analgesic/Antiplatelet

Tablet

The following are the uses of Citric acid/Aspirin/sodium bicarbonate Tablet:

• Used for relieving heartburn, acid indigestion, and upset stomach.
• Used as an antacid to neutralize excess stomach acid.
• Used for temporary relief of acid-related symptoms like sour stomach and acid reflux.
• Used to reduce pain and inflammation, such as headaches, toothaches, and muscle aches.
• Used as an antipyretic to reduce fever.
• Used for promoting quick relief from symptoms of heartburn, acid indigestion, sour stomach, and gas pain.
• Used to create a fizzing reaction when combined with water, which can be utilized for cleaning or science experiments.
• Used for gentle exfoliation and brightening the skin when included in skincare routines.

In the case of an overdose of Citric acid/Aspirin/sodium bicarbonate tablets, individuals may experience symptoms such as nausea, vomiting, abdominal pain, and in severe cases, gastrointestinal bleeding. It is important to seek medical advice promptly if an overdose is suspected. Treatment for overdose involves managing the symptoms and providing supportive care. This may include gastric lavage, activated charcoal administration, and close monitoring of vital signs and laboratory parameters.

In the case of a missed dose of Citric acid/Aspirin/sodium bicarbonate Tablet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one, as this may increase the risk of side effects. It is essential to maintain a consistent dosing schedule, but if you miss a dose, consult your healthcare provider for further guidance if needed.

To take the Citric acid/Aspirin/sodium bicarbonate tablet, simply place the tablet on your tongue and allow it to dissolve, or dissolve it in a glass of water and drink the mixture. Take the tablet as directed by your healthcare provider, typically with a full glass of water, and follow the recommended dosage instructions provided on the product packaging.

Here are the situations when Citric acid/Aspirin/sodium bicarbonate Tablet should not be used:

• Do not take if you have a known allergy to any of the ingredients, including citric acid, aspirin (acetylsalicylic acid), or sodium bicarbonate.
• Avoid if you have a bleeding disorder or are taking blood-thinning medications, as aspirin can increase the risk of bleeding.
• Not suitable for individuals with a history of stomach ulcers or gastrointestinal bleeding.
• Contraindicated in patients with severe kidney disease or those with a high risk of developing kidney problems.
• Should not be used in children and adolescents under 16 years of age with a fever, or as directed by a doctor.
• Avoid using this medication if you have a history of asthma attacks triggered by aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs).
• Do not take this medication if you have had recent heart surgery or a history of bleeding in the brain (intracranial hemorrhage).
• Not recommended for individuals with severe dehydration or those with low sodium levels in the blood (hyponatremia).
• Avoid using this medication if you are about to undergo dental surgery or any other procedure that may cause bleeding.
• Should not be used during the last three months of pregnancy unless directed by a healthcare professional.

The side effects of Citric acid/Aspirin/sodium bicarbonate Tablet may include:

• Stomach pain or discomfort
• Nausea and vomiting
• Heartburn or indigestion
• Increased urination
• Headache
• Dizziness
• Ringing in the ears (tinnitus)
• Allergic reactions (such as rash, itching, or difficulty breathing)

Here are the precautions and warnings for Citric acid/Aspirin/sodium bicarbonate Tablet:

• This medication should be avoided by individuals with a known allergy to aspirin, citric acid, or sodium bicarbonate.
• Patients with a history of gastrointestinal bleeding, peptic ulcers, or asthma should use with caution, as aspirin can aggravate these conditions.
• Not recommended for children and teenagers recovering from viral infections due to the risk of Reye's syndrome.
• May cause temporary tooth sensitivity, so it is advisable to avoid prolonged contact with teeth.
• Patients with kidney or liver disease should consult a doctor before use, as dosage adjustments may be necessary.
• Do not exceed the recommended dosage, as it may lead to serious side effects.
• Discontinue use and seek medical attention if you experience severe stomach pain, persistent nausea, or signs of bleeding.
• Keep out of reach of children, as accidental ingestion may be harmful.

Following are the drug interactions for Citric acid/Aspirin/sodium bicarbonate Tablet:

• Aspirin may interact with anticoagulants/antiplatelet drugs, increasing the risk of bleeding.
• Can decrease uric acid levels, affecting the action of uricosurics like probenecid.
• May reduce the absorption of certain medications, such as tetracyclines, iron supplements, and ACE inhibitors.
• Antacids containing sodium bicarbonate can reduce the absorption of medications like ketoconazole and amphetamines.
• Concurrent use with carbonic anhydrase inhibitors (e.g., acetazolamide) may increase the risk of metabolic alkalosis.
• Aspirin may interact with corticosteroids, increasing the risk of gastrointestinal bleeding.
• Citric acid may enhance the absorption of aluminum-containing antacids, leading to increased aluminum levels.

Following are the food interactions for Citric acid/Aspirin/sodium bicarbonate Tablet:

• Alcohol intake should be avoided as it can increase the risk of stomach bleeding and irritate the stomach lining, especially when combined with aspirin.
• Citrus fruits and juices, like oranges and lemons, can potentially increase the absorption of aspirin, which may enhance its effects and increase the risk of side effects.
• Foods high in vitamin C, such as broccoli, bell peppers, and strawberries, can also impact aspirin absorption, similar to citrus fruits.
• Salty foods and sodium-rich diets should be consumed in moderation as sodium bicarbonate is a source of sodium, and excessive intake can lead to sodium retention and increased blood pressure.
• Avoid high-fat meals as they may delay the absorption of aspirin, potentially reducing its effectiveness.
• Dairy products, especially milk, might interfere with the absorption of aspirin, so it's best to separate them by a few hours.
• Avoid spicy foods as they can irritate the stomach, and when combined with aspirin, may increase the risk of gastrointestinal issues.
• There is no significant interaction with caffeine, but excessive caffeine intake might cause jitters or insomnia, especially with the stimulating effects of citric acid.

Citric acid, aspirin, and sodium bicarbonate tablets should be stored in a cool, dry place, preferably at room temperature, ensuring protection from light and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. Avoid exposing them to heat or humidity, as it can degrade the medication. Dispose of any unused or expired tablets responsibly; do not flush them or pour them down the drain. Consult your pharmacist for guidance on safe disposal practices. Keep all medications out of children's reach to prevent accidental consumption, ensuring their safety. Proper storage and disposal are essential to maintain the effectiveness of these tablets and prevent any potential harm.

Following are the quick tips for Citric acid/Aspirin/sodium bicarbonate Tablet:

• Consult your healthcare provider before taking these tablets, especially if you have any medical conditions or allergies.
• Follow the dosage instructions provided by your doctor or pharmacist.
• Dissolve the tablet completely in a glass of water before drinking.
• Do not chew or crush the tablets, swallow them whole.
• Avoid taking this medication on an overly full or empty stomach.
• If you experience stomach discomfort, take it with food or after meals.
• Store the tablets in a cool, dry place, away from direct sunlight.