ALKIN 120ML SYP

Disodium Hydrogen Citrate Syrup/Suspension acts primarily by providing a source of citrate ions, which are responsible for its therapeutic effects. Citrate ions work by binding to calcium ions in the urine, forming a soluble complex called calcium citrate. This mechanism helps prevent the formation of calcium oxalate and calcium phosphate crystals, which are the main components of kidney stones. By chelating calcium, disodium hydrogen citrate increases the solubility of these minerals, inhibiting their aggregation and promoting their elimination through urination. This process helps to dissolve existing stones and prevents the formation of new ones by maintaining a urine environment that discourages crystal growth.

Antacid/Expectorant

Suspension

The following are the uses of Disodium Hydrogen Citrate Syrup/Suspension:

• Used as an alkalizing agent to reduce acidity in the urine, helping manage urinary tract infections.
• Helps relieve symptoms of burning sensation during urination by neutralizing excess acid in the urine.
• Commonly used to prevent and manage conditions like kidney stones by reducing uric acid levels.
• Provides symptomatic relief in conditions involving acidic urine or metabolic acidosis.

In the case of an overdose of Disodium Hydrogen Citrate Syrup/Suspension, individuals may experience symptoms such as severe gastrointestinal distress, including nausea, vomiting, and diarrhea. These symptoms can lead to dehydration and electrolyte imbalances. It is important to seek medical advice promptly, as treatment may involve managing these symptoms and rehydration. Quick action can help prevent potential complications and ensure the individual's well-being.

In the case of a missed dose of Disodium Hydrogen Citrate Syrup/Suspension, it is important to administer the medication as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume the medication. It is crucial to maintain a consistent dosing routine for the best therapeutic effect.

To take Disodium Hydrogen Citrate Syrup/Suspension, shake the bottle well, then measure the prescribed dose with a measuring cup or oral syringe, and administer it orally once or twice a day as directed by your healthcare professional, ensuring accurate dosage for optimal effectiveness.

Following are the conditions/situations when Disodium Hydrogen Citrate Syrup/Suspension should not be used:

• Not recommended for individuals with a known allergy to citrates or any of the excipients in the formulation.
• Contraindicated in patients with severe renal impairment or end-stage kidney disease.
• Should be avoided in individuals with uncontrolled metabolic acidosis.
• Not suitable for patients with severe dehydration or electrolyte imbalances.
• Should not be used to treat gastrointestinal ulcers or bleeding without proper medical supervision.
• Discontinue use if it causes severe diarrhea or abdominal pain.
• Not recommended for patients with a history of gastrointestinal obstructions or severe gastrointestinal motility disorders.

The side effects of Disodium Hydrogen Citrate Syrup/Suspension may include:

• Nausea and vomiting
• Stomach pain or cramps
• Diarrhea
• Constipation
• Excessive sweating
• Increased thirst
• Electrolyte imbalance (low levels of potassium, calcium, or other minerals)
• Allergic reactions (skin rash, itching, swelling)

Following are the precautions and warnings for Disodium Hydrogen Citrate Syrup/Suspension:

• Discontinue use and consult a doctor if symptoms persist or worsen after 7 days of treatment.
• Not recommended for individuals with known allergies to citric acid or its derivatives.
• Patients with a history of kidney stones should use with caution and under medical supervision.
• May interact with certain medications; inform your doctor about all the medicines you are taking.
• Always shake the bottle well before use to ensure a uniform suspension.
• Store in a cool, dry place, away from direct sunlight, and keep out of reach of children.
• Do not exceed the recommended dosage; overdose may lead to serious side effects.

Following are the drug interactions for Disodium Hydrogen Citrate Syrup/Suspension:

• It can interact with antacids containing aluminum, reducing the effectiveness of both medications.
• The absorption of tetracycline antibiotics may be impaired when taken with Disodium Hydrogen Citrate, leading to reduced antibiotic efficacy.
• Potentially increases the risk of bleeding when used with anticoagulants like warfarin, requiring close monitoring.
• May decrease the absorption of certain medications like iron supplements, reducing their effectiveness.
• It can enhance the absorption of certain medications, such as calcium-containing drugs, potentially leading to increased side effects.
• When combined with medications that raise urinary pH, it may alter the elimination of some drugs, affecting their effectiveness.
• Interactions with other medications that affect kidney function may require dosage adjustments.

Following are the food interactions for Disodium Hydrogen Citrate Syrup/Suspension:

• Disodium Hydrogen Citrate may interact with acidic foods and beverages like citrus fruits, tomatoes, and vinegar-based dressings, as it can neutralize stomach acid and potentially reduce the absorption of certain nutrients.
• Avoid consuming excessive amounts of dairy products like milk, cheese, and yogurt, as the high calcium content can interact with Disodium Hydrogen Citrate and form insoluble calcium citrate, affecting its effectiveness.
• Limit the intake of high-sodium foods such as processed meats, canned soups, and salty snacks, as Disodium Hydrogen Citrate is a sodium-containing compound, and excessive sodium intake can lead to health issues.
• Alcohol should be consumed in moderation as it can irritate the stomach lining and potentially exacerbate gastrointestinal symptoms, especially if you have a sensitive stomach.
• Caffeinated beverages like coffee and tea should be consumed in moderation, as they can stimulate stomach acid production, which may counteract the effects of Disodium Hydrogen Citrate.
• Spicy foods and hot peppers may irritate the gastrointestinal tract and potentially worsen symptoms, especially if you have a sensitive digestive system.
• It is advisable to maintain a balanced diet and ensure adequate hydration to support the effectiveness of Disodium Hydrogen Citrate in managing your condition.

Disodium Hydrogen Citrate Syrup/Suspension should be stored in a cool and dry environment, preferably at room temperature, ensuring it is shielded from direct sunlight and moisture. Keep the medication securely sealed within its original packaging to maintain its integrity and prevent contamination. Avoid placing it in areas like the bathroom or near heat-emitting appliances, as temperature fluctuations can impact its effectiveness. When disposing of unused or expired syrup, refrain from flushing it down the toilet or pouring it into drains. Instead, consult a pharmacist or healthcare professional for guidance on safe disposal practices. Additionally, ensure the medication is stored out of children's reach to prevent accidental consumption.

Following are the quick tips for Disodium Hydrogen Citrate Syrup/Suspension:

• Consult a doctor for the correct dosage and usage based on your medical condition.
• Ensure you understand the prescribed dosage and duration of treatment.
• Shake the bottle well before each use to ensure the medication is properly mixed.
• Measure the syrup accurately using the provided measuring cup or a calibrated spoon.
• Administer the medication as directed, usually before meals for optimal effectiveness.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Regularly monitor your health and inform your doctor of any persistent or severe side effects.