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Product Information
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Description
Amlodipine: Antianginal Agent; Antihypertensive; Calcium Channel Blocker, Dihydropyridine. Amlodipine is a dihydropyridine calcium antagonist it acts by inhibiting the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscles this mechanism leads to a reduction in peripheral vascular resistance, resulting in a decrease in blood pressure.
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Ingredients
Amlodipine -
Dosage Form
Tablet -
Uses
Angina: Treatment of symptomatic chronic stable angina; treatment of confirmed or suspected vasospastic angina. May be used alone or in combination with other antianginal agents. Hypertension, chronic: Management of hypertension in adults and children ≥6 years of age.
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Dosage
Dose must be taken according to doctor’s advice only; doses given below are suggested as supportive literature for better understanding in some areas of requirements. Children dose; <6 years: Oral initial dose is; 0.1 mg/kg/dose once daily; maximum daily dose is 0.6 mg/kg/day or 5 mg/day. Children ≥6 years and Adolescents: Oral initial dose is; 2.5 mg once daily; maximum daily dose is 10 mg/day. Adult dose: Initial starting dose is 2.5mg once daily, then 5-10mg once daily, maximum daily dose is 10mg once daily.
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In case of Overdose
Consult your doctor in case of overdose, as it may cause hypotension.
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Missed Dose
In case you missed any dose, take the next dose as soon as you remember, but don't double your next dose to compensate for the missed one.
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How To Use
Take it orally with your doctor’s instructions.
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When Not to Use
Hypersensitivity to amlodipine or any component of the formulation occurs, then do not use. Do not use amlodipine during breastfeeding.
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Side Effects
acute hypotension upon initiation is unlikely due to the gradual onset of action. Blood pressure must be lowered at a rate appropriate for the patient's clinical condition. Use with caution in patients with hepatic impairment.
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Precautions & Warnings
Symptomatic hypotension can occur
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Food Interaction
Alpha1-Blockers may enhance the hypotensive effect of calcium channel blockers like
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Storage/Disposal
Amlodipine may enhance the hypotensive effect of Antipsychotic Agents.
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