Amgydex (0.3/0.1%) 5ml Eye Drops

Amgydex (0.3/0.1%) 5ml Eye Drops

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  • Manufacturer KOBEC Health Sciences
  • Generic Name

    Dexamethasone, Tobramycin

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Storage/Disposal
  • Description

    Tobramycin 0.3% is a powerful antibiotic that, when combined with dexamethasone 0.1%, a steroid with potent anti-inflammatory properties, creates a dynamic duo indicated for the treatment of ocular infections caused by several common bacteria. Tobramycin works by binding to the ribosomal subunit of susceptible bacteria, disrupting the translocation of the peptidyl-tRNA channel, and ultimately inhibiting protein synthesis. Dexamethasone acts by inhibiting the transcription of inflammatory cytokines, thereby mitigating the inflammatory response. The sophisticated mechanism of action for these medications works effectively to treat ocular infections and any corresponding inflammatory conditions.

  • Ingredients

    Dexamethasone, Tobramycin

  • Drug Class

    Tobramycin:

  • Dosage Form

    Drop

  • Uses

    Dexamethasone, Tobramycin combination is utilized for the following therapeutic indications:

    • Treatment of bacterial infections
    • Management of inflammation associated with eye conditions
    • Effective in treating bacterial conjunctivitis and keratitis
    • Provides a strong anti-inflammatory effect alongside potent antibacterial activity
    • Used for post-operative care to minimize inflammation and infection risk
    • Suitable for treating resistant infections in the ocular region.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • For Tobramycin 0.3%- For adults, the recommended dose is 1-2 drops in the affected eye every 6 hours in a 12-hour interval. For children 1 year or older, the recommended dose is 1-2 drops in the affected eye every 6 hours in a 12-hour interval.
    • For Dexamethasone 0.1%- For adults, the recommended dose is 1-2 drops in the affected eye every 6 hours in a 12-hour interval. For children 2 years or older, the recommended dose is 1-2 drops in the affected eye every 6 hours in a 12-hour interval.
  • In case of Overdose

    An overdose of Tobramycin 0.3% and Dexamethasone 0.1% can be treated with supportive care. The first step is monitoring the patient's vital signs and clinical symptoms to determine the severity of the overdose and to look for any symptoms that may have developed as a result. Fluid therapy may be used to prevent dehydration if polydipsia or diarrhea are present. Correction of electrolyte imbalances is also important to prevent further health effects from diarrhea, vomiting, or use of diuretic drugs. Management of cardiopulmonary complications is essential to treat any life-threatening conditions that may have occurred as a result of the overdose, and may include the use of respiratory support or cardiac pacing. Management of drug interactions is aimed at minimizing any further interactions with other drugs taken as part of the overdose. Emotional support is provided to the patient to help relieve stress and fear, if symptoms of anxiety or restlessness occur. Finally, the patient must be monitored for a significant amount of time, despite improved symptoms, to ensure that no long-term effects result from the overdose.

  • Missed Dose

    If you happen to miss a dose of your Tobramycin 0.3% and Dexamethasone 0.1% mixture, there is no need to double up on your next dose to make up for it. It is essential to follow the recommended dosage schedule and administer the missed dose as soon as you can. If you are confused about any aspect of this medication, contact your medical provider or anti-infective pharmacist for guidance specific to your situation. They will be able to ensure that you use this medication in the safest way possible.

  • How To Use

    Before applying Tobramycin and Dexamethasone Eye Ointment, you must read and follow the instructions provided by your doctor. Consistent and regular application of this medication, usually twice daily, is vital to gain the most advantage from it. Here is a step-by-step guide to help you use this medication:

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • If you are allergic to any of the ingredients in this medicine.
    • If you have glaucoma or cataracts.
    • If you have a viral, fungal, or bacterial infection of the nose.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Ear discomfort
    • Hearing disturbances
    • Headache
    • Dizziness
    • Nausea
    • Diarrhea
    • Skin irritation
    • Thrush (fungal infection)
    • Fluid retention
    • High blood sugar
  • Storage/Disposal

    Tobramycin and dexamethasone are two medications that require proper storage to preserve their effectiveness and safety. Tobramycin is a topical antibiotic eye drop that should be stored in a cool, dry place, such as a medicine cabinet or drawer. It should be kept away from direct heat or light and maintained at a temperature below 25°C/77°F and ideally at 5-8°C. While freezing may damage the medication, ensuring that the lid is tightly closed after each use is vital in preventing the medication from evaporating or becoming contaminated. Dexamethasone is a steroidal anti-inflammatory eye drop that also needs a cool and dry storage place. Just like Tobramycin, dexamethasone should be kept away from direct heat or light and should be stored at a temperature ranging from 15-30°C (59-86°F). Freezing this medication is not advised as well. It is important to always tightly close the lid to prevent contamination and preserve the medication. Following these storage guidelines is crucial in ensuring that these medications remain safe and effective for use. If you notice that the medications have been exposed to improper storage conditions or have exceeded the expiration date, it is essential to immediately consult a healthcare professional for guidance on how to proceed safely.

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