Amvax B (20mcg/ml) 1 Vial Injection

The mechanism of action of the Recombinant Hepatitis B Vaccine is centered on stimulating the body's immune system to produce a protective response against the Hepatitis B virus. This vaccine is engineered using recombinant DNA technology, where the hepatitis B surface antigen (HBsAg) is produced in yeast cells. When the vaccine is administered, the HBsAg triggers an immune response. It stimulates the production of antibodies specific to the hepatitis B surface antigen. These antibodies can then recognize and neutralize actual Hepatitis B virus particles if exposure occurs, thus providing protection against Hepatitis B infection. The immune system's memory cells also retain information about the antigen, allowing for a rapid and robust response if the individual is exposed to the virus in the future.

Hepatitis B vaccine

Injection

The following are the uses of Recombinant Hepatitis B vaccine 20 injection:

• Used for preventing Hepatitis B infections and its complications
• Used for long-term protection against the hepatitis B virus
• Used for immunization in infants, children, and adults at risk
• Used for pre-exposure prophylaxis in healthcare workers and travelers
• Used for post-exposure prophylaxis after potential exposure to the virus
• Used for catch-up vaccination in individuals who missed their scheduled doses
• Used for boosting the immune response in those with previous partial vaccination

In the case of an overdose of the Recombinant Hepatitis B vaccine, it is important to remain calm and take appropriate action. While rare, potential symptoms may include mild local reactions such as redness, swelling, or pain at the injection site. In the unlikely event of severe adverse effects, seek medical advice promptly. Treatment should be symptomatic and supportive, focusing on managing any specific symptoms that may arise, ensuring the well-being of the individual involved.

In the case of a missed dose of Recombinant Hepatitis B vaccine, it is important to consult your healthcare provider for guidance. They will determine the appropriate course of action, which may involve administering the missed dose as soon as possible or adjusting the vaccination schedule to ensure maximum protection. Depending on the timing and circumstances of the missed dose, your healthcare provider may recommend rescheduling the vaccination or simply continuing with the next scheduled dose. It is crucial to follow their advice to maintain the vaccine's effectiveness.

To administer the Recombinant Hepatitis B vaccine 20 injection, clean the injection site with an alcohol swab, insert the needle into the muscle, inject the vaccine slowly, and then safely dispose of the used needle and syringe after withdrawing the needle.

Following are the conditions or situations when Recombinant Hepatitis B vaccine should not be administered:

• Not recommended for individuals with a history of severe allergic reactions to yeast or any component of the vaccine.
• Contraindicated in individuals who have shown hypersensitivity or had a severe allergic reaction to a previous dose of hepatitis B vaccine.
• Should not be administered to individuals with a known severe allergy to medications or substances that may be used during the vaccination process (e.g., latex).
• Not suitable for individuals with a moderate or severe acute illness; it is advisable to postpone vaccination until the condition improves.
• Not recommended for individuals with a history of chronic liver disease or those currently experiencing acute liver disease, as the vaccine's effectiveness may be reduced.

The side effects of Recombinant Hepatitis B vaccine 20 injection may include:

• Pain, swelling, redness, or itching at the injection site
• Low-grade fever
• Fatigue
• Headache
• Dizziness
• Nausea
• Muscle or joint pain
• Loss of appetite

Following are the precautions and warnings for Recombinant Hepatitis B vaccine:

• Not recommended for individuals with a history of severe allergic reactions to yeast or any component of the vaccine.
• Patients with bleeding disorders or those on anticoagulant therapy should exercise caution, as injection site bleeding may occur.
• Individuals with a compromised immune system, such as HIV/AIDS patients or those receiving immunosuppressive therapy, may not achieve full protection from the vaccine.
• Ensure that the vaccine is administered intramuscularly and not intravenously or intradermally.
• Do not inject into blood vessels or nerves; take care to avoid accidental injection into these structures.
• Discontinue use and seek medical attention if any severe allergic reaction or other adverse event occurs after vaccination.
• This vaccine is intended for prevention and should not be used to treat active Hepatitis B infections.
• Consult a healthcare professional before vaccination if you have any underlying medical conditions or are taking any medications.

Following are the drug interactions for Recombinant Hepatitis B Vaccine 20 Injection:

• No significant drug interactions have been reported with this vaccine, but it is recommended to inform healthcare providers of all medications being taken.
• Avoid immunosuppressive drugs as they may reduce the immune response to the vaccine.
• Concomitant use with other vaccines can be considered; however, they should be administered at different injection sites.
• Anticoagulant medications may increase the risk of bleeding at the injection site.
• Live vaccines should not be given concurrently, as the immune response to the hepatitis B vaccine may be reduced.
• Immunoglobulins or blood products may interfere with the vaccine's effectiveness and should be administered with caution.
• Therapeutic radiation or chemotherapy may decrease the efficacy of the vaccine.

Following are the food interactions for Recombinant Hepatitis B Vaccine:

• No specific food interactions are reported with this vaccine. However, maintaining a healthy diet is essential to support the immune system's response to the vaccine.
• Staying well-hydrated and eating a balanced diet rich in fruits, vegetables, whole grains, and lean proteins can help ensure your body is prepared for the vaccination.
• There is no need to avoid any particular food or beverage before or after receiving the Recombinant Hepatitis B Vaccine.
• Some healthcare providers may recommend avoiding alcohol close to the vaccination time, as it may potentially interfere with the immune response, but this is not a direct interaction with the vaccine.
• Certain foods rich in antioxidants and vitamins, such as berries, citrus fruits, and leafy greens, can support overall immune function, which may indirectly benefit the vaccine's effectiveness.
• It is generally advisable to maintain a healthy diet and lifestyle to ensure the best response to any vaccination, including the Recombinant Hepatitis B Vaccine.
• If you have specific dietary concerns or restrictions, consult your healthcare provider for personalized advice regarding any potential food interactions.

Storage and disposal of Recombinant Hepatitis B vaccine 20 injections require careful attention. Store the vaccine in a refrigerator at 2-8°C (35-46°F), ensuring it remains protected from light. Do not freeze the vaccine as it may affect its potency. Always check the expiration date before use and discard any expired or unused injections according to local regulations. Proper disposal is crucial to prevent contamination and environmental harm; do not dispose of in regular trash or pour down the drain. Consult healthcare professionals or local waste management authorities for guidance on safe disposal methods, ensuring compliance with regulations to protect public health and the environment. Keep the vaccine out of children's reach to prevent accidental exposure.

Following are the quick tips for Recombinant Hepatitis B vaccine:

• Ensure the vaccine is stored and transported at the correct temperature, typically between 2°C and 8°C.
• Check the expiration date before administration and do not use if expired.
• Always use a new, sterile needle and syringe for each injection.
• Inject the vaccine intramuscularly into the deltoid muscle of the upper arm.
• Do not inject intravenously or subcutaneously.
• After injection, safely dispose of used needles and syringes in a designated sharps container.
• Report any adverse reactions or side effects to your healthcare provider.