Androcur (10mg) 45 Tablets

Cyproterone acetate, the active ingredient in the 10mg tablet, acts as a potent anti-androgen. Its primary mechanism of action involves competitively binding to androgen receptors, thereby blocking the effects of androgens like testosterone and dihydrotestosterone (DHT). By doing so, cyproterone acetate inhibits the activation of androgen-responsive genes, which is crucial in suppressing the androgen-dependent processes in the body. This anti-androgenic effect is particularly significant in the treatment of androgen-sensitive conditions, as it helps to reduce the impact of androgens on target tissues. Additionally, cyproterone acetate may also exhibit progestogenic activity, further contributing to its therapeutic effects in certain medical applications.

Cyproterone acetate 10mg

Antiandrogen, Progestin

Tablet

The following are the uses of Cyproterone acetate 10mg Tablet:

• Used for treating severe acne in women when other treatments have failed.
• Used to manage overactive adrenal glands in women, helping to reduce excessive hair growth and regulating irregular periods.
• Effective for managing feminizing hormone therapy in male-to-female transgender individuals.
• Used to treat advanced prostate cancer by blocking the effects of male hormones.
• Can help reduce sexual drive in men with paraphilias, under strict medical supervision.
• Used for endometriosis treatment, reducing pain and managing symptoms.
• Helps manage heavy menstrual bleeding by regulating hormonal imbalances.

In the case of an overdose of Cyproterone Acetate 10mg Tablets, individuals may experience symptoms such as dizziness, fatigue, and gastrointestinal issues. The severity of the effects can vary depending on the amount ingested. It is important to promptly contact a healthcare professional or a poison control center for guidance. They will provide specific instructions for managing the overdose, which may include inducing vomiting or administering activated charcoal to prevent further absorption. Timely intervention is crucial to ensure the best possible outcome.

In the case of a missed dose of Cyproterone Acetate 10mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen. Consult your healthcare provider if you have any concerns or questions about managing missed doses.

To take Cyproterone acetate 10mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, following the exact dosage instructions provided by your healthcare professional, ensuring you do not crush or chew the tablet.

Here are the conditions or situations when Cyproterone Acetate 10mg Tablet should not be used:

• Not recommended for individuals with a known allergy or hypersensitivity to Cyproterone Acetate or any of its excipients.
• Contraindicated in women who are pregnant or planning to become pregnant, as it can cause harm to the developing fetus.
• Should not be used by women who are breastfeeding, as it can pass into breast milk and may harm the nursing infant.
• Not suitable for individuals with severe liver disease or liver impairment, as it can affect liver function.
• Should be avoided by patients with a history of depression or mood disorders, as it may exacerbate these conditions.
• Contraindicated in patients with a history of blood clots or thrombosis, as it can increase the risk of blood clot formation.
• Not recommended for individuals with uncontrolled high blood pressure (hypertension).
• Should not be used in patients with adrenal insufficiency or adrenal gland disorders.
• Avoid using this medication if you have a history of breast cancer or any other hormone-sensitive cancer.
• Cyproterone Acetate is not suitable for individuals with rare hereditary problems of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.

The side effects of Cyproterone Acetate 10mg Tablet may include:

• Weight gain
• Mood changes or depression
• Decreased libido or sexual dysfunction
• Fatigue or drowsiness
• Nausea or upset stomach
• Headache
• Hot flashes or sweating
• Breast tenderness or enlargement
• Changes in menstrual cycle for women
• Liver enzyme changes or liver dysfunction with prolonged use

Following are the precautions and warnings for Cyproterone Acetate 10mg Tablet:

• This medication is intended for short-term use only and should not be taken for extended periods without medical supervision.
• Cyproterone acetate can cause liver damage; regular monitoring of liver function is necessary during treatment.
• It may increase the risk of blood clots, especially in individuals with a history of thrombosis or risk factors such as obesity, smoking, or certain medical conditions.
• Patients should be regularly monitored for signs of depression or mood changes, and any such symptoms should be reported to a healthcare professional.
• Not recommended for use in children and adolescents, as it may affect bone development and growth.
• Individuals with a history of or risk factors for breast cancer should exercise caution and consult a doctor before use.
• Women taking this medication should use effective contraception to prevent pregnancy, as it can cause fetal harm.

Following are the drug interactions for Cyproterone Acetate 10mg Tablet:

• Cyproterone acetate can interact with hormonal medications like oral contraceptives, potentially reducing the effectiveness of both drugs.
• It may increase the effects of anticoagulants, requiring close monitoring of blood clotting parameters.
• Cyproterone acetate can enhance the sedative effects of central nervous system depressants, such as benzodiazepines and opioids.
• Antifungal medications like ketoconazole may increase the levels of cyproterone acetate, leading to potential side effects.
• Barbiturates can reduce the effectiveness of cyproterone acetate by increasing its metabolism.
• The effectiveness of corticosteroids may be reduced when used with cyproterone acetate.
• Caution is advised when combining with antihypertensive drugs, as it may affect blood pressure regulation.
• Cyproterone acetate may interact with certain antiretroviral medications used for HIV treatment.

Following are the food interactions for Cyproterone Acetate 10mg Tablet:

• Grapefruit and grapefruit juice should be avoided as they may interfere with the metabolism of Cyproterone Acetate, potentially leading to increased drug levels in the body and a higher risk of side effects.
• Alcohol consumption should be minimized or avoided. Alcohol can enhance the sedative effects of this medication, causing increased drowsiness and dizziness.
• High-fat meals can slightly decrease the absorption of Cyproterone Acetate, but this effect is generally not clinically significant.
• Caffeine-rich foods and beverages may interact with the medication, potentially increasing heart rate and blood pressure. It's advisable to limit caffeine intake.
• Avoid excessive salt intake, as Cyproterone Acetate can cause sodium and fluid retention, which may exacerbate conditions like hypertension.
• It's advisable to maintain a balanced diet and monitor potassium levels, as this medication can sometimes cause potassium loss. Include potassium-rich foods like bananas, oranges, and spinach.
• Consult a healthcare professional about potential dietary restrictions or recommendations specific to your medical history and condition.

Cyproterone Acetate 10mg Tablets should be stored in a secure and dry location, away from direct sunlight and moisture. Keep the tablets in their original packaging, ensuring the container is tightly sealed to maintain their integrity and effectiveness. It is crucial to store the medication at room temperature, avoiding extreme temperatures, such as those found near heating appliances or in bathrooms, as these conditions can degrade the tablets. Always check the expiration date, and if the tablets are expired or no longer needed, proper disposal is essential. Do not dispose of them in wastewater or trash; instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Cyproterone Acetate 10mg Tablet:

• Take the tablet as directed by your doctor, typically once or twice daily with or after meals.
• Consistency is key; take the tablet at the same time each day for optimal results.
• Swallow the tablet whole with a full glass of water for easy swallowing.
• Avoid crushing, chewing, or breaking the tablet, unless advised by your doctor.
• If you experience mild nausea, taking the tablet with food can help.
• Inform your doctor if you have any liver or kidney issues before taking this medication.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.