Arbi (150mg) 10 Tablets

Irbesartan, the active ingredient in Irbesartan 150mg Tablets, acts as a selective antagonist of the angiotensin II type 1 (AT1) receptor. Angiotensin II is a potent vasoconstrictor hormone that plays a key role in the renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure and fluid balance in the body. By blocking the AT1 receptors, Irbesartan prevents the binding of angiotensin II, thereby inhibiting its effects. This leads to vasodilation, reduced blood pressure, and decreased strain on the heart. Irbesartan's mechanism of action helps to relax blood vessels, enhance blood flow, and ultimately lower blood pressure without affecting heart rate.

Irbesartan 150mg

Angiotensin II Receptor Blocker

Tablet

The following are the uses of Irbesartan 150mg Tablet:

• Used for treating high blood pressure (hypertension).
• Used to reduce the risk of stroke, heart attack, and heart-related deaths in patients with high blood pressure and enlarged heart.
• Used in managing diabetic kidney disease by slowing its progression and reducing related complications.
• Used to improve kidney function and delay the need for dialysis or kidney transplant.
• Used for reducing protein loss in urine, a marker of kidney damage.
• Used as part of a comprehensive treatment plan for cardiovascular and renal health.
• Used to improve overall cardiovascular health and lower the risk of heart-related events.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Hypertension- Take 150mg once daily.
• Coronary artery disease- Take 150mg once daily.
• Stroke- Take 150mg once daily.
• Heart failure- Take 150mg once daily.

In the case of an overdose of Irbesartan 150mg Tablets, individuals may experience symptoms such as dizziness, low blood pressure, increased heart rate, and kidney problems. It is important to recognize that the severity of these symptoms can vary based on the amount ingested. If a person suspects an overdose, they should seek medical advice promptly. Timely intervention and supportive care are crucial in managing the potential adverse effects and ensuring the well-being of the individual.

In the case of a missed dose of Irbesartan 150mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely adjust your medication regimen. It's always best to maintain a consistent schedule, but if a dose is missed, take appropriate action without delay.

To take Irbesartan 150mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, as directed by your healthcare provider, usually once daily with or without food.

Irbesartan 150mg Tablet should not be used in the following conditions:

• Must not be taken by individuals with a known allergy or hypersensitivity to Irbesartan or any other angiotensin II receptor blockers (ARBs).
• Not suitable for patients with severe liver disease or biliary obstruction.
• Should be avoided during pregnancy or breastfeeding.
• Not recommended for children below 18 years of age.
• Contraindicated in patients with bilateral renal artery stenosis or unilateral renal artery stenosis in a solitary kidney.
• Should not be used in patients with severe vomiting, diarrhea, or dehydration due to risk of blood pressure drop.
• Not suitable for individuals with a history of angioedema, especially associated with previous use of ACE inhibitors or ARBs.

The side effects of Irbesartan 150mg Tablet may include:

• Dizziness
• Fatigue or weakness
• Headache
• Diarrhea
• Nausea and vomiting
• Muscle cramps
• Increased potassium levels in the blood (hyperkalemia)
• Elevated liver enzymes

Following are the precautions and warnings for Irbesartan 150mg Tablet:

• Not recommended for individuals with a known allergy to Irbesartan or other angiotensin II receptor blockers.
• Patients with a history of liver problems should exercise caution, as Irbesartan may affect liver function. Regular monitoring is advised.
• Dehydration risk is increased with Irbesartan, especially in those with low blood pressure or taking diuretics. Ensure adequate fluid intake.
• May cause dizziness or lightheadedness, particularly when standing up from a sitting or lying position. Rise slowly to prevent falls.
• Diabetic patients should be cautious as Irbesartan may affect blood sugar levels. Monitor blood glucose regularly.
• Not recommended during pregnancy or breastfeeding unless clearly needed. Consult a doctor for alternative options.
• Elderly patients may be more sensitive to the effects of Irbesartan. Regular monitoring is advised for potential side effects.

Following are the drug interactions for Irbesartan 150mg Tablet:

• Concomitant use with ACE inhibitors (e.g., enalapril) or other angiotensin II receptor antagonists (ARBs) may increase the risk of hyperkalemia and renal impairment.
• Diuretics (e.g., furosemide) may enhance the blood pressure-lowering effects of Irbesartan, increasing the risk of hypotension, especially during the initial stages of therapy.
• Lithium levels may increase when used together with Irbesartan, leading to a risk of lithium toxicity. Close monitoring of lithium levels is recommended.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen, naproxen) can reduce the effectiveness of Irbesartan and may increase the risk of kidney damage, especially in patients with pre-existing kidney problems.
• Potassium-sparing diuretics (e.g., spironolactone) or potassium supplements may increase the risk of hyperkalemia when used with Irbesartan.
• Aliskiren, a direct renin inhibitor, should not be used in combination with Irbesartan in patients with diabetes or renal impairment due to the increased risk of hyperkalemia, hypotension, and kidney dysfunction.
• Corticosteroids (e.g., prednisone) and NSAIDs can exacerbate fluid retention and impair the antihypertensive effect of Irbesartan.
• Antihypertensive medications, including beta-blockers (e.g., metoprolol), may increase the blood pressure-lowering effect of Irbesartan, possibly leading to hypotension.
• Rifampin, a potent inducer of liver enzymes, may decrease the effectiveness of Irbesartan by increasing its metabolism.

Following are the food interactions for Irbesartan 150mg Tablet:

• Irbesartan can be taken with or without food, but it is best to maintain a consistent routine for optimal absorption.
• Grapefruit and grapefruit juice should be consumed with caution as they may increase the blood levels of Irbesartan, leading to a potential increase in side effects.
• Alcohol may slightly increase blood pressure-lowering effects, but moderate consumption is generally considered safe.
• High-salt foods should be limited as Irbesartan may cause increased sensitivity to salt, affecting blood pressure control.
• Potassium-rich foods like bananas, oranges, and spinach are beneficial, but excessive intake should be monitored to prevent high potassium levels.
• A balanced diet low in saturated fats and cholesterol is recommended to support cardiovascular health.
• Avoid excessive use of licorice as it may decrease the effectiveness of Irbesartan by reducing its absorption.
• Staying well-hydrated is essential, especially for individuals with kidney problems, as Irbesartan can affect kidney function.

Irbesartan 150mg Tablets should be stored in a cool, dry area, ideally at room temperature, ensuring protection from light and moisture. It is crucial to keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. Avoid storing them in the bathroom or near heat-emitting appliances, as temperature fluctuations can impact the medication's effectiveness. Regularly check the expiration date, and if the tablets are no longer needed or have expired, do not flush them or dispose of them via household drains. Consult your pharmacist or healthcare provider for guidance on safe disposal methods. It is imperative to keep all medications securely stored and out of the reach of children to prevent accidental consumption.

Following are the quick tips for Irbesartan 150mg Tablet:

• Take the tablet as directed by your doctor, usually once daily.
• Consistency is key; take it at the same time each day.
• Can be taken with or without food, but be consistent.
• Swallow the tablet whole with a full glass of water.
• If you have difficulty swallowing, ask your pharmacist about alternative options.
• Do not crush or chew the tablet, as it may affect its effectiveness.
• Regular blood pressure monitoring is essential while taking this medication.

When taking Irbesartan, it is important to prioritize your health and monitor the effectiveness of the medication, ensuring it does not cause any adverse effects. To do so, it is necessary to undergo regular lab tests, including liver function tests, cholesterol tests, and blood pressure checks. These tests play a crucial role in monitoring the drug's effectiveness and checking for any potential liver problems or increased cholesterol levels, which are known side effects of the drug.These regular blood pressure tests provide valuable insight into the medication's effectiveness in lowering your blood pressure to a target range. These tests are crucial in ensuring the safety and efficacy of the medication for you. Based on the results, your doctor can make informed decisions about any necessary adjustments to the dosage. Overall, monitoring your health while taking Irbesartan is essential to ensure that the medication works effectively and safely, and regular lab tests and blood pressure checks are key components of this process.