Arceva DS (15/90mg) 30ml Dry Suspension

Malaria is a disease that affects many people worldwide, notably in Africa. To treat this condition, there are various medications available, including the combination of Artemether 15mg + Lumefantrine 90mg. This drug combination is often used to treat Plasmodium falciparum malaria, which is most commonly found in Africa. Artemether is a derivative of Artemisinin, a substance derived from the herb Artemisia annua, or sweet wormwood. These compounds are believed to disrupt the digestion of hemoglobin by the malaria parasite, leading to the accumulation of toxic molecules in the parasite's cells, resulting in its destruction. Lumefantrine is also used to treat malaria, by inhibiting the electron transport pathway in the malaria parasite's mitochondria by blocking the polymerization of hemoglobin in the parasite's digestive vacuole. This results in the accumulation of toxic heme molecules in the parasite. These two drugs work synergistically to counteract malaria parasites by operating at various points in the malaria parasite's life cycle. It's essential to follow your doctor's instructions regarding dosage and duration of treatment. Furthermore, people should be aware that this drug combination does not inhibit the growth of the malaria parasite in the liver. As a result, it is necessary to include a third drug to kill the parasite in the liver before it can multiply and cause another infection in the red blood cells.

Powered by Froala Editor

Antimalarial

Powered by Froala Editor

Syrup/Suspension

Powered by Froala Editor

Unveiling its multifaceted uses and transformative applications as follows:

• Treatment of malaria caused by Plasmodium falciparum that is resistant to chloroquine or sulfadoxine-pyrimethamine
• Treatment of malaria in pregnancy including the first trimester
• Treatment of severe malaria
• Prevention of malaria in regions with high malaria risk

Powered by Froala Editor

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Artemether dose • 1 x 15 mg tablet per day for adults, or 0.5 x 15 mg per day for children weighing less than 15 kg or 1 x 7.5 mg per day for children weighing less than 7 kg.
• Lumefantrine dose • 1 x 90 mg tablet per day for adults or 2 x 45 mg tablets per day for children weighing more than 30 kg or 3 x 30 mg tablets per day for children weighing less than 30 kg.

Powered by Froala Editor

If an individual were to overdose on Artemether 15mg and Lumefantrine 90mg, there is no specific treatment for this reaction. Instead, the individual would need to undergo supportive treatment, which may include the following procedures:

Powered by Froala Editor

It is important that you take artemether 15mg and lumefantrine 90mg as directed and complete the full course of treatment as prescribed by your doctor. If you have missed a dose, it is essential to inform your doctor as soon as possible for guidance on how to proceed. Following your doctor's instructions is critical for achieving the best possible results from your treatment.

Powered by Froala Editor

Artemether and Lumefantrine are medications that should be taken orally, preferably during meals to mitigate chances of an upset stomach. For adults and children over 35 kg, one Artemether 15mg tablet is to be taken daily for three days. For children weighing less than 35 kg, the dose should be calculated.

Powered by Froala Editor

Discerning instances where this medication may not be appropriate:

• If you are allergic to artemether or lumefantrine, or any of the other ingredients in this medication.
• If you have severe kidney disease or anuria (complete absence of urine production). This is because artemether is excreted by the kidneys, and impaired kidney function can lead to excessive build-up of the drug, which can result in unwanted side effects.

Powered by Froala Editor

Unraveling the side effects lurking behind this medications are as follows:

• Neurotoxicity
• Anxiety
• Dizziness
• Insomnia
• Rash
• Stirred emotions
• Loss of appetite
• Nausea
• Vomiting
• Diarrhea
• Constipation
• Headache
• Tremors
• Skin rashes

Powered by Froala Editor

The warnings and precautions associated with Artemether and Lumefantrine are:

• Severe renal and hepatic impairment.
• Children.
• Pregnancy and lactation.
• Not indicated for the prevention and treatment of severe or complicated malaria.

Powered by Froala Editor

The drug interactions with artemether and lumefantrine include:

• CYP3A4 Substrates (e.g., statins) – Can increase levels of substrates.
• Anticonvulsants – Can reduce efficacy.

Powered by Froala Editor

The food interactions that should be considered while using artemether and lumefantrine are:

• Taking the product with food, especially a high-fat meal, increases absorption.

Powered by Froala Editor

When you obtain the prescription drugs of Artemether 15mg and Lumefantrine 90mg from a pharmacy, they usually come in a secure, tamper-proof container to prevent contamination and adulteration. Be sure to store these medications safely and maintain them in a cool, dry place at room temperature. They should be kept away from children's reach and protected from heat, moisture, and direct light. It's vital to adhere to the specific storage instructions on the label of the medication. Before you use these medications, it's essential to consult a healthcare professional. This is because the dosage is weight-based, and the duration of treatment may differ based on the country you live in.

Powered by Froala Editor