Artheget DS (40/240mg) 8 Tablets

Artheget DS (40/240mg) 8 Tablets

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  • Manufacturer Getz Pharma (Pvt.) Ltd.
  • Generic Name

    Artemether 40mg, Lumefantrine 240mg

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Storage/Disposal
  • Description

    Malaria is a disease caused by an infection with parasites, and Artemether and Lumefantrine are combination medicines used to treat this disease. Artemether works by interfering with the breakdown of hemoglobin in red blood cells by parasite enzymes, and Lumefantrine works by damaging the parasite's DNA, thus preventing the growth and reproduction of malaria parasites. This medication is usually taken for 3 days, starting as soon as possible after the onset of malaria symptoms to reduce the severity of these symptoms and diminish the risk of complications due to the infection. It is vital to adhere to your doctor's instructions while taking this medication to ensure effective treatment and reduce the chance of an unsuccessful treatment or recurrence of the infection.

  • Ingredients

    Artemether 40mg, Lumefantrine 240mg

  • Drug Class

    Artemether:

  • Dosage Form

    Tablet

  • Uses

    Artemether + Lumefantrine combination is utilized for the following therapeutic indications:

    • Treating uncomplicated malaria
    • Reducing symptoms associated with malaria
    • Preventing malaria complications
    • Improving overall recovery from malaria infections
    • Enhancing the effectiveness of malaria treatment when used in combination therapy
    • Decreasing the risk of malaria relapse by providing rapid action against the Plasmodium parasite
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Artemether 40mg - For treatment of malaria, the recommended dosage is 11mg per kg of body weight per day, divided into 2 doses and taken with breakfast and dinner for 3 days.
    • Artemether 40mg - For the treatment of severe malaria, the recommended dose is 20mg per kg of body weight per day, divided into 2 doses and taken with breakfast and dinner for 2 days.
    • Lumefantrine 240mg - For the treatment of malaria, the recommended dosage is 10mg per kg of body weight per day, divided into 2 doses and taken with breakfast and dinner for 7 days.
    • Lumefantrine 240mg - It is very important to take this medication exactly as prescribed and complete the full course of treatment to ensure effectiveness and prevent recurrence of the infection.
  • In case of Overdose

    If someone overdoses on Artemether 40mg and Lumefantrine 240mg, they require supportive care as there is no specific antidote for these drugs. Initially, the physician will stabilize the vital signs, including temperature, pulse, breathing rate, and blood pressure. Overdose of these drugs can cause reduced consciousness or coma, especially if there are other central nervous system (CNS) depressants present in the system. Therefore, it is crucial to maintain the airway, breathing, and circulation.In most cases, induced vomiting and bowel emptying through lavage (washing out the bowel) are not useful options for elimination as these drugs have low solubility in water. Dialysis is also not recommended. The physician will then treat any symptoms, which may include seizures, agitation, or muscle problems. Any heart issues that arise due to the overdose will also be addressed. It is essential to note that intensive monitoring in a specialized medical facility is crucial to manage any potential adverse effects or complications until recovery occurs. Immediate medical attention is critical to improve their clinical outcome, as delayed treatment may lead to severe complications or death.

  • Missed Dose

    If you miss a dose of artemether 40mg and lumefantrine 240mg, it is important to take it as soon as possible. But if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Doubling up on a missed dose unless advised could lead to overdose, so ensure you have clarity from your doctor before acting. Following the dosing schedule carefully ensures effective treatment, but if you have any questions or concerns about missing a dose, it is best to consult your physician or pharmacist for guidance on how to move forward with your treatment plan. It is important to remember that completing the full course of medication as prescribed by your physician is essential for achieving the best treatment outcomes.

  • How To Use

    Before starting to take Artemether 40mg and Lumefantrine 240mg, ensure you read the medication guide provided by your pharmacist. For any water-based medications, ensure you drink clean or boiled water. Artemether 40mg tablets should be taken whole with a glass of water, with a meal or after a meal, and snaking it with a fatty meal may increase the drug's absorption. Lumefantrine 240mg tablets should also be taken whole with a glass of water, with a meal, and at the same time each day. These tablets are usually taken in courses of 3 days with a gap of 1 week, then repeated for another 3 days. Ensure you complete the full course of medication as per your doctor's prescription. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue on your regular schedule. Do not take double the dose. Consult your doctor or pharmacist if you have any questions or concerns about your medication. It is important to store these medications at room temperature, away from light and heat. Avoid freezing, and keep these medications out of the reach and sight of children. This information is only a summary. Talk to your doctor or pharmacist before taking Artemether 40mg and Lumefantrine 240mg to ensure that you are clear on how to take this medication and that you are aware of any potential risks or side effects.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • If you are allergic to artemether or lumefantrine, or any of the other ingredients in this medication.
    • If you have severe kidney disease or an enzyme deficiency (associated with malnourishment) as this may affect the dosing. If you have moderate kidney disease you may require a lower dose.
    • If you are already taking any other medications, especially any other anti-malarials, antibiotics, or medications that affect your liver or kidneys.
    • If you have had recent surgery or you have severe bleeding problems.
    • If you are pregnant, trying to become pregnant, or breastfeeding. The effects of this medication on an unborn or breastfeeding child are not known, so it is important to talk to your doctor before taking this medication if you are pregnant or breastfeeding.
    • If you have a pre-existing congenital heart disease.
    • If you've had an episode of cerebral malaria in the past that was not treated.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Nausea
    • Vomiting
    • Loss of appetite
    • Fatigue
    • Dizziness
    • Blurred vision
    • Seizures
    • Skin rash
    • Unexplained fever
  • Storage/Disposal

    If you want to keep your antimalarial medication effective, you should store it in a cool, dry place away from direct heat, light, or moisture. Ensure it's kept at a room temperature of approximately 15-30°C and is not exposed to children. Always ensure the medication is in its original container and do not store beyond the expiration date. Following these storage instructions ensures the safety of the medication.

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