Ascard (150mg) 30 Tablets

Aspirin, also known as acetylsalicylic acid, exerts its therapeutic effects primarily through its ability to irreversibly inhibit cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. These enzymes play a crucial role in the synthesis of prostaglandins, thromboxane, and prostacyclin, which are important mediators of inflammation, pain, and fever. When aspirin is ingested, it is rapidly absorbed and hydrolyzed in the body to salicylic acid, which is the active metabolite. Salicylic acid inhibits COX enzymes by acetylating a specific amino acid residue in the enzyme's active site, preventing the production of prostaglandins and thromboxane. This inhibition leads to reduced inflammation, analgesic effects, and antipyretic actions. Additionally, aspirin's antiplatelet activity arises from its irreversible inhibition of COX-1 in platelets, disrupting the production of thromboxane A2, a potent inducer of platelet aggregation and vasoconstriction, thereby inhibiting platelet activation and aggregation, and promoting blood flow.

Aspirin

NSAID (Non-steroidal anti-inflammatory drug)

Tablet

The following are the uses of Aspirin Tablet:

• Used for relieving pain and reducing fever
• Used as an anti-inflammatory to reduce swelling and inflammation
• Used to prevent blood clots and reduce the risk of heart attacks and strokes
• Used for its antiplatelet effect, helping to prevent the formation of harmful blood clots
• Used to treat mild to moderate aches and pains, including headaches, toothaches, and muscle pain
• Used to reduce discomfort and inflammation in conditions like arthritis
• Used as a short-term remedy for minor injuries and post-operative pain

Take as per doctor's prescription

In the case of an overdose of Aspirin Tablets, several symptoms may occur, including ringing in the ears, nausea, vomiting, and abdominal pain. More severe effects can lead to rapid breathing, confusion, and even coma. It is crucial to seek medical assistance promptly if an overdose is suspected. Treatment may involve administering activated charcoal to absorb the excess medication and supportive care to manage symptoms until the drug is eliminated from the body. Timely intervention is essential to prevent potential complications.

In the case of a missed dose of Aspirin Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare provider for guidance on how to safely resume your medication regimen. It is recommended to set reminders or use a pill organizer to help you remember to take your medication as prescribed.

To take an Aspirin Tablet, swallow the tablet whole with a full glass of water, ensuring you follow the dosage instructions provided by your healthcare provider, typically one tablet every 4 to 6 hours, with the maximum daily dose not exceeding four tablets in a 24-hour period.

Following are the conditions/situations when Aspirin Tablet should be avoided or used with caution:

• Do not take if you have a known allergy to Aspirin (acetylsalicylic acid) or other salicylates, or if you have experienced asthma attacks, hives, or other allergic reactions after taking Aspirin or similar medications.
• Avoid if you have a bleeding disorder such as hemophilia, or if you are currently experiencing bleeding in the stomach or intestines.
• Should not be used in individuals with active peptic ulcer disease or a history of gastrointestinal bleeding.
• Contraindicated in children and teenagers recovering from chickenpox or flu-like symptoms, as it may increase the risk of Reye's syndrome.
• Avoid using Aspirin if you have severe liver or kidney disease.
• Do not take before any surgery, including dental procedures, as it can increase bleeding risk.
• Not recommended for individuals with uncontrolled high blood pressure.
• Should be used with caution in individuals with asthma, as it may trigger bronchospasm.
• Avoid using Aspirin if you are in the third trimester of pregnancy.

The side effects of Aspirin Tablet may include:

• Stomach pain or discomfort
• Nausea and vomiting
• Heartburn
• Bleeding or bruising
• Allergic reactions (such as rash, itching, or swelling)
• Ringing in the ears (tinnitus)
• Dizziness or vertigo
• Increased sensitivity to light

Following are the precautions and warnings for Aspirin Tablet:

• Aspirin should not be used in individuals with a known allergy to salicylates or non-steroidal anti-inflammatory drugs (NSAIDs).
• This medication can cause gastrointestinal bleeding, especially in those with a history of stomach ulcers or gastrointestinal bleeding.
• Aspirin may increase the risk of bleeding disorders and should be used with caution in patients with bleeding tendencies or those on anticoagulant therapy.
• It can worsen asthma symptoms in some individuals, so asthma patients should use it with caution.
• Kidney function should be monitored during long-term use, as aspirin can affect kidney health.
• Not recommended for use in children and adolescents under 16 years of age for fever or pain management due to the risk of Reye's Syndrome.
• Pregnant and breastfeeding women should consult their doctor before taking Aspirin, as it can affect fetal development and pass into breast milk.

Following are the drug interactions for Aspirin Tablet:

• Aspirin may interact with other nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, increasing the risk of gastrointestinal bleeding and ulcers.
• When taken with anticoagulants/antiplatelet agents such as warfarin or clopidogrel, aspirin can further enhance their anticoagulant effects, requiring close monitoring.
• Using aspirin with angiotensin-converting enzyme (ACE) inhibitors may lead to reduced ACE inhibitor efficacy and increased risk of kidney dysfunction.
• The risk of bleeding can be increased when aspirin is combined with selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs).
• Aspirin may decrease the effectiveness of diuretics, particularly loop diuretics, by inhibiting their renal excretion.
• Using aspirin with corticosteroids may increase the risk of gastrointestinal bleeding.
• Combining aspirin with methotrexate can increase methotrexate levels, potentially leading to toxicity.

Following are the food interactions for Aspirin Tablet:

• Avoid excessive alcohol consumption as it can increase the risk of gastrointestinal bleeding when combined with Aspirin.
• Grapefruit and grapefruit juice should be limited as they may affect Aspirin's metabolism, altering its effectiveness.
• Avoid high-sodium foods, as Aspirin can increase sodium retention, potentially affecting blood pressure.
• Avoid large amounts of Vitamin K-rich foods like leafy greens, as Aspirin can interfere with Vitamin K absorption, impacting blood clotting.
• Limit caffeine intake, as it can enhance Aspirin's effects on blood thinning, increasing bleeding risks.
• Fatty foods may delay Aspirin absorption, so it's best to take it on an empty stomach or with a light meal.
• Avoid large doses of fish oil supplements, as they may increase bleeding risks when combined with Aspirin.

Aspirin tablets should be stored in a cool, dry place, preferably at room temperature, ensuring they are kept away from direct sunlight, moisture, and heat sources like radiators or stoves, as these conditions can degrade the medication. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. It's crucial to dispose of any unused or expired aspirin tablets responsibly; do not flush them or pour them down the drain. Consult your pharmacist or healthcare provider for appropriate disposal methods in your area. Always keep medicines out of children's reach to prevent accidental consumption. Regularly check the packaging for the expiration date, discarding any tablets that have passed this date to ensure safety and efficacy.

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Following are the quick tips for Aspirin Tablet:

• Consult your doctor before use, especially if you have allergies or medical conditions.
• Take the tablet with food or after meals to prevent stomach irritation.
• Swallow the tablet whole; do not crush or chew it.
• Maintain a consistent dosing schedule for maximum effectiveness.
• Avoid alcohol consumption while taking aspirin to reduce the risk of stomach bleeding.
• Inform your doctor about all medications you are taking to prevent interactions.
• Store aspirin tablets in a cool, dry place away from direct sunlight and moisture.