Atizor (500mg) 6 Tablets

Atizor (500mg) 6 Tablets

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  • Manufacturer Hiranis Pharmaceuticals (Pvt.) Ltd.
  • Generic Name

    Azithromycin 500mg

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4.9/ 5
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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Laboratory Screening
  • Description

    Azithromycin 500mg Tablet's primary mechanism of action is centered on its ability to inhibit bacterial protein synthesis. It achieves this by binding to the 50S subunit of bacterial ribosomes, which subsequently prevents the translocation of aminoacyl tRNA. This action leads to the disruption of bacterial protein synthesis, thereby halting the growth and multiplication of susceptible bacteria. This antibiotic is particularly effective against a wide range of bacteria, including Gram-positive and Gram-negative organisms, by interfering with their ability to produce essential proteins.

  • Ingredients

    Azithromycin 500mg

  • Drug Class

    Macrolide antibiotic.

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Azithromycin 500mg Tablet:

    • Used for treating bacterial infections such as pneumonia, bronchitis, and sinusitis.
    • Used for curing severe skin infections and wound infections.
    • Used for the treatment of sexually transmitted diseases like gonorrhea.
    • Used for preventing and treating Mycobacterium Avium Complex (MAC) infections.
    • Used for managing middle ear infections (otitis media) in children.
    • Used for controlling infections in the gastrointestinal tract, such as traveler's diarrhea.
    • Used for the management of certain types of urinary tract infections.
    • Used for reducing flare-ups of chronic obstructive pulmonary disease (COPD).
  • Dosage

    Dose must be taken according to doctor’s advice only; doses given below are suggested as supportive literature for better understanding in some areas of requirements. Adult dose: 500mg once daily or 250mg twice daily For typhoid fever, the dose is 500mg to 1000mg once daily for 5-7 days. Oral dose for Infants, Children over 6 months, and Adolescents: 5 to 12 mg/kg/dose, typically administered as 10 to 12 mg/kg/dose on a day while usual maximum dose is 500mg/dose Followed by 5-6 mg/kg once daily (usual maximum dose: 250 mg/dose).
  • In case of Overdose

    In the case of an overdose of Azithromycin 500mg Tablets, individuals may experience a range of symptoms. These can include gastrointestinal issues such as nausea, vomiting, and abdominal pain. Overdose may also lead to neurological effects like dizziness, headache, and, in severe cases, seizures. Prompt medical intervention is necessary to manage these symptoms effectively and ensure appropriate treatment to prevent potential complications. It is crucial to seek medical advice if an overdose is suspected.

  • Missed Dose

    In the case of a missed dose of Azithromycin 500mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one. Do not double the dose to make up for a missed dose. If you have missed multiple doses, consult your healthcare provider for guidance on how to resume your medication schedule. It is recommended to take the missed dose within 24 hours of the scheduled time to maintain the effectiveness of the treatment. Always keep a consistent dosing schedule to ensure the best therapeutic outcome.

  • How To Use

    To take Azithromycin 500mg Tablet, swallow the tablet whole with a full glass of water, preferably on an empty stomach, once daily, as directed by your healthcare professional, ensuring you complete the full course of medication as prescribed.

  • When Not to Use

    Here are the conditions and situations when Azithromycin 500mg Tablet should not be taken:

    • Avoid using this medication if you have a known allergy to Azithromycin or any macrolide-type antibiotics.
    • Do not take this medicine if you have a history of liver or kidney problems.
    • Contraindicated in individuals with a prolonged QT interval or heart rhythm disorders.
    • Should not be used in patients with myasthenia gravis.
    • Not suitable for individuals with a history of jaundice or liver dysfunction caused by previous azithromycin use.
    • Avoid using this medication if you have a history of arrhythmias (irregular heart rhythms).
    • Do not administer to infants with esophageal or upper gastrointestinal narrowing or perforation.
  • Side Effects

    The side effects of Azithromycin 500mg Tablet may include:

    • Nausea and vomiting
    • Diarrhea
    • Abdominal pain
    • Headache
    • Dizziness
    • Skin rashes or itching
    • Fatigue and weakness
    • Abnormal liver function tests
  • Precautions & Warnings

    Following are the precautions and warnings for Azithromycin 500mg Tablet:

    • Not recommended for individuals with known allergies to Azithromycin or similar antibiotics like erythromycin.
    • Patients with existing liver or kidney disease should use with caution, and regular monitoring is advised.
    • May cause dizziness or lightheadedness; patients should avoid driving or operating machinery if affected.
    • Caution is advised for elderly patients as they may be more susceptible to side effects.
    • Not recommended for prolonged use, and unnecessary use should be avoided to prevent antibiotic resistance.
    • May interact with other medications; inform your doctor about all medicines you are taking.
    • Pregnant and breastfeeding women should consult a healthcare professional before taking this medication.
  • Drug Interactions

    Following are the drug interactions for Azithromycin 500mg Tablet:

    • Antacids containing aluminum or magnesium can reduce the absorption of Azithromycin, so they should not be taken simultaneously.
    • Concomitant use with Nelfinavir, a protease inhibitor, can increase the risk of cardiac side effects and should be avoided.
    • Azithromycin may increase the concentration of Digoxin, thus requiring close monitoring of Digoxin levels.
    • Theophylline levels can be increased when used with Azithromycin, potentially leading to Theophylline toxicity.
    • Ergotamine and dihydroergotamine interactions with Azithromycin can cause ergot toxicity, so their combined use should be avoided.
    • Warfarin and other anticoagulants may have altered effects when taken with Azithromycin, requiring close monitoring of coagulation parameters.
    • Caution is advised when using Azithromycin with statins, as it may increase the risk of muscle-related side effects, including rhabdomyolysis.
  • Food Interactions

    Following are the food interactions for Azithromycin 500mg Tablet:

    • Avoid consuming grapefruit or grapefruit juice during the treatment period, as it can lead to increased levels of the drug in the body and potentially cause adverse effects.
    • Alcohol intake should be minimized or avoided as it may worsen side effects like nausea and gastrointestinal discomfort.
    • Consuming a full meal, especially fatty foods, just before or after taking the tablet may reduce its absorption. It is recommended to take the medication on an empty stomach.
    • Dairy products like milk, cheese, or yogurt may interfere with the absorption of Azithromycin. Avoid taking the tablet with these products.
    • Avoid caffeine-rich beverages like coffee or energy drinks, as they may increase the metabolism of Azithromycin, reducing its effectiveness.
    • Ensure adequate hydration during the course of treatment to support the body's response to the medication.
    • Avoid high-fat meals, as they can delay the absorption of Azithromycin, potentially reducing its effectiveness.
    • Maintain a balanced diet to support overall health and recovery during the antibiotic treatment.
  • Storage/Disposal

    Azithromycin 500mg Tablets should be stored in a cool and dry place, preferably at room temperature, away from direct exposure to sunlight or moisture. Keep the tablets in their original packaging or container, tightly sealed, to maintain their integrity and prevent contamination. It is crucial not to store the medication in the bathroom or near heat sources, as extreme temperatures can degrade its quality. Always check the expiration date, and if the tablets have expired, dispose of them properly by consulting a pharmacist or healthcare professional for safe disposal practices. Never flush medications down the toilet or sink; instead, follow local guidelines for pharmaceutical waste disposal. Ensure that the tablets are kept out of children's reach to prevent accidental consumption.

  • Quick Tips, if any

    Following are the quick tips for Azithromycin 500mg Tablet:

    • Take the tablet as directed by your doctor, usually once daily.
    • Ensure you complete the full prescribed course, even if you feel better early on.
    • Swallow the tablet whole with a full glass of water; do not crush or chew.
    • Take the tablet on an empty stomach, preferably 1 hour before or 2 hours after a meal.
    • Avoid taking antacids or dairy products within 2 hours of taking this medication.
    • Inform your doctor if you have any allergies or medical conditions before starting this medication.
    • Store the tablets at room temperature, away from moisture and light.
  • Laboratory Screening

    To confirm microbial infections, go for; Blood Culture Test. In order to confirm typhoid fever, go for; TyphiDot (IgM) Test. In case of abnormal heart rhythm due to azithromycin use, go for; CT- scan.

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