AURORIX IMP 150MG TAB 30'S

Moclobemide 150MG Tablet primarily exerts its therapeutic effects through reversible inhibition of monoamine oxidase type A (MAO-A). By inhibiting MAO-A, moclobemide blocks the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. This inhibition leads to increased levels of these neurotransmitters in the synaptic cleft, enhancing their availability for signaling between neurons. Moclobemide's selectivity for MAO-A results in fewer dietary restrictions compared to non-selective MAO inhibitors, as it does not significantly inhibit the metabolism of tyramine, thus reducing the risk of hypertensive crises associated with dietary tyramine intake.

MAO inhibitor.

Tablet

The following are the uses of Moclobemide 150MG Tablet:

• Used for treating depression and improving mood by increasing certain brain chemicals.
• Used for enhancing motivation and energy levels, helping patients feel more active.
• Used to reduce anxiety and nervousness, promoting a sense of calmness.
• Used to improve concentration and mental focus, aiding in better cognitive function.
• Used for managing social anxiety disorder, making social interactions easier.
• Used to alleviate panic attacks and their frequency, providing relief from intense fear.
• Used to restore interest in daily activities and hobbies, improving overall well-being.
• Used for maintaining a positive mindset and preventing depressive episodes.

In the case of an overdose of Moclobemide 150MG Tablets, it is important to recognize the potential severity of the situation. Symptoms may include severe nausea, vomiting, seizures, and even loss of consciousness. Prompt medical intervention is vital. If you suspect an overdose, contact a healthcare professional or emergency services immediately. Quick action can help prevent serious health complications and ensure the best possible outcome.

In the case of a missed dose of Moclobemide 150MG Tablet, it is recommended to take the missed dose as soon as you remember, provided there is a sufficient gap before the next scheduled dose. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare provider for guidance on how to get back on track with your medication regimen.

To take Moclobemide 150MG Tablet, swallow the tablet whole with a glass of water, preferably in the morning or as directed by your healthcare professional, following the prescribed dosage and duration for optimal effectiveness.

Following are the conditions or circumstances when Moclobemide 150MG Tablet should not be taken:

• Must not be taken by individuals with a known allergy or hypersensitivity to Moclobemide or any of its excipients.
• Contraindicated in patients with pheochromocytoma, a rare tumor of the adrenal gland.
• Not suitable for individuals with severe liver disease or impairment.
• Should not be used in patients with manic-depressive disorders or bipolar disorder.
• Contraindicated during seizure disorders or active seizure conditions.
• Must be avoided by individuals with a history of blood disorders or conditions affecting blood clotting.
• Not recommended for patients with a history of glaucoma.
• Should not be taken by individuals with a history of brain injury or increased intracranial pressure.
• Contraindicated in patients with a history of drug abuse or dependence.

The side effects of Moclobemide 150MG Tablet may include:

• Dizziness
• Headache
• Nausea
• Insomnia (difficulty sleeping)
• Dry mouth
• Constipation
• Anxiety or restlessness
• Skin rash or itching

Here are the precautions and warnings for Moclobemide 150MG Tablet:

• Moclobemide may cause drowsiness or dizziness, so patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Not recommended for individuals with a history of hypersensitivity or allergic reactions to moclobemide or any of its excipients.
• Patients with a history of liver or kidney disease should be monitored closely, as dosage adjustments might be necessary.
• Moclobemide should be used with caution in patients with a history of seizures, as it may lower the seizure threshold.
• It is important to avoid alcohol consumption while taking Moclobemide as it may increase the risk of side effects.
• Patients with a history of bipolar disorder should be closely monitored, as moclobemide may induce manic episodes.
• The use of Moclobemide during pregnancy and breastfeeding should be discussed with a healthcare professional, as the potential risks and benefits need to be carefully considered.
• Discontinuation of Moclobemide should be gradual to minimize the risk of withdrawal symptoms.

Following are the drug interactions for Moclobemide 150MG Tablet:

• Moclobemide may increase serotonin levels when combined with selective serotonin reuptake inhibitors (SSRIs), leading to serotonin syndrome, a potentially serious condition.
• It should not be taken with monoamine oxidase inhibitors (MAOIs) due to the risk of severe adverse reactions, including hypertensive crisis.
• Moclobemide can interact with anticoagulants like warfarin, possibly requiring a reduction in the anticoagulant dose to maintain the desired effect.
• The use of Moclobemide with other central nervous system (CNS) depressants, including alcohol, benzodiazepines, and opioids, can enhance sedation and impair cognitive function.
• It may increase the effects of certain antihypertensive medications, such as beta-blockers and calcium channel blockers, leading to excessive blood pressure reduction.
• Moclobemide can elevate the levels of phenytoin, a commonly used anticonvulsant, requiring close monitoring of phenytoin concentrations.
• Caution is advised when combining Moclobemide with drugs that induce or inhibit liver enzymes, as this may affect the metabolism and effectiveness of Moclobemide.

Following are the food interactions for Moclobemide 150MG Tablet:

• Moclobemide should be taken with food to enhance its absorption, particularly with high-fat meals, as it can increase the bioavailability of the medication.
• Grapefruit and grapefruit juice consumption should be avoided as they can inhibit the CYP1A2 enzyme, leading to increased levels of Moclobemide in the body and potentially causing adverse effects.
• Alcohol consumption should be limited or avoided during treatment with Moclobemide as it may enhance the sedative effects of the medication, increasing the risk of dizziness and drowsiness.
• Caffeine intake should be monitored as it can affect serotonin levels in the brain, and excessive caffeine may counteract the therapeutic effects of Moclobemide.
• Tyramine-rich foods like aged cheeses, cured meats, and fermented products should be consumed with caution as Moclobemide may interact with tyramine, leading to a potential increase in blood pressure.
• Avoid high-sodium foods as Moclobemide may cause sodium retention, and excessive sodium intake can lead to fluid retention and increased blood pressure.
• Maintain a balanced diet rich in fruits, vegetables, and whole grains to support overall well-being during Moclobemide therapy.
• Stay well-hydrated by drinking adequate water to support the body's metabolism and overall health while taking Moclobemide.

Moclobemide 150MG Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area. Keep the tablets in their original packaging, ensuring the container is tightly sealed to maintain their integrity. It is crucial to avoid exposure to sunlight, moisture, or extreme temperatures, as these can degrade the medication. Do not store the tablets in the bathroom or kitchen, as humidity and heat can impact their effectiveness. Always check the expiration date, and if the tablets are past their expiry, dispose of them properly, but do not flush them down the toilet or throw them into the trash. Consult your pharmacist or local waste management guidelines for appropriate disposal methods to ensure environmental safety. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Moclobemide 150MG Tablet:

• Take the tablet as directed by your doctor, typically once daily in the morning.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Avoid consuming alcohol while taking this medication.
• Do not stop taking the medication suddenly, gradually taper off as advised by your doctor.
• Inform your doctor about all medications you are currently taking to avoid potential interactions.
• Store the tablets in a cool, dry place, away from direct sunlight.
• If you experience any unusual thoughts or behaviors, contact your doctor immediately.