Avelox (400mg/250ml) Infusion

Avelox (400mg/250ml) Infusion

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  • Manufacturer Bayer Pakistan (Pvt.) Ltd.
  • Generic Name Moxifloxacin

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Storage/Disposal
  • Description

    Moxifloxacin is a powerful antibiotic used to treat a wide range of bacterial infections. It operates by inhibiting the action of the bacterial enzyme DNA gyrase, which is essential for bacterial DNA replication, transcription, and repair. By binding to the ATP-binding pocket of DNA gyrase, Moxifloxacin prevents the enzyme from undergoing the necessary conversion that allows it to facilitate topoisomerase II activity. This inhibition leads to the accumulation of single-strand breaks in the bacterial DNA, causing cell death.Against gram-positive bacteria such as Staphylococcus aureus and Streptococcus pneumoniae, as well as against gram-negative bacteria such as Escherichia coli and Klebsiella pneumoniae, Moxifloxacin demonstrates particular effectiveness. Due to its higher affinity for its target enzyme compared to other fluoroquinolones, it can achieve higher concentrations at the site of infection, making it more effective. Moxifloxacin's mechanism of action makes it an invaluable tool in the treatment of bacterial infections, particularly those resistant to other antibiotics. However, to minimize the risk of antibiotic resistance and adverse effects, it is vital to use this medication prudently.

  • Ingredients

    Moxifloxacin
  • Drug Class

    Quinolones

  • Dosage Form

    injection
  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Treat a wide variety of bacterial infections of the sinuses, skin, pneumonia, bones, joints, lungs, blood, and heart.
    • Strep throat and tonsillitis
    • Skin and skin structure infections, including methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA)
    • Community-acquired pneumonia (CAP)
    • Hospital-acquired pneumonia (HAP), including ventilator-associated pneumonia (VAP)
    • Acute bacterial skin and skin structure infections (ABSSSI)
    • UTI, including those caused by MRSA
    • Cervical adenitis (swollen lymph nodes) caused by Staphylococcus aureus or Streptococcus species
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • The recommended dosage for adults and adolescents (12 years and older) is 400mg taken once daily for 7-14 days, with or without food. Doses up to 600mg once daily may be used for more severe cases of infection under a doctor's guidance.
    • It is essential to take the medication as directed and complete the course of treatment even if symptoms improve to prevent antibiotic resistance and ensure complete resolution of the infection.
    • The dosage may be reduced or adjusted for those with kidney problems to avoid potential complications.
    • You must contact your doctor or pharmacist before taking Moxifloxacin to ensure you receive the correct dosage and advice on taking the medication.
    • Most people do not experience side effects when taking Moxifloxacin at the correct dosage. However, if you experience any side effects, please contact your medical professional immediately.
  • In case of Overdose

    An overdose of moxifloxacin is a serious matter that requires immediate medical attention. If you suspect someone has experienced an overdose of this antibiotic, it is crucial to contact your local emergency services or Poison Control right away. The emergency responders are well-equipped to provide you with guidance on handling the situation, which may include inducing vomiting or performing a gastric lavage to empty the stomach of any remaining medication. They may also recommend the use of activated charcoal to reduce the absorption of the overdose.

  • Missed Dose

    When missing a dose of moxifloxacin 400mg, it is crucial to take it as soon as possible. However, if it is already near the time for your next dose, it is recommended to skip the missed dose and proceed with your regular dosage schedule. Doubling up on doses is not advised. For further guidance on missing a dose, contact your healthcare provider or pharmacist. It is important to adhere to the instructions of your healthcare provider when taking any medication. Depending on a patient's medical history and the laws of the country where the medication is consumed, different instructions may apply. It is best to consult with a trusted medical professional for precise and comprehensive advice on the medication and its effects. Sources used for this answer include:

  • How To Use

    Before you begin using Moxifloxacin 400mg, it is important to read the medication guide provided by your pharmacist. This guide will provide you will all the information you need to use the medication safely and effectively. If you have any questions, be sure to ask your doctor or pharmacist. To take Moxifloxacin, you will typically take it by mouth once daily, with or without food. However, the timing and dosage amount will depend on your medical condition and your doctor's recommendations. It is important to follow your doctor's instructions carefully and not deviate from the schedule they set for you. Since Moxifloxacin can potentially cause some side effects, it is important to stay aware of any adverse reactions you may experience. Some common side effects include nausea, diarrhea, and sensitivity to sunlight. It is also important to avoid alcohol during treatment, as well as antacids that contain aluminum or magnesium for at least two hours before and after taking Moxifloxacin. Let your doctor know if you are taking any other medications, particularly any other antibiotics or if you have recently taken any antacids. This will allow your doctor to provide you with the safest and most effective use of Moxifloxacin. If you are using this medication to treat traveler's diarrhea, it is important to finish the full course of treatment, even if your symptoms improve quickly. Stopping the medication too early could result in a relapse of the infection. If you experience any severe side effects or anything that concerns you during your treatment, be sure to consult with your doctor or pharmacist right away.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • Are allergic to Moxifloxacin, Escherichia coli, or any of the other ingredients in the tablet.
    • Have any type of flu, influenza, virus, or infection as this medicine is specifically for treating bacterial infections. Taking it might worsen any viral infections you have.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Increased sensitivity to sunlight, may include sunburn, skin rash, itching, peeling
    • Blurred vision
    • Burning, itching, or watery eyes
    • Dry or gritty eyes
    • Feeling dizzy
    • Temperature sensation disturbances
    • Reduced appetite
  • Storage/Disposal

    Moxifloxacin is a prescription antibiotic that comes in 400mg tablets and should be stored at room temperature at about 20 degrees Celsius. It should be kept in a cool, dry place, away from heat and light. Ensure to keep the container closed and storage instructions on the medication label followed as they provide accurate instructions for that particular drug. It is also important to keep moxifloxacin out of reach of children, pets, and unauthorized individuals. Specific storage instructions on the label of the medication should be carefully adhered to as a deviation from these instructions can lead to medication degradation and loss of efficacy. In case of doubt, it is recommended to always consult a healthcare professional for guidance specific to the medication and your medical condition.

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