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Pheniramine maleate, an active ingredient in tablets, is an antihistamine that primarily exerts its effects by antagonizing histamine H1 receptors. This mechanism of action is crucial in blocking the actions of histamine, a chemical released during allergic reactions. By binding to the H1 receptors, pheniramine maleate inhibits the activation of these receptors, thereby reducing the symptoms associated with allergies. This action helps to alleviate conditions such as itching, sneezing, and hives by suppressing the histamine-induced responses in the body, providing relief to individuals suffering from allergic reactions.

Antihistamine

Tablet

The following are the uses of Pheniramine Maleate Tablet:

• Used for temporary relief of sneezing, runny nose, and itching due to hay fever or other upper respiratory allergies.
• Used for reducing symptoms of the common cold, such as itchy and watery eyes, and sinus congestion.
• Used for treating allergic skin conditions like hives and itching.
• Used for alleviating motion sickness symptoms, including nausea and vomiting.
• Used for providing relief from mild, allergic skin reactions and insect bites.
• Used for managing certain types of allergic reactions, helping to reduce inflammation and discomfort.
• Used for short-term control of severe allergic reactions as part of emergency treatment.

In the case of an overdose of Pheniramine Maleate Tablets, individuals may experience symptoms such as drowsiness, dizziness, dry mouth, and difficulty in concentration. In more severe cases, it can lead to rapid heartbeat, confusion, and even hallucinations. Promptly seek medical assistance if an overdose is suspected, as healthcare professionals can provide appropriate treatment and support to manage the symptoms effectively and ensure the patient's well-being.

In the case of a missed dose of Pheniramine Maleate Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication. It is advisable to set reminders or use a pill organizer to help you remember to take your medication as prescribed.

To take Pheniramine Maleate Tablets, place the tablet on your tongue and allow it to dissolve completely, without chewing or crushing, and then swallow with water; take the tablet as directed by your healthcare provider, typically once every 4 to 6 hours, but follow the specific instructions provided for your condition.

Here are the conditions and situations when Pheniramine Maleate Tablet should not be taken:

• Avoid using if you have a known allergy or hypersensitivity to Pheniramine Maleate or any of the excipients in the tablet.
• Not suitable for individuals with narrow-angle glaucoma.
• Should not be used in patients with severe liver or kidney impairment.
• Contraindicated in patients with a history of asthma, bronchitis, or other respiratory issues.
• Avoid using this medication if you have a blockage in your stomach or intestines.
• Not recommended for individuals with an enlarged prostate or urinary retention problems.
• Do not use in newborns or premature infants.
• Should not be given to patients with a history of seizures or epilepsy.
• Avoid using this medication if you have an overactive thyroid (hyperthyroidism).
• Not suitable for individuals with a history of cardiovascular diseases or hypertension.
• Do not administer to patients with severe coronary artery disease.
• Contraindicated in patients who have taken monoamine oxidase inhibitors (MAOIs) in the last 14 days.
• Should not be used in individuals with a history of gastrointestinal obstruction.
• Avoid using this medication if you have a blood disorder or low blood pressure.
• Not recommended during breastfeeding.

The side effects of Pheniramine Maleate Tablet may include:

• Drowsiness or sedation
• Dry mouth
• Blurred vision or dizziness
• Nausea and vomiting
• Constipation or diarrhea
• Difficulty in urination
• Confusion or disorientation, especially in elderly individuals
• Increased sensitivity to sunlight

Following are the precautions and warnings for Pheniramine Maleate Tablet:

• This medication should not be used in individuals with a known hypersensitivity or allergy to Pheniramine Maleate or any other antihistamines.
• It may cause drowsiness and impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you.
• Alcohol consumption should be avoided as it can increase the risk of side effects.
• Patients with a history of asthma, glaucoma, or bladder/urinary problems should use this medication with caution and under medical supervision.
• Pheniramine Maleate may interact with other medications; inform your doctor about all the medicines you are currently taking.
• Not recommended for use in pregnant or breastfeeding women without medical advice, as it may pose risks to the fetus or infant.
• Keep this medication out of reach of children and pets.

Following are the drug interactions for Pheniramine Maleate Tablet:

• Alcohol and other central nervous system (CNS) depressants, such as benzodiazepines or opioids, may increase the sedative effects, leading to excessive drowsiness and impaired motor skills.
• Monoamine oxidase inhibitors (MAOIs) can interact, causing a potentially fatal condition known as serotonin syndrome. Avoid concurrent use.
• Tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs) can enhance the anticholinergic effects, leading to confusion, dry mouth, and blurred vision.
• Antihistamines and antipsychotics may increase the risk of QT prolongation, a heart rhythm disorder. Close monitoring is required.
• Drugs that lower the seizure threshold, such as certain antidepressants and antipsychotics, may increase the risk of seizures when combined with Pheniramine.
• Antacids containing aluminum or magnesium can decrease the absorption of Pheniramine, reducing its effectiveness.
• Pheniramine may increase the effects of anticholinergic drugs, causing urinary retention and constipation.

Following are the food interactions to be aware of when taking Pheniramine Maleate Tablets:

• Avoid consuming alcohol during the medication period, as it may increase the drowsiness and dizziness associated with the drug's side effects.
• Citrus fruits like grapefruits and their juices should be avoided as they can interfere with the drug's metabolism, potentially leading to increased side effects.
• Caffeine intake should be monitored as it may exacerbate nervousness and restlessness, which are potential side effects of the medication.
• Foods high in sugar and fat may be discouraged, especially if the medication is being used for weight control, as they can counteract the drug's intended effects.
• Spicy foods might be best avoided as they could potentially irritate the stomach, especially if the medication is taken on an empty stomach.
• Stay well-hydrated by drinking plenty of water to help prevent dehydration, particularly if you experience dry mouth as a side effect.
• There are no specific food restrictions with Pheniramine Maleate, but a balanced diet is always recommended to support overall health.

Pheniramine Maleate Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The medication container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to expose the tablets to extreme temperatures or store them in bathrooms or near heat sources, as this can compromise their effectiveness. Proper disposal of unused or expired tablets is essential; do not flush them down the toilet or pour them into drainage systems. Consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep the medication away from children to prevent accidental consumption.

Following are the quick tips for Pheniramine Maleate Tablet:

• Consult a doctor or pharmacist for the correct dosage, especially for children.
• Swallow the tablet whole without crushing or chewing for optimal absorption.
• Take with a full glass of water for easy swallowing.
• Avoid taking with alcohol as it may increase drowsiness.
• Do not drive or operate machinery if the tablet causes drowsiness.
• Inform your doctor about all medications you are taking to avoid potential interactions.
• Store in a cool, dry place, away from direct sunlight and moisture.