Axicobal (500mcg) 100 Tablets

Mecobalamin, also known as vitamin B12, is a synthetic form of vitamin B12 commonly used to treat vitamin B12 deficiency and alleviate symptoms of certain neurological disorders. This vitamin is essential for human metabolism and plays a critical role in the production of red blood cells, DNA synthesis, and nerve function. When consumed, mecobalamin is converted into its coenzyme forms, methylcobalamin and adenosylcobalamin, which are the active forms of vitamin B12 that provide therapeutic benefits. In the small intestine, vitamin B12 binds to a glycoprotein called intrinsic factor, which enables its absorption through the ileum and promotes its efficient transport to the liver for storage. The liver then releases vitamin B12 when required, transporting it to different tissues throughout the body. This water-soluble vitamin is involved in various biochemical processes, including the metabolism of nucleic acids, amino acids, and lipids.

Mecobalamin

Vitamin B12 (Cyanocobalamin And Analogues)

Tablet

Mecobalamin is utilized for the following therapeutic indications:

• Treatment of peripheral neuropathy
• Management of diabetic neuropathy
• Support in the treatment of anemia caused by vitamin B12 deficiency
• Helps improve nerve function and regeneration
• May assist in the recovery of nerve damage in certain neurological conditions
• Used in the management of methylmalonic acidemia
• Promotes overall nerve health and functioning

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For neuropathy due to myelopathy, nerve injury, or vitamin B12 deficiency- 1250 µg (1 tab or capsule, 500 mg intravenously) once daily for 7-10 days followed by monthly injections of 1000 µg for life.
• For nutritional supplementation in cases of malabsorption (e.g. ileal resection, gastrectomy)- 500 µg daily.
• For dialysis patients- Continuous infusion of 1000 µg per day or pulsed doses of 2000 µg 3 times a week.
• For prevention of pathology from creeping dementia or depression- 1000 µg daily.
• For asthma- 1000 µg daily for 3 months.

An overdose of methylcobalamin, a vitamin B12 supplement, may cause megaloblastic anemia, sensory neuropathy, and auditory disturbances. These symptoms are reversible with medical intervention and vitamin B12 supplementation within a short period. If you have had an overdose or had an adverse reaction to methylcobalamin, it is important to seek medical attention immediately. Patients with an overdose should be closely monitored for megaloblastic anemia and neuropathy. This monitoring should include frequent laboratory assessments and neurologic examinations. Medical professionals may consider gastric lavage if ingestion was recent. Treatment of methylcobalamin overdose is primarily supportive, and symptom-driven. If you feel you have overdosed, or have had an adverse reaction to mecobalamin, it is important to seek out medical attention immediately.

Maintaining a consistent schedule for taking supplements is crucial, especially when it comes to mecobalamin 500mg. If you happen to miss a dose, it's recommended to take it as soon as possible. However, if you're close to your next scheduled dose, it's better to skip the missed dose and continue with your regular schedule. It's important to avoid doubling up on doses or taking extra doses without consulting a doctor, as this can lead to an overdose or side effects. For optimal and desired outcomes, maintain a regular timing and stick to your schedule as much as possible to avoid missing doses.

Before taking MECOBALAMIN 500, it is important to understand its proper usage and precautions to ensure safety and effectiveness. First, it is important to adhere to the recommended dosage of 500 to 2,000 mcg per day, as advised by your medical practitioner or the product label. Adjusting the dosage on your own can lead to harmful effects and possibly negate the benefits of the supplement. Next, it is recommended that MECOBALAMIN 500 be taken at mealtimes, as doing so facilitates better absorption. You can take it with or without food, according to your preference, but it is best to maintain a consistent schedule and take it at the same time each day. The duration of use depends on individual needs and is influenced by the patient's medical condition and response to treatment. It is typically used on an ongoing basis to maintain adequate levels of vitamin B12 in the body. MECOBALAMIN 500 does not known to have any harmful interactions with food or other medications. However, it is always better to be safe than sorry, and it is highly recommended to inform your doctor about all the medications or supplements you are taking, including over-the-counter products. In terms of precautions, it is important to notify your doctor if you have any known allergies to MECOBALAMIN 500 or any of its ingredients. Women who are pregnant or breastfeeding should only use this medication if it is deemed necessary and under medical supervision. Additionally, if you have any conditions or take any medications that affect your kidneys, stomach, or have a blood disorder, it is advised to consult with your doctor before use. Lastly, heavy alcohol consumption should be avoided as it may impede the effectiveness of the medication. Overall, to safely and effectively use MECOBALAMIN 500, it is important to follow the guidelines provided by your doctor or the product label, and always consult with your medical practitioner if you

Discerning instances where this medication may not be appropriate:

• It is vital to consult with a doctor before taking Mecobalamin if you have any allergies, are taking any other medications, or have kidney dysfunction.
• You should not take this medication if you have Leber's disease, any skin infection or allergy to injections, or if you are pregnant or concerned about safe intake during pregnancy.
• Stop taking the medication if you have an allergic reaction such as difficulty breathing, rash, or swelling of the throat or lips after taking Mecobalamin, and seek medical attention immediately.

Unraveling the side effects lurking behind this medications are as follows:

• Headache
• Nausea
• Diarrhea
• Blurred vision
• Itchiness
• Anxiety
• Irritability
• Fast heart rate

Store methylcobalamin or mecobalamin 500mg in a cool, dry place, preferably away from direct heat or light. Choose a cupboard or drawer in a room that has a stable temperature in your home. Avoid storing it in the bathroom or kitchen, where temperatures and humidity may be higher due to proximity to water sources or heat sources such as stoves.Keep the methylcobalamin or mecobalamin 500mg out of the reach of children and pets to avoid accidental consumption. Do not store it in damp places, near sinks or stoves, or anywhere else that moisture levels may be high, to avoid mould forming on the container or the pill itself. Protect the methylcobalamin or mecobalamin 500mg from freezing temperatures, which can alter the medication's composition and render it ineffective. Freezing temperatures can compromise the integrity of the supplement.Do not leave the methylcobalamin or mecobalamin 500mg in your car, as extreme temperatures can occur there too. A car is subjected to varying extremes of hot and cold temperatures, which can harm the supplement. Remember to keep the methylcobalamin or mecobalamin 500mg in its original container or packaging. Do not transfer it to another container, as that can interfere with proper storage conditions and expose the supplement to variables that may diminish its effectiveness or compromise its safety. If the methylcobalamin or mecobalamin 500mg comes in a vial, it should be stored in the vial until ready for use. If you have any specific questions or concerns about storing methylcobalamin or mecobalamin 500mg, consult your physician