AZILAZON 40MG TAB 30S.

Azilsartan medoxomil is a prodrug that belongs to the angiotensin II receptor blocker (ARB) class of medications. It works by blocking the action of angiotensin II, a potent vasoconstrictor hormone, on its receptors in the body. Specifically, azilsartan medoxomil is metabolized in the body to azilsartan, which selectively binds to and blocks the angiotensin II type 1 (AT1) receptors. By blocking these receptors, azilsartan medoxomil prevents the binding of angiotensin II, leading to vasodilation, decreased blood pressure, and reduced strain on the heart. This mechanism of action helps to lower blood pressure, improve blood flow, and reduce the risk of cardiovascular events in patients with hypertension or other cardiovascular conditions.

Angiotensin II Receptor Blocker

Tablet

The following are the uses of Azilsartan Medoxomil 40MG Tablet:

• Used for treating high blood pressure (hypertension).
• Used to lower blood pressure and reduce the risk of stroke, heart attack, and kidney problems.
• Used in patients with hypertension to improve cardiovascular health.
• Used to control blood pressure and prevent related complications.
• Used as part of a treatment plan to manage hypertension effectively.
• Used to provide 24-hour blood pressure control.
• Used in cases where blood pressure management is crucial for overall health.

In the case of an overdose of Azilsartan Medoxomil 40MG Tablet, it is important to recognize the signs and symptoms, which may include severe dizziness, fainting, or an irregular heartbeat. If an overdose is suspected, it is crucial to seek medical assistance promptly. The healthcare provider may recommend inducing vomiting or administering activated charcoal to prevent further absorption of the medication. Prompt action can help mitigate the potential risks associated with an overdose.

In the case of a missed dose of Azilsartan Medoxomil 40MG Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one. If you frequently miss doses, consider setting reminders or asking someone to remind you to take your medication at the same time each day to maintain consistency.

To take Azilsartan Medoxomil 40MG Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, without crushing or chewing the tablet.

Azilsartan Medoxomil 40MG Tablet should not be used in the following conditions or situations:

• Must not be taken by individuals with a known allergy or hypersensitivity to Azilsartan Medoxomil or any other angiotensin II receptor blockers (ARBs).
• Not suitable for individuals with severe liver disease or impaired liver function.
• Contraindicated in pregnant women, especially during the second and third trimesters, as it can cause harm to the fetus.
• Should not be used in breastfeeding women, as it may pass into breast milk and harm the nursing infant.
• Not recommended for individuals with severe kidney disease or those on dialysis, as dosage adjustments may not be sufficient.
• Avoid using this medication in children and adolescents, as its safety and efficacy have not been established in this age group.
• Do not use if you have a condition called hyperaldosteronism, where the adrenal glands produce too much of a certain hormone.

The side effects of Azilsartan Medoxomil 40MG Tablet may include:

• Dizziness
• Fatigue or weakness
• Nausea and vomiting
• Diarrhea
• High potassium levels (hyperkalemia)
• Joint pain
• Low blood pressure (hypotension)
• Increased urination

Following are the precautions and warnings for Azilsartan Medoxomil 40MG Tablet:

• This medication is not recommended for individuals with a known allergy to Azilsartan or any other angiotensin receptor blockers (ARBs).
• Patients with a history of liver or kidney disease should exercise caution, as the dosage may need adjustment under medical supervision.
• It may cause dizziness or lightheadedness, so caution is advised when performing tasks that require alertness, such as driving or operating machinery.
• Elderly patients may be more sensitive to the effects of this medication, and regular monitoring is recommended.
• Pregnant or breastfeeding women should consult their doctor before taking this medication, as it may have potential risks to the fetus or infant.
• If you have a history of angioedema or are undergoing surgery, inform your doctor, as Azilsartan may need to be temporarily discontinued.
• Patients with severe vomiting, diarrhea, or excessive sweating should be monitored closely, as it can lead to dehydration and potential kidney problems.
• Regular blood pressure monitoring is essential while taking this medication to ensure it is effectively controlling your blood pressure.

Following are the drug interactions for Azilsartan Medoxomil 40MG Tablet:

• Azilsartan may increase the levels of lithium, leading to potential toxicity. Close monitoring of lithium levels is necessary.
• The use of Azilsartan with diuretics, especially potassium-sparing diuretics, can cause elevated potassium levels in the blood.
• When combined with NSAIDs (non-steroidal anti-inflammatory drugs), Azilsartan may lead to reduced antihypertensive effects and potential kidney damage.
• Angiotensin receptor blockers like Azilsartan can decrease the elimination of digoxin, increasing its levels in the body.
• The use of Azilsartan with other antihypertensives, such as beta-blockers or ACE inhibitors, can result in additive effects and potentially excessive blood pressure reduction.
• Combining Azilsartan with potassium supplements may cause hyperkalemia, especially in patients with renal impairment.
• Azilsartan may enhance the effects of anti-diabetic medications, potentially leading to hypoglycemia.

Following are the food interactions for Azilsartan Medoxomil 40MG Tablet:

• Avoid excessive salt (sodium) intake as it can reduce the effectiveness of Azilsartan in controlling blood pressure. High-sodium foods like processed snacks, canned soups, and fast food should be limited.
• Potassium-rich foods like bananas, oranges, and spinach should be consumed moderately as Azilsartan may increase potassium levels. Monitoring is crucial to prevent hyperkalemia.
• Maintain a balanced diet with controlled portions of carbohydrates, proteins, and healthy fats. This supports overall cardiovascular health and aids in blood pressure management.
• Limit alcohol consumption as it may interact with Azilsartan, potentially increasing side effects and impacting blood pressure control. Moderation is key.
• Grapefruit and grapefruit juice should be avoided as they can interfere with the metabolism of Azilsartan, leading to increased drug levels and potential side effects.
• Staying well-hydrated is essential, but avoid excessive fluid intake as it may affect blood pressure and interact with the medication's diuretic effects.
• Consult a dietician for a personalized meal plan, especially if you have comorbidities like diabetes or kidney issues, to ensure a diet compatible with Azilsartan therapy.

Azilsartan Medoxomil 40MG Tablets should be stored in a secure and dry location, preferably in a medicine cabinet, at room temperature (around 25°C/77°F). Ensure the tablets are kept in their original container, tightly sealed, to maintain their integrity and protect them from moisture and light. It is crucial not to store them in the bathroom or kitchen, as these areas may expose the medication to heat and humidity, potentially affecting its potency. When disposing of unused or expired tablets, do not throw them into the trash or flush them down the toilet. Instead, follow local guidelines for pharmaceutical waste disposal or consult your pharmacist for safe and environmentally friendly disposal options. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Azilsartan Medoxomil 40MG Tablet:

• Consult your doctor before starting this medication, especially if you have kidney or liver problems.
• Take the tablet as directed by your doctor, usually once daily.
• It can be taken with or without food, but consistency is key.
• Swallow the tablet whole; do not crush or chew it.
• Maintain a consistent medication schedule to ensure effectiveness.
• Avoid taking potassium supplements or potassium-rich foods without medical advice.
• Regular blood pressure monitoring is recommended while on this medication.
• Inform your doctor about all medications you're taking to prevent potential interactions.