AZILAZON 80MG TAB 30S.

Azilsartan medoxomil is a prodrug that belongs to the angiotensin II receptor blocker (ARB) class of medications. Its mechanism of action is centered on blocking the angiotensin II receptors, specifically the AT1 receptors. When azilsartan medoxomil is absorbed into the body, it is rapidly converted to its active form, azilsartan. Azilsartan competitively binds to AT1 receptors, preventing the binding of angiotensin II, a potent vasoconstrictor hormone. By blocking the effects of angiotensin II, azilsartan medoxomil leads to vasodilation, reduced blood pressure, and decreased vascular resistance. This mechanism helps in the management of hypertension by promoting relaxation of blood vessels, which in turn improves blood flow and lowers blood pressure without affecting heart rate.

Angiotensin II Receptor Blocker

Tablet

The following are the uses of Azilsartan Medoxomil 80MG Tablet:

• Used for treating high blood pressure (hypertension)
• Used to lower and control blood pressure, reducing the risk of strokes, heart attacks, and kidney problems
• Used to improve blood flow and decrease the workload on the heart
• Used for managing hypertension in patients who have difficulty controlling their blood pressure with other medications
• Used as an effective treatment option for those with stage 2 hypertension
• Used to help relax and widen blood vessels, allowing blood to flow more easily
• Used to improve overall cardiovascular health and prevent long-term complications
• Used under medical supervision, with regular monitoring of kidney function and blood pressure

In the case of an overdose of Azilsartan Medoxomil 80MG Tablet, it is important to recognize the potential severity of the situation. Symptoms may include a significant drop in blood pressure, leading to dizziness, fainting, or even shock. Prompt medical intervention is necessary to manage these symptoms and prevent further complications. Emergency medical services should be contacted immediately to ensure proper treatment and monitoring. Timely action can help mitigate the risks associated with an overdose.

In the case of a missed dose of Azilsartan Medoxomil 80MG Tablet, it is important to take the medication as soon as you remember. However, if it is close to the time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen. It is recommended to set reminders or use pill organizers to help you stay on track with your medication routine.

To take Azilsartan Medoxomil 80MG Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.

Here are the conditions or situations when Azilsartan Medoxomil 80MG Tablet should not be taken:

• Avoid if you have a known allergy or hypersensitivity to Azilsartan Medoxomil or any other angiotensin II receptor blockers (ARBs).
• Not recommended for individuals with severe liver impairment or biliary obstruction.
• Contraindicated in pregnant women, especially during the second and third trimesters, as it can cause harm to the fetus.
• Should not be used in breastfeeding women, as it may pass into breast milk and harm the nursing infant.
• Do not take if you have a history of angioedema, a serious allergic reaction, after taking Azilsartan or other ARBs.
• Not suitable for individuals with severe renal impairment or patients on dialysis.
• Avoid in children and adolescents, as the safety and efficacy in this age group have not been established.
• Do not use if you have low blood pressure (hypotension), as it can further lower blood pressure.
• Should not be used as the sole treatment for severe or symptomatic heart failure.

The side effects of Azilsartan Medoxomil 80MG Tablet may include:

• Dizziness or lightheadedness
• Fatigue or weakness
• Nausea and vomiting
• Diarrhea or constipation
• Muscle cramps or joint pain
• Increased potassium levels in the blood (hyperkalemia)
• Elevated blood urea nitrogen (BUN) and creatinine levels
• Cold-like symptoms (upper respiratory tract infection)

Following are the precautions and warnings for Azilsartan Medoxomil 80MG Tablet:

• This medication is not recommended for individuals with a known allergy or hypersensitivity to Azilsartan Medoxomil or any other angiotensin II receptor blockers.
• Patients with a history of severe liver disease should exercise caution and have their liver function monitored regularly while on this medication.
• Azilsartan Medoxomil can cause dizziness and lightheadedness, especially when standing up from a sitting or lying position. Elderly patients should be cautious to avoid falls.
• It may cause hyperkalemia (high potassium levels in the blood), so regular monitoring of potassium levels is necessary, especially in patients with kidney disease.
• Patients with a history of low blood pressure should be cautious as this medication can further lower blood pressure, especially during the initial phase of treatment.
• This drug may not be suitable for pregnant or breastfeeding women, as it could potentially cause harm to the fetus or infant. Alternative treatments should be considered.
• Patients undergoing surgery, including dental procedures, should inform their healthcare provider about Azilsartan Medoxomil use to prevent complications.

Following are the drug interactions for Azilsartan Medoxomil 80MG Tablet:

• It may increase the risk of hyperkalemia when used with potassium-sparing diuretics, potassium supplements, or salt substitutes containing potassium.
• Azilsartan may cause excessive blood pressure drop when used with other antihypertensive medications, such as beta-blockers or diuretics.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce the blood pressure-lowering effect of Azilsartan.
• Azilsartan can enhance the effects of antidiabetic medications, potentially leading to hypoglycemia.
• When combined with certain immunosuppressants, it may increase the risk of infections.
• The effectiveness of Azilsartan may be reduced by non-steroidal anti-inflammatory drugs and high-dose aspirin.
• Caution is advised when using Azilsartan with angiotensin-converting enzyme (ACE) inhibitors, as it may lead to impaired kidney function.

Following are the food interactions for Azilsartan Medoxomil 80MG Tablet:

• Grapefruit and grapefruit juice should be consumed with caution as they can increase the blood levels of Azilsartan, potentially causing an excessive drop in blood pressure.
• Alcohol may increase the risk of side effects like dizziness and lightheadedness, especially when taken in large quantities. It is advisable to limit alcohol consumption while on this medication.
• High-salt foods should be avoided as Azilsartan is a blood pressure medication, and excessive salt intake can reduce its effectiveness and counteract its blood pressure-lowering effects.
• Foods rich in potassium, like bananas and oranges, should be consumed in moderation as Azilsartan can increase potassium levels in the blood, and excessive potassium intake may lead to irregular heart rhythms.
• Maintain a balanced diet and avoid excessive consumption of fatty foods, as they may interact with the medication's absorption and distribution in the body.
• Avoid herbal supplements, especially those affecting blood pressure, without consulting your doctor, as they may interact with Azilsartan.
• Stay hydrated by drinking plenty of fluids, but avoid excessive fluid intake, which could affect your blood pressure.
• Consult your healthcare provider for personalized dietary recommendations while taking Azilsartan Medoxomil.

Azilsartan Medoxomil 80MG Tablets should be stored in a secure and dry location, preferably in a medicine cabinet, at room temperature, maintaining a consistent temperature between 68°F and 77°F (20°C and 25°C). Protect the tablets from light exposure by keeping them in their original container, ensuring the bottle is tightly sealed. It is crucial to keep this medication out of the reach of children and pets to prevent accidental ingestion. When disposing of unused or expired tablets, do not flush them down the toilet or throw them into the trash. Instead, consult your pharmacist or local waste disposal company for safe and environmentally friendly disposal options to prevent potential harm to the environment.

Following are the quick tips for Azilsartan Medoxomil 80MG Tablet:

• Consult your doctor before starting this medication to ensure it's suitable for you.
• Take the tablet as directed by your healthcare provider, typically once daily.
• Consume the tablet whole with a full glass of water, preferably at the same time each day.
• Avoid crushing, chewing, or breaking the tablet, as it should be swallowed intact.
• Maintain a consistent medication schedule for optimal blood pressure control.
• Inform your doctor about all the medications you're taking to prevent potential interactions.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.