Bactinor (0.3%) 5ml Eye Drops

Norfloxacin, a broad-spectrum fluoroquinolone antibiotic, exerts its bactericidal effect by targeting bacterial DNA gyrase and topoisomerase IV enzymes, essential for DNA replication and cell division. This interference leads to the inhibition of bacterial DNA synthesis, resulting in bacterial cell death. Norfloxacin is particularly effective against a wide range of Gram-negative and some Gram-positive bacteria, including those responsible for various eye infections. The drug's mechanism of action ensures that it disrupts the bacterial cell's ability to replicate and survive, making it a potent treatment option for ocular infections caused by susceptible microorganisms.

Fluoroquinolone antibiotic.

Drop

The following are the uses of Norfloxacin Drop:

• Used for treating bacterial infections in the eyes
• Used for eye infections like conjunctivitis and corneal ulcers
• Used for reducing inflammation and pain caused by bacterial eye issues
• Used as an alternative to eye ointments for easier application
• Used to prevent the spread of bacterial eye infections
• Used for maintaining eye health during recovery
• Used to ensure effective treatment of eye conditions caused by bacteria

In the case of an overdose of Norfloxacin Drops, it is important to recognize the potential symptoms, which may include nausea, vomiting, and dizziness. If you suspect an overdose, seek medical advice promptly. The healthcare provider may recommend monitoring and supportive care to manage the symptoms. It is advisable to keep this medication out of reach of children to prevent accidental ingestion. Always follow the prescribed dosage to minimize the risk of overdose.

In the case of a missed dose of Norfloxacin eye drops, it is important to administer the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for the missed one. If you miss multiple doses, contact your healthcare professional for advice on how to proceed, as they may recommend adjusting your dosage schedule accordingly.

To use Norfloxacin eye drops, gently tilt your head back, pull the lower eyelid down to create a pocket, and instill the prescribed number of drops into the eye without touching the dropper to any surface, including the eye or face, then close your eyes gently to facilitate even distribution of the medication.

Following are the conditions/situations when Norfloxacin Drops should not be used:

• Avoid using Norfloxacin Drops if you have a known allergy or hypersensitivity to any quinolone antibiotics.
• Do not use the drops if you have a history of tendon disorders or tendon rupture, especially after using fluoroquinolone antibiotics.
• Contraindicated in individuals with a personal or family history of an abnormal heart rhythm, especially QT prolongation.
• Not suitable for children and adolescents below 18 years of age, as it may affect bone and joint development.
• Avoid using the drops if you have severe central nervous system (CNS) disorders, such as epilepsy or seizures.
• Should not be used in patients with myasthenia gravis as it can worsen muscle weakness.
• Contraindicated in individuals with a deficiency of a specific enzyme called glucose-6-phosphate dehydrogenase (G6PD).
• Do not use Norfloxacin Drops if you have a history of psychiatric disorders, as it may trigger or worsen symptoms.

The side effects of Norfloxacin Drop may include:

• Increased sensitivity to light (photosensitivity)
• Dizziness
• Headache
• Nausea and vomiting
• Diarrhea or loose stools
• Skin rash or itching
• Vaginal itching or discharge
• Fatigue

Following are the precautions and warnings for Norfloxacin Eye Drops:

• Norfloxacin eye drops are for external use only and should not be ingested. Avoid contact with the mouth or nose.
• Wash your hands before and after applying the eye drops to prevent contamination.
• Do not wear contact lenses while using these drops unless advised by your doctor.
• Inform your doctor if you have a history of epilepsy or seizures, as these drops may trigger seizures in susceptible individuals.
• Discontinue use and seek medical attention if you experience any allergic reactions, severe eye irritation, or vision changes.
• Do not use the drops if the solution becomes discolored or cloudy, as this may indicate contamination.
• Keep out of reach of children and pets. Store in a cool, dry place away from direct sunlight.

Following are the drug interactions for Norfloxacin Drops:

• Avoid using with other quinolone antibiotics, as it may increase the risk of adverse effects.
• Norfloxacin can reduce the effectiveness of oral typhoid vaccine and live cholera vaccine.
• May interact with antacids containing magnesium or aluminum, reducing Norfloxacin absorption.
• Probenecid and NSAIDs may increase Norfloxacin levels in the body, leading to potential toxicity.
• Theophylline levels can be increased when used with Norfloxacin, requiring monitoring.
• Warfarin and other anticoagulants may have enhanced effects, requiring close monitoring.
• The risk of central nervous system side effects may increase when combined with certain medications like antipsychotics or antidepressants.

Following are the food interactions for Norfloxacin Drops:

• Avoid consuming dairy products like milk, yogurt, or cheese, as they can decrease the absorption of Norfloxacin, reducing its effectiveness.
• Caffeine intake should be minimized as it may enhance the side effects of Norfloxacin, especially nervous system stimulation.
• Avoid alcohol consumption as it can increase the risk of central nervous system side effects and may also impair your thinking or reactions.
• Grapefruit and grapefruit juice should be avoided as they can increase the levels of Norfloxacin in the blood, potentially leading to increased side effects.
• Iron-rich foods like red meat, spinach, and iron supplements should be taken separately from Norfloxacin, as iron can decrease the absorption of the medication.
• Maintain a consistent intake of water and stay well-hydrated during the course of treatment.
• Consume a balanced diet to support overall health and potentially reduce the severity of side effects.
• Consult your healthcare provider for personalized advice regarding dietary restrictions and interactions.

Norfloxacin eye drops should be stored in a clean, dry area at room temperature, typically between 68°F and 77°F (20°C and 25°C). Protect the bottle from excessive heat, direct sunlight, and freezing conditions as these can affect the potency of the medication. Always keep the drops in their original container, tightly sealed, to maintain sterility and prevent contamination. Do not use the drops if the solution has changed color or become cloudy. Once the bottle is opened, write down the date and discard any remaining solution after 28 days to ensure the medication's effectiveness and safety. When it's time to dispose of the eye drops, do not pour them down the sink or flush them; instead, follow local guidelines for the safe disposal of medications to minimize environmental impact.

Following are the quick tips for Norfloxacin Drops:

• Wash your hands before and after applying the drops to maintain hygiene.
• Tilt your head back slightly and gently pull down the lower eyelid to create a pocket.
• Hold the dropper above the eye and squeeze a drop into the pocket.
• Close your eye gently and blink to distribute the drop evenly.
• Avoid touching the dropper tip to your eye or any surface to prevent contamination.
• If using other eye medications, wait at least 5 minutes between applications.
• Store the drops at room temperature, away from direct sunlight and moisture.