BEKSON FORT 250MCG INH

Beclomethasone, the active ingredient in Beclomethasone Spray, is a potent synthetic glucocorticoid that primarily exerts its anti-inflammatory effects by binding to cytoplasmic glucocorticoid receptors in target cells. Once bound, the drug-receptor complex translocates to the nucleus, where it regulates gene expression by inducing the synthesis of anti-inflammatory proteins and suppressing the production of pro-inflammatory mediators. This mechanism leads to a decrease in the release of inflammatory substances, such as histamine, leukotrienes, and cytokines, from various cell types involved in the inflammatory response. Specifically, beclomethasone inhibits the activity of immune cells, reduces the production of inflammatory enzymes, and suppresses the adhesion and migration of inflammatory cells to the site of inflammation, thereby reducing the symptoms associated with allergic and inflammatory conditions.

Beclomethasone

Corticosteroid spray

Spray

The following are the uses of Beclomethasone Spary:

• Used for reducing inflammation and swelling in the nose and sinuses, providing quick relief from nasal allergy symptoms.
• Used for treating allergic rhinitis and hay fever, effectively controlling symptoms like sneezing, itching, and a runny or blocked nose.
• Used for preventing the release of substances in the body that cause inflammation, thereby reducing nasal discomfort.
• Used for managing asthma symptoms when triggered by allergens, helping to open up the airways and breathe more easily.
• Used for providing localized treatment, ensuring direct action on the affected areas in the nasal passages.
• Used for both adults and children, offering a convenient and effective way to manage nasal allergies and asthma-related nasal issues.
• Used as a long-term treatment option to control and prevent allergy symptoms, especially for individuals with chronic conditions.

In the case of an overdose of Beclomethasone Spray, it is important to recognize the potential symptoms. These may include a rapid increase in heart rate, heightened blood pressure, and difficulty breathing. If an overdose is suspected, promptly seek medical advice or contact a healthcare professional. They will provide guidance on the necessary steps to address the situation and ensure appropriate treatment is administered to mitigate any adverse effects.

In the case of a missed dose of Beclomethasone Spray, it is important to administer the medication as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one. If you have missed multiple doses, consult your healthcare provider for guidance on how to get back on track with your medication regimen. It is crucial to maintain a consistent dosing schedule for the best treatment outcomes.

To use Beclomethasone Spray, gently shake the inhaler, exhale normally, place the mouthpiece in your mouth, inhale slowly while pressing down on the inhaler once, hold your breath for a few seconds, then remove the mouthpiece and exhale gently.

Here are the conditions and situations when Beclomethasone Spray should not be used:

• Do not use if you are allergic to Beclomethasone or any of the inactive ingredients in the spray.
• Avoid using if you have a recent history of nasal surgery or trauma.
• Not recommended for individuals with untreated nasal infections or recent nose bleeding.
• Contraindicated in patients with untreated tuberculosis.
• Should not be used if you have a fungal, bacterial, or viral infection in the nose or throat.
• Avoid using if you have a perforated nasal septum.
• Not suitable for individuals with untreated glaucoma or cataracts.
• Do not use if you have a history of hypersensitivity or severe reaction to corticosteroids.
• Should not be used in patients with untreated respiratory infections or active tuberculosis.
• Avoid using in individuals with immune system disorders or those taking immunosuppressant medications.

The side effects of Beclomethasone Spray may include:

• Sore throat
• Nasal irritation or dryness
• Nosebleeds
• Headache
• Unpleasant taste or smell
• Hoarseness of voice
• Cough
• Oral thrush (a fungal infection in the mouth or throat)

Following are the precautions and warnings for Beclomethasone Spray:

• This medication is for nasal use only and should not be sprayed into the eyes or mouth. Avoid spraying towards the middle of the nose to reduce the risk of nosebleeds.
• Beclomethasone is a corticosteroid and long-term use may lead to systemic absorption, which can cause adrenal suppression. Regular medical check-ups are necessary.
• Do not use this spray if you have recently had nasal surgery or an injury until your doctor advises it is safe.
• Wash your hands before and after use to avoid contamination.
• If you have a nasal infection or sores, consult your doctor before using this spray.
• Do not exceed the prescribed dosage, as it may increase the risk of side effects.
• Inform your doctor about all medications you are taking, especially other nasal sprays or corticosteroids.
• If you do not experience relief or your symptoms worsen, stop using the spray and seek medical advice immediately.

Following are the drug interactions for Beclomethasone Spray:

• Should not be used with other potent corticosteroids due to potential additive systemic effects and increased risk of adverse events.
• The use of Beclomethasone with ritonavir or cobicistat-containing products may result in increased systemic corticosteroid effects and should be avoided.
• Caution is advised when using Beclomethasone with ketoconazole, as it may increase the risk of systemic corticosteroid effects.
• Beclomethasone can interact with non-potassium sparing diuretics, potentially leading to hypokalemia.
• May reduce the efficacy of immunosuppressive drugs, such as cyclosporine, when used concurrently.
• It may increase the risk of systemic corticosteroid side effects when used with estrogen or oral contraceptives.
• Antifungal agents like ketoconazole and itraconazole can increase the systemic exposure of Beclomethasone.

Following are the food interactions to consider with Beclomethasone Spray:

• Avoid consuming grapefruit and grapefruit juice as they may interfere with the medication's metabolism, potentially leading to increased drug levels in the body.
• Limit alcohol consumption as it can increase the risk of gastrointestinal side effects, including stomach irritation and bleeding.
• Dairy products like milk and yogurt may reduce the absorption of Beclomethasone; consider separating these by a few hours.
• Avoid spicy foods, as Beclomethasone is used to treat respiratory conditions, and spicy foods may exacerbate symptoms like coughing and throat irritation.
• Hot beverages like coffee and tea may cause slight irritation when using the spray; it's advisable to use the spray before or after consuming hot drinks.
• No known significant interactions with vegetables, but ensure a balanced diet to support overall health.
• Always ensure adequate hydration by drinking enough water throughout the day while using Beclomethasone Spray.
• Consult your healthcare provider for personalized advice on dietary considerations during treatment.

Beclomethasone Spray should be stored properly to maintain its effectiveness and ensure safety. Keep the spray bottle in a cool, dry place, preferably at room temperature, and protect it from direct sunlight and moisture. Always keep the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. Avoid extreme temperatures by not storing it in hot or humid environments like the bathroom or kitchen. Regularly check the expiration date, and dispose of expired or unused spray responsibly; do not flush or pour it down the drain. Consult your pharmacist for guidance on proper disposal methods, and keep the medication away from children to prevent accidental exposure.

Following are the quick tips for Beclomethasone Spray:

• Wash your hands before using the spray to maintain hygiene.
• Shake the spray bottle well before each use to ensure proper mixing.
• Spray into the air first to test the mist, then inhale deeply and slowly.
• Coordinate your inhalation with the spray to ensure the medication reaches your lungs.
• Rinse your mouth with water after each use to minimize oral side effects.
• Clean the spray nozzle regularly to prevent blockage and ensure proper functioning.
• Store the spray at room temperature, away from direct sunlight and moisture.
• Keep a record of the number of sprays used to monitor your medication usage.