BENDROFLUAZIDE 2.5MG TAB IMP 28'S

BENDROFLUAZIDE 2.5MG TAB IMP 28'S

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  • Manufacturer IMPORTED
  • Generic Name

    Bendroflumethiazide 5MG

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Bendroflumethiazide is a thiazide diuretic that primarily acts by inhibiting the reabsorption of sodium and chloride ions in the early distal tubule of the nephron, a part of the kidney's filtration system. This inhibition occurs by binding to and blocking the thiazide-sensitive sodium-chloride symporter, which is responsible for the reabsorption of these ions. By promoting the loss of sodium and water, bendroflumethiazide increases urinary output, reduces extracellular fluid volume, and lowers blood pressure. The reduced reabsorption of sodium also leads to increased delivery of calcium to the distal tubule, resulting in enhanced calcium reabsorption, which is a secondary mechanism of action. This drug's effectiveness lies in its ability to enhance the elimination of sodium and water, thereby reducing blood volume and subsequently lowering blood pressure.

  • Ingredients

    Bendroflumethiazide 5MG

  • Drug Class

    Thiazide Diuretic

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Bendroflumethiazide 5MG Tablet:

    • Used for treating high blood pressure, helping to reduce the risk of strokes and heart attacks.
    • Used for managing fluid retention (edema) due to its diuretic effect, which increases urine production.
    • Used for managing certain kidney disorders, such as nephrotic syndrome, by reducing excess fluid buildup.
    • Used for controlling hypertension in patients with heart failure, improving symptoms and quality of life.
    • Used for managing calcium levels in hypercalcemia, a condition of elevated calcium in the blood.
    • Used for treating diabetes insipidus, a condition causing frequent urination and excessive thirst.
    • Used for managing ascites, the buildup of fluid in the abdomen, by promoting fluid removal.
  • In case of Overdose

    In the case of an overdose of Bendroflumethiazide 5MG Tablets, symptoms may include excessive urination, dehydration, and electrolyte imbalances. The severity of these symptoms can vary based on the amount ingested. Prompt medical attention is necessary, and healthcare professionals should be contacted immediately. Treatment may involve managing fluid and electrolyte levels and providing supportive care to address any complications arising from the overdose. Early intervention is crucial to prevent potential health risks.

  • Missed Dose

    In the case of a missed dose of Bendroflumethiazide 5MG Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for guidance on how to safely adjust your dosing regimen to ensure the medication's effectiveness.

  • How To Use

    To take Bendroflumethiazide 5MG Tablet, swallow the tablet whole with a glass of water, preferably in the morning, exactly as prescribed by your healthcare provider, without crushing or chewing it.

  • When Not to Use

    Here are the conditions or situations when Bendroflumethiazide 5MG Tablet should not be taken:

    • Should not be used in patients with known hypersensitivity or allergy to Bendroflumethiazide or other thiazide diuretics.
    • Contraindicated in individuals with severe kidney disease or those who are anuric (not producing urine).
    • Not recommended for patients with severe liver disease or progressive liver disorders.
    • Should not be used in individuals with Addison's disease (adrenal gland disorder).
    • Contraindicated during pregnancy, especially in the second and third trimesters.
    • Not suitable for breastfeeding mothers as it can pass into breast milk.
    • Should be avoided in patients with severe electrolyte imbalances, particularly low potassium levels (hypokalemia).
    • Not recommended for individuals with a history of gout or elevated uric acid levels.
    • Should not be used in patients with a history of systemic lupus erythematosus (SLE) as it may worsen the condition.
    • Contraindicated in patients with diabetes insipidus.
  • Side Effects

    The side effects of Bendroflumethiazide 5MG Tablet may include:

    • Increased urination
    • Low blood pressure (hypotension)
    • Muscle cramps
    • Weakness or fatigue
    • Dizziness or lightheadedness
    • Electrolyte imbalances (such as low potassium or sodium levels)
    • Skin rashes or itching
    • Gastrointestinal disturbances (e.g., nausea, diarrhea)
  • Precautions & Warnings

    Here are the precautions and warnings for Bendroflumethiazide 5MG Tablet:

    • This medication is not recommended for individuals with known allergies to bendroflumethiazide or other sulfonamide-derived drugs.
    • Patients with kidney or liver disease should use this medication with caution, as it may affect these organs. Regular monitoring is necessary.
    • Bendroflumethiazide can cause electrolyte imbalances, particularly low potassium and sodium levels. Regular blood tests are required to monitor these levels.
    • It may cause an increase in blood sugar levels, so diabetic patients should exercise caution and monitor their blood glucose regularly.
    • This drug may reduce blood pressure, which can lead to dizziness or lightheadedness, especially when standing up. Elderly patients should be cautious to avoid falls.
    • Patients with gout or a history of gout attacks should be aware that this medication may increase uric acid levels, potentially triggering a gout attack.
    • Bendroflumethiazide can make your skin more sensitive to sunlight. Avoid prolonged sun exposure and use protective measures when outdoors.
    • If you experience any unusual symptoms or side effects, such as severe dizziness, irregular heartbeat, or persistent nausea, consult your doctor immediately.
  • Drug Interactions

    Following are the drug interactions for Bendroflumethiazide 5MG Tablet:

    • Non-steroidal anti-inflammatory drugs (NSAIDs) may reduce the blood pressure-lowering effect of Bendroflumethiazide and increase the risk of kidney function impairment.
    • Bendroflumethiazide can enhance the effects of lithium and increase the risk of lithium toxicity. Close monitoring of lithium levels is necessary.
    • When combined with other antihypertensive medications, the blood pressure-lowering effect may be additive, potentially leading to hypotension.
    • The use of corticosteroids or ACTH (adrenocorticotropic hormone) with Bendroflumethiazide may increase the risk of hypokalemia and hypocalcemia.
    • It can decrease the elimination of digoxin, leading to higher digoxin levels and potential toxicity. Monitoring of digoxin levels is recommended.
    • Bendroflumethiazide may reduce the effectiveness of diabetic medications, including insulin, and increase blood sugar levels. Regular blood sugar monitoring is advised.
    • The use of non-potassium-sparing diuretics, including Bendroflumethiazide, with cardiac glycosides may cause cardiac arrhythmias due to potassium depletion.
  • Food Interactions

    Following are the food interactions for Bendroflumethiazide 5MG Tablet:

    • Avoid excessive salt (sodium) intake, including processed and canned foods, as it can reduce the effectiveness of the medication and worsen hypertension.
    • Potassium-rich foods like bananas, oranges, and spinach should be consumed to prevent potassium loss, which is a common side effect of thiazide diuretics.
    • Avoid alcohol consumption as it may increase the risk of dizziness and lightheadedness, especially when standing up from a sitting or lying position.
    • Grapefruit juice should be limited as it can interfere with the body's ability to metabolize Bendroflumethiazide, potentially leading to increased drug levels and side effects.
    • Maintain a consistent fluid intake to prevent dehydration, but avoid excessive fluid consumption, which may reduce the medication's effectiveness.
    • Avoid high-sugar foods and beverages as they can affect blood sugar levels, especially in diabetic patients.
    • Caffeine intake should be monitored as it can increase urination, potentially reducing the medication's effectiveness.
    • Always consult your healthcare provider for personalized dietary advice while taking this medication.
  • Storage/Disposal

    Bendroflumethiazide 5MG Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring they are kept away from direct sunlight, moisture, and heat. It is crucial to store the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. Remember to check the expiration date regularly and dispose of any expired or unused tablets appropriately. Avoid flushing them down the toilet or discarding them in drains; instead, consult a pharmacist or healthcare professional for guidance on safe disposal practices. Keep the medication securely stored and out of the reach of children to prevent accidental consumption.

  • Quick Tips, if any

    Following are the quick tips for Bendroflumethiazide 5MG Tablet:

    • Always take the tablet as directed by your doctor; do not alter the dosage without medical advice.
    • Bendroflumethiazide is typically taken once daily, preferably in the morning.
    • Swallow the tablet whole with a glass of water; do not crush or chew it.
    • Maintain a consistent daily routine for taking the medication.
    • Avoid consuming excessive amounts of salt or salty foods while on this medication.
    • Regularly monitor your blood pressure and blood electrolyte levels as advised by your doctor.
    • Do not stop taking the medication without consulting your doctor to prevent potential health complications.

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