Betagan (0.5%) 5ml Eye Drops

Levobunolol HCl drops act as a non-selective beta-adrenergic receptor antagonist, primarily targeting the beta-1 and beta-2 adrenergic receptors in the eye. By blocking these receptors, levobunolol reduces the production of aqueous humor, a fluid in the eye, by inhibiting the action of beta-adrenergic agonists. This decrease in aqueous humor production helps to lower intraocular pressure (IOP) by improving the outflow of fluid from the eye. The reduced IOP is crucial in managing conditions like glaucoma, where elevated eye pressure can damage the optic nerve.

Levobunolol HCL

Beta-blocker ophthalmic.

Drop

The following are the uses of Levobunolol HCL Drop:

• Used for treating open-angle glaucoma or ocular hypertension
• Used to reduce pressure in the eyes
• Used to lower the risk of vision loss or blindness
• Used for patients who have elevated intraocular pressure
• Used as a maintenance therapy to control eye pressure
• Used for long-term management of glaucoma
• Used to improve fluid drainage from the eyes
• Used to prevent optic nerve damage and other complications

In the case of an overdose of Levobunolol HCL Drops, it is important to remain calm and take immediate action. Contact a healthcare professional or poison control center for guidance. They will provide specific instructions based on the severity of the overdose and the individual's health condition. Common symptoms may include dizziness, fainting, and difficulty breathing, requiring prompt medical assessment.

In the case of a missed dose of Levobunolol HCL drops, it is recommended to administer the eye drops as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra drops to make up for the missed dose, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to adjust your medication regimen. It is important to adhere to the prescribed schedule to ensure the medication's effectiveness.

To administer Levobunolol HCl eye drops, gently tilt your head back, pull down the lower eyelid to create a pocket, and hold the dropper tip close to the eye without touching it; then, squeeze the prescribed number of drops into the pocket, blink gently to allow the medication to spread, and keep your eyes closed for 1-2 minutes to minimize drainage.

Here are the conditions or situations when Levobunolol HCl drops should not be used:

• If you have a known allergy or sensitivity to Levobunolol HCl or any other beta-blocker medications.
• Not recommended for individuals with severe heart failure or low heart rate (bradycardia).
• Contraindicated in patients with severe breathing problems or asthma, as it may worsen these conditions.
• Should not be used if you have a history of chronic obstructive pulmonary disease (COPD).
• Avoid using these drops if you have uncontrolled diabetes, as they can mask the symptoms of low blood sugar.
• Not suitable for individuals with a history of severe peripheral vascular disease.
• Do not use these drops if you have a condition called Prinzmetal's angina.
• Contraindicated during pregnancy or breastfeeding, unless the potential benefits outweigh the risks.
• Avoid using these drops if you have a history of kidney disease or severe kidney impairment.

The side effects of Levobunolol HCL Eye Drops may include:

• Stinging or burning sensation in the eyes
• Temporary blurred vision
• Eye irritation or redness
• Dry eyes
• Headache
• Dizziness
• Fatigue
• Increased sensitivity to light

Following are the precautions and warnings for Levobunolol HCl Eye Drops:

• Do not use if you are allergic to Levobunolol or any other ingredients in the eye drops.
• This medication is for ocular use only; do not swallow or inject.
• If you have a history of respiratory diseases like asthma or chronic obstructive pulmonary disease (COPD), use with caution as it may exacerbate these conditions.
• Patients with heart problems, especially bradycardia, heart block, or heart failure, should be closely monitored while using this medication.
• Levobunolol may cause a temporary decrease in visual acuity; avoid activities that require clear vision immediately after instilling the drops.
• Contact lenses should be removed before application and can be reinserted after 15 minutes to prevent lens absorption.
• Pediatric use should be under medical supervision; consult a doctor before using in children.
• Consult your doctor if you have a history of severe cardiovascular, pulmonary, or renal diseases before using Levobunolol.

Following are the drug interactions for Levobunolol HCl Drops:

• Concurrent use with other beta-blockers can lead to additive effects and increased risk of hypotension and bradycardia.
• Antihypertensive medications may have their effects enhanced, requiring close monitoring of blood pressure.
• Insulin or oral hypoglycemic agents may have their effects masked, potentially affecting blood glucose control.
• Levobunolol may decrease the intraocular pressure-lowering effect of other beta-blocker eye drops.
• The use of beta-agonists may be blunted, requiring careful monitoring in patients with asthma or COPD.
• Non-steroidal anti-inflammatory drugs (NSAIDs) might reduce the hypotensive effects of Levobunolol.
• Drugs that affect the metabolism of Levobunolol, such as CYP2D6 inhibitors, can increase its plasma levels.

Following are the food interactions to be aware of when using Levobunolol HCL Drops:

• Citrus fruits, especially grapefruit and its juice, should be avoided as they may interfere with the medication's metabolism, potentially altering its effectiveness.
• Alcohol consumption should be minimized as it can increase the risk of side effects, particularly affecting ocular pressure.
• Caffeine intake, from coffee, tea, or energy drinks, might need to be moderated as it can impact blood pressure and heart rate, which is relevant when using Levobunolol for glaucoma treatment.
• High-sodium foods should be consumed in moderation, as sodium can affect fluid retention and potentially impact eye pressure.
• A balanced diet rich in antioxidants, found in fruits and vegetables, can support overall eye health and complement the medication's effects.
• Staying well-hydrated is essential, but excessive fluid intake close to medication timing may affect absorption.
• Always consult your healthcare provider for personalized advice, as dietary considerations may vary based on individual health conditions.

Levobunolol HCL drops should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. Avoid exposure to extreme temperatures by keeping the medication away from heat sources like radiators or stoves. It is crucial to regularly check the expiration date, and any unused or expired drops should be disposed of carefully, avoiding flushing or pouring them down the drain. Consult a pharmacist or healthcare professional for appropriate disposal methods, and always keep medications securely stored away from children to prevent accidental ingestion.

Following are the quick tips for Levobunolol HCL Drops:

• Wash your hands before administering the eye drops to ensure cleanliness.
• Tilt your head back, gently pull down your lower eyelid, and instill the prescribed number of drops into the eye.
• Close your eyes gently and apply light pressure to the inner corner of the eye for a few seconds to prevent the medication from draining out.
• Avoid touching the dropper tip to your eye or any surface to prevent contamination.
• If you use other eye medications, wait at least 5-10 minutes before applying the next medication to avoid washout.
• Store the eye drops at room temperature, away from direct sunlight and extreme temperatures.
• Do not share your eye drops with others to prevent the spread of infection.