Betoxi (20mg) 20 Capsules

Piroxicam, a non-steroidal anti-inflammatory drug (NSAID), works by inhibiting both COX-1 and COX-2 enzymes, which are responsible for the production of prostaglandins. By blocking these enzymes, piroxicam reduces inflammation, pain, and fever. Beta-cyclodextrin, on the other hand, is a cyclic oligosaccharide that forms inclusion complexes with various molecules, including piroxicam. In the context of the 20mg capsule, beta-cyclodextrin likely serves as a carrier molecule, enhancing the solubility and bioavailability of piroxicam. This complex formation allows for improved absorption and potentially reduces side effects associated with traditional NSAID formulations. The beta-cyclodextrin molecule encapsulates piroxicam, protecting it from the gastrointestinal environment and facilitating its transport across biological membranes, leading to enhanced therapeutic efficacy.

NSAID (Non-Steroidal Anti-Inflammatory Drug)

Capsule

The following are the uses of Piroxicam, Beta Cyclodextrin 20mg Capsule:

• Used for reducing inflammation and relieving pain associated with arthritis, muscle sprains, and other painful conditions.
• Used to manage symptoms of osteoarthritis and rheumatoid arthritis.
• Effective in treating acute pain and swelling after injuries or surgeries.
• Can be used to reduce menstrual pain and discomfort.
• Provides relief from migraine headaches.
• Helps alleviate toothache and pain from dental procedures.
• Used for managing pain and inflammation in conditions like gout and ankylosing spondylitis.

In the case of an overdose of Piroxicam and Beta Cyclodextrin 20mg Capsules, prompt medical attention is necessary. Symptoms may include stomach pain, nausea, vomiting, and in severe cases, gastrointestinal bleeding. Seek emergency care and inform medical professionals about the overdose. They will provide appropriate treatment, which may include gastric lavage and supportive care to manage symptoms and prevent further complications.

In the case of a missed dose of Piroxicam, it is recommended to take the missed dose as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. For Beta Cyclodextrin 20mg Capsule, if you miss a dose, take it as soon as you remember, unless it's close to the time for your next dose. In this case, skip the missed dose and continue with your regular dosing regimen.

To take Piroxicam, Beta Cyclodextrin 20mg Capsule, swallow the capsule whole with a full glass of water, preferably with food, once or twice a day as directed by your healthcare professional, ensuring you follow the prescribed dosage and duration for optimal pain relief.

Following are the conditions when Piroxicam, Beta Cyclodextrin 20mg Capsule should not be used:

• Avoid if you are allergic to any non-steroidal anti-inflammatory drugs (NSAIDs) or have experienced asthma attacks, hives, or other allergic reactions after taking aspirin or other NSAIDs.
• Do not use if you have a history of gastrointestinal bleeding or perforation caused by NSAIDs.
• Contraindicated in individuals with severe kidney or liver disease.
• Should not be used by patients with a history of heart attack, stroke, or blood clots.
• Avoid if you are scheduled for heart bypass surgery (or similar procedures).
• Not recommended for individuals with severe dehydration or low fluid volume.
• Do not use if you are in the third trimester of pregnancy.
• Should not be used by breastfeeding mothers.
• Avoid if you have uncontrolled high blood pressure.

The side effects of Piroxicam, Beta Cyclodextrin 20mg Capsule may include:

• Stomach pain or discomfort
• Nausea and vomiting
• Diarrhea or constipation
• Dizziness or vertigo
• Headache
• Skin rash or itching
• Increased blood pressure
• Fluid retention and swelling in the lower legs

Following are the precautions and warnings for Piroxicam, Beta Cyclodextrin 20mg Capsule:

• This medication should be used with caution in patients with a history of gastrointestinal bleeding, ulcers, or other stomach disorders, as it may increase the risk of gastrointestinal side effects.
• Patients with cardiovascular disease or risk factors should be closely monitored, as Piroxicam may increase the risk of heart attack or stroke.
• It is important to avoid using this medication during pregnancy, especially in the third trimester, as it may cause potential harm to the fetus.
• Beta Cyclodextrin can cause kidney-related issues; patients with pre-existing kidney problems should exercise caution and regular monitoring is advised.
• The use of this medication may increase the risk of bleeding, especially in patients with bleeding disorders or those taking anticoagulants.
• Elderly patients may be more susceptible to the side effects of this medication, particularly gastrointestinal bleeding and kidney problems.
• Piroxicam may cause severe allergic reactions; immediate medical attention is required if symptoms such as rash, itching, swelling, or difficulty breathing occur.
• It is recommended to discontinue the medication before any surgical procedures due to the increased risk of bleeding.

Following are the drug interactions for Piroxicam, Beta Cyclodextrin 20mg Capsule:

• Concurrent use with other NSAIDs or aspirin may increase the risk of gastrointestinal bleeding and ulcers.
• Piroxicam can reduce the effectiveness of diuretics and antihypertensive medications, requiring close monitoring of blood pressure.
• Lithium levels may be elevated when used with Piroxicam, increasing the risk of lithium toxicity.
• Anticoagulants like warfarin may have their effects enhanced by Piroxicam, requiring close monitoring of coagulation parameters.
• Methotrexate levels may be increased, potentially leading to methotrexate toxicity.
• Piroxicam may decrease the elimination of medications metabolized by the kidneys, leading to increased drug levels and potential toxicity.
• The risk of nephrotoxicity may be increased when used with other nephrotoxic drugs.

Following are the food interactions for Piroxicam, Beta-Cyclodextrin 20mg Capsule:

• Alcohol consumption should be avoided or limited as it may increase the risk of gastrointestinal bleeding and liver toxicity when combined with Piroxicam.
• Avoid grapefruit and grapefruit juice as they can interfere with the metabolism of Piroxicam, potentially leading to increased drug levels in the body.
• High-fat meals may delay the absorption of Piroxicam, so it is best to take the medication on an empty stomach or with a light meal.
• Salt substitutes containing potassium should be used cautiously as Piroxicam may increase potassium levels in the body.
• Limit the intake of foods rich in vitamin K (like leafy greens) as Piroxicam may affect blood clotting.
• Caffeine-rich beverages like coffee and energy drinks may increase the risk of caffeine sensitivity when taken with Beta-Cyclodextrin.
• Beta-Cyclodextrin may decrease the absorption of fat-soluble vitamins (A, D, E, and K), so ensure a balanced diet to maintain adequate vitamin levels.
• Avoid excessive consumption of foods with high tyramine content (aged cheeses, cured meats) as Beta-Cyclodextrin may interact with tyramine, leading to potential blood pressure issues.

Piroxicam, Beta Cyclodextrin 20mg Capsules should be stored in a cool, dry area, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial to keep this medication away from heat sources like radiators or stoves, as temperature fluctuations can impact its effectiveness. Always adhere to the expiration date on the packaging, and for safe disposal, avoid flushing or pouring it down the drain. Consult a pharmacist or healthcare professional for appropriate disposal methods, and keep the capsules out of children's reach to prevent accidental consumption. Proper storage and disposal practices are essential to maintain the medication's quality and ensure safety.

Following are the quick tips for Piroxicam and Beta Cyclodextrin 20mg Capsule:

• Consult your doctor before use, especially if you have a history of stomach ulcers or kidney problems.
• Swallow the capsule whole with a full glass of water to ensure proper absorption.
• Take the capsule with food to reduce the risk of stomach irritation.
• Maintain a consistent dosing schedule for maximum effectiveness.
• Do not crush or chew the capsule; it is designed for extended release.
• Inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.