Bexus (750mg) 10 Tablets

Levofloxacin 750mg Tablet works primarily by inhibiting a specific type of enzyme called DNA gyrase, which is essential for bacterial DNA replication and transcription. This antibiotic selectively targets the A subunit of DNA gyrase, forming a stable drug-enzyme-DNA complex. By doing so, it prevents the bacterial DNA from unwinding and replicating, ultimately leading to bacterial cell death. The mechanism of action is specifically tailored to affect bacterial cells, as eukaryotic cells, including human cells, do not have DNA gyrase. This selective targeting contributes to the antibiotic's effectiveness in treating bacterial infections.

Levofloxacin 750mg

Fluoroquinolone antibiotic.

Tablet

The following are the uses of Levofloxacin 750mg Tablet:

• Used for treating severe bacterial infections like pneumonia, bronchitis, and urinary tract infections.
• Used for its effectiveness against a wide range of bacteria, including those resistant to other antibiotics.
• Used for patients with kidney or liver problems, as it is eliminated from the body mainly through these organs.
• Used as a last-resort treatment option for infections caused by multidrug-resistant bacteria.
• Used for preventing the progression of certain infections, especially in high-risk patients.
• Used for its ability to penetrate well into various body tissues and fluids, ensuring effective treatment.
• Used under strict medical supervision due to potential side effects and drug interactions.
• Used for specific bacterial strains as determined by sensitivity testing.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For adults with community-acquired pneumonia, the recommended dose is 500 mg once daily for 5 to 7 days.
• For adults with chronic bacterial prostatitis, the recommended dose is 750 mg once daily for 7 days.
• For adults with acute exacerbation of chronic bronchitis, the recommended dose is 500 mg once daily for 5 days.

In the case of an overdose of Levofloxacin 750mg Tablets, it is important to recognize the potential severity of this situation. Symptoms may include dizziness, nausea, and a rapid heart rate. If an overdose is suspected, immediate action should be taken. Contact a healthcare professional or seek emergency medical assistance without delay. Prompt treatment can help mitigate the risks associated with an overdose and ensure appropriate medical care. It is crucial to act swiftly to address any potential health complications.

In the case of a missed dose of Levofloxacin 750mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may recommend adjusting your dosage or provide specific instructions to ensure you receive the full course of treatment.

To take Levofloxacin 750mg Tablet, swallow the tablet whole with a full glass of water, ensuring you complete the full course as prescribed by your healthcare provider, typically taken once daily or as directed.

Following are the conditions when Levofloxacin 750mg Tablet should not be used:

• Must not be used in individuals with a known allergy to Levofloxacin or other quinolone antibiotics.
• Not suitable for individuals with a history of myasthenia gravis, as it can worsen muscle weakness.
• Contraindicated in patients with a history of tendon disorders or tendon rupture related to previous quinolone therapy.
• Should not be used in individuals with a history of epilepsy or seizures, as it may lower the seizure threshold.
• Must be avoided in patients with prolonged QT intervals or heart rhythm disorders.
• Not recommended for individuals with severe kidney disease without adjusting the dose.
• Contraindicated in pregnant and breastfeeding women due to potential risks to the fetus and infant.
• Should not be used in children and adolescents, as it can cause permanent damage to growing bones and joints.

The side effects of Levofloxacin 750mg Tablet may include:

• Nausea and vomiting
• Diarrhea
• Headache
• Dizziness
• Insomnia (difficulty sleeping)
• Skin rash or itching
• Joint or muscle pain
• Tendinitis or tendon rupture (rare but serious)

Following are the precautions and warnings for Levofloxacin 750mg Tablet:

• This medication is intended for serious bacterial infections and should not be used for minor illnesses like the common cold or flu.
• Allergic reactions can occur; seek medical attention if you experience severe rashes, itching, swelling, or difficulty breathing.
• May cause tendonitis or tendon rupture, especially in those over 60, athletes, or those taking corticosteroids; report any tendon pain or discomfort.
• Can affect the central nervous system, causing dizziness or lightheadedness; exercise caution when performing tasks that require alertness.
• May cause diarrhea; contact your doctor if it becomes severe or persistent, as it could be a sign of a more serious condition.
• Avoid excessive sunlight or UV exposure as Levofloxacin may increase sensitivity to sunlight.
• Inform your healthcare provider of your medical history, especially kidney or liver disease, as dosage adjustments may be necessary.
• Not recommended for use in pregnant or breastfeeding women unless the potential benefits outweigh the risks.

Following are the drug interactions for Levofloxacin 750mg Tablet:

• Avoid concomitant use with other fluoroquinolones or drugs that prolong the QT interval, such as antiarrhythmics, as this may increase the risk of cardiac arrhythmias.
• The effectiveness of oral antidiabetic drugs or insulin may be altered, requiring careful blood glucose monitoring.
• Levofloxacin can enhance the effects of warfarin and other anticoagulants, potentially leading to bleeding risks. Regular monitoring of coagulation parameters is necessary.
• Non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of central nervous system (CNS) stimulation and seizures when used with Levofloxacin.
• The absorption of Levofloxacin can be reduced by certain antacids, sucralfate, and multivitamins containing zinc, calcium, magnesium, or iron.
• Probenecid and cimetidine may increase Levofloxacin levels, potentially leading to increased side effects.
• Theophylline levels may be elevated when used with Levofloxacin, requiring dosage adjustments.

Following are the food interactions for Levofloxacin 750mg Tablet:

• Avoid consuming dairy products (like milk, yogurt, cheese) and calcium-fortified foods/drinks within 2 hours before or after taking Levofloxacin. Calcium can bind to the drug, reducing its absorption.
• Iron supplements, multivitamins with minerals, and products high in iron (like spinach, red meat) should be avoided within 2 hours of taking this medication as iron can hinder its absorption.
• Antacids containing magnesium or aluminum should be separated by at least 2 hours from Levofloxacin dose, as they can decrease its effectiveness.
• Avoid caffeine or limit its consumption while on Levofloxacin, as it can intensify the drug's side effects like nervousness, insomnia, and rapid heart rate.
• Grapefruit and grapefruit juice should be avoided as they can increase the levels of Levofloxacin in the blood, potentially leading to increased side effects.
• Alcohol may intensify the drug's side effects and should be consumed in moderation or avoided.
• Consume a balanced diet rich in fiber and maintain hydration to prevent gastrointestinal side effects associated with Levofloxacin.
• Always follow the dosage instructions provided by your healthcare professional for optimal effectiveness and safety.

Levofloxacin 750mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial to avoid exposing the tablets to heat sources, including stoves or radiators, as temperature fluctuations can impact their effectiveness. Always check the expiration date, and if the medication has expired or is no longer needed, proper disposal is essential. Do not dispose of it in wastewater or household garbage; instead, follow local guidelines or consult a healthcare professional for safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Levofloxacin 750mg Tablet:

• Take the tablet as directed by your doctor; do not crush or chew it.
• Ensure you complete the full prescribed course, even if you feel better early.
• Maintain adequate fluid intake while taking this medication.
• Avoid excessive sunlight and use sunscreen when outdoors during treatment.
• Inform your doctor if you have a history of tendon disorders or myasthenia gravis.
• Do not drive or operate machinery if you experience dizziness or blurred vision.
• Store the tablets at room temperature, away from moisture and light.

Levofloxacin is an antibiotic used to treat bacterial infections, however, it may cause side effects in some individuals. It is crucial to monitor your health while taking this medication to ensure its effectiveness and safety. Your doctor may recommend specific lab tests before and during treatment with Levofloxacin to monitor for these side effects. These tests include a Complete Blood Count to monitor any decrease in white blood cell counts, which can cause bone marrow suppression or neutropenia. Liver Function Tests may be performed to monitor liver enzyme levels to ensure the drug is not causing undue stress on the liver. Prolonged use of Levofloxacin can lead to mild impairment of kidney function, thus Kidney Function Tests may be recommended to measure blood levels of sodium, potassium, creatinine, and BUN. Additional tests may be required based on individual health conditions and other factors. It is important to discuss with your doctor the relevance of these tests to your treatment, and the importance of adhering to the recommended dosage and duration of treatment to minimize risks and achieve the best outcome.