Biflocin (250mg) 25ml Suspension

Flucloxacillin 250mg syrup/suspension acts by inhibiting the synthesis of bacterial cell walls. It specifically targets penicillin-binding proteins (PBPs) in susceptible bacteria, primarily Gram-positive organisms. By binding to these PBPs, flucloxacillin prevents the cross-linking of peptidoglycan strands, which is essential for the structural integrity of the bacterial cell wall. This disruption weakens the cell wall, leading to cell lysis and ultimately the death of the bacteria. Flucloxacillin is particularly effective against Staphylococcus species, including methicillin-sensitive Staphylococcus aureus (MSSA), as it is resistant to beta-lactamase enzymes produced by these bacteria, allowing it to maintain its antibacterial activity.

Flucloxacillin 250mg

Penicillin-based antibiotic

Suspension

The following are the uses of Flucloxacillin 250mg Syrup/Suspension:

• Used for treating bacterial infections such as pneumonia, skin infections, and bone infections.
• Used for respiratory tract infections like bronchitis and tonsillitis.
• Effective against staphylococcal bacteria, including those resistant to other antibiotics.
• Ideal for patients who cannot take medication orally, providing a convenient alternative.
• Suited for children or those who prefer a liquid medication.
• Provides a targeted treatment approach for specific bacterial strains.
• Helps prevent the spread of infection and promotes faster recovery.
• May be used as an alternative for patients allergic to penicillin.

In the case of an overdose of Flucloxacillin 250mg Syrup/Suspension, individuals may experience gastrointestinal symptoms such as nausea, vomiting, and diarrhea. Additionally, an overdose could potentially lead to more severe reactions, including allergic responses and an increased risk of developing antibiotic-resistant bacteria. It is important to promptly seek medical advice if an overdose is suspected, as healthcare professionals can provide appropriate guidance and treatment options.

In the case of a missed dose of Flucloxacillin 250mg Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed with your medication regimen.

To administer Flucloxacillin 250mg Syrup/Suspension, shake the bottle well, then use the provided measuring device or oral syringe to measure the prescribed dose, which should be taken orally, preferably at evenly spaced intervals, with or without food, as directed by your healthcare professional.

Here are the conditions or situations when Flucloxacillin 250mg Syrup/Suspension should not be used:

• Do not use if you have a known allergy or hypersensitivity to Flucloxacillin, penicillin, or any other beta-lactam antibiotics.
• Avoid if you have a history of severe allergic reactions, especially to cephalosporins or penicillin-derived medications.
• Should not be used in patients with a history of liver disease or severe kidney impairment.
• Not recommended for individuals with mononucleosis or lymphatic leukemia.
• Contraindicated in patients with a history of gastrointestinal diseases, especially those with a history of regional enteritis or ulcerative colitis.
• Do not use if you have a history of jaundice or hepatitis after taking Flucloxacillin or any other penicillin-based medication.
• Avoid in newborn babies, especially premature babies, due to the risk of displacing bilirubin from protein binding sites.

The side effects of Flucloxacillin 250mg Syrup/Suspension may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain or discomfort
• Skin rashes or itching
• Allergic reactions (such as hives, swelling, or difficulty breathing)
• Headache
• Dizziness
• Changes in liver function (rare)

Following are the precautions and warnings for Flucloxacillin 250mg Syrup/Suspension:

• This medication should not be used if you are allergic to Flucloxacillin or any penicillin-type antibiotics.
• Patients with a history of kidney or liver disease should use this medication with caution, and regular monitoring of liver and kidney function is recommended during treatment.
• Flucloxacillin can cause diarrhea, and in rare cases, it may indicate a new infection. If severe diarrhea occurs, stop the medication and seek medical advice.
• Long-term or repeated use of Flucloxacillin may result in oral thrush or a new yeast infection. Contact your doctor if you notice white patches in your mouth or any other unusual symptoms.
• Avoid taking other antibiotics in combination with Flucloxacillin unless prescribed by your doctor.
• Ensure the medication is well-shaken before each use to ensure a consistent dose.
• Store the medication in a cool, dry place, away from direct sunlight, and keep it out of reach of children.
• Inform your doctor if you have any other medical conditions or are taking any other medications to ensure safe and effective use.

Following are the drug interactions for Flucloxacillin 250mg Syrup/Suspension:

• Probenecid can increase the concentration of Flucloxacillin, potentially enhancing its effects and side effects.
• Combined use with other antibiotics like Chloramphenicol or Rifampicin may reduce Flucloxacillin's effectiveness.
• The effects of oral anticoagulants like Warfarin can be enhanced, increasing the risk of bleeding.
• Flucloxacillin may reduce the absorption of oral contraceptives, potentially reducing their effectiveness.
• It can decrease the effectiveness of Methotrexate, a drug used in cancer and autoimmune diseases.
• Live bacterial vaccines may not work as well during and shortly after Flucloxacillin treatment.
• May alter the effectiveness of medications affected by stomach pH, such as certain antifungals and antivirals.

Following are the food interactions for Flucloxacillin 250mg Syrup/Suspension:

• Flucloxacillin should be taken with food to reduce the risk of stomach upset and improve absorption.
• Avoid alcohol consumption during the course of treatment as it may cause liver-related side effects and increase the risk of gastrointestinal issues.
• Dairy products like milk, cheese, and yogurt may interfere with the absorption of Flucloxacillin, so consider taking the medication at least 2 hours before or after consuming dairy.
• Grapefruit and grapefruit juice should be avoided as they can affect the metabolism of Flucloxacillin, potentially leading to increased blood levels and side effects.
• High-fat meals can delay the absorption of Flucloxacillin, so it is best to take the medication on an empty stomach or with a light meal.
• Avoid consuming iron supplements, multivitamins, or iron-rich foods (like red meat, spinach) within 2 hours of taking Flucloxacillin as they can reduce its effectiveness.
• Vitamin K-rich foods like leafy greens (broccoli, spinach) and soybean products may interact with Flucloxacillin, affecting blood clotting, so consult your doctor for dietary advice.
• Always follow the dosage instructions provided by your healthcare professional, and inform them about any dietary concerns or potential food interactions.

Flucloxacillin 250mg Syrup/Suspension should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the medication securely sealed in its original container to maintain its integrity. Avoid storage in bathrooms or near heat-emitting appliances to prevent degradation. Regularly check the expiration date, and when disposing of the medication, do not flush or pour it down the drain. Instead, consult a pharmacist or healthcare professional for appropriate disposal methods, ensuring that the medication is kept away from children to prevent accidental consumption.

Following are the quick tips for Flucloxacillin 250mg Syrup/Suspension:

• Always complete the full course of medication as prescribed by your doctor.
• Administer the syrup as directed by your healthcare professional for best results.
• Shake the bottle vigorously before each use to ensure proper mixing.
• Use the provided measuring cup or oral syringe for accurate dosing.
• Take the syrup with a full glass of water to aid in swallowing.
• Store the medication at room temperature, away from direct sunlight and moisture.
• Regularly monitor your condition and inform your doctor if symptoms persist or worsen.