Biflocin (500mg) 20 Capsules

Flucloxacillin 500mg capsules work by inhibiting the synthesis of peptidoglycan, a crucial component of the bacterial cell wall. It achieves this by binding to and inhibiting the action of penicillin-binding proteins (PBPs) in susceptible bacteria, primarily Gram-positive organisms. By preventing the cross-linking of peptidoglycan chains, flucloxacillin weakens the cell wall, leading to cell lysis and bacterial death. This mechanism of action is selective for bacteria as it targets processes specific to bacterial cell wall synthesis, which are not present in human cells.

Flucloxacillin 500mg

Penicillin antibiotic

Capsule

The following are the uses of Flucloxacillin 500mg Capsule:

• Used for treating bacterial infections such as pneumonia, cellulitis, and boils.
• Used for skin and soft tissue infections caused by susceptible bacteria.
• Used for bone and joint infections requiring a penicillin-type antibiotic.
• Used for endocarditis (heart valve infection) when caused by sensitive bacteria.
• Used for preventing infection during major dental work in patients at risk.
• Used for controlling and eliminating beta-lactamase-producing bacteria.
• Used for patients with a history of allergy to penicillins as a treatment option.

In the case of an overdose of Flucloxacillin 500mg Capsules, individuals may experience an array of symptoms. These can include gastrointestinal issues such as nausea, vomiting, and diarrhea, as well as more severe reactions like seizures, confusion, and abnormal liver function. Promptly recognizing and addressing an overdose is crucial, as it may lead to serious health complications. Medical professionals should be consulted immediately to determine the best course of action, which may involve supportive care and monitoring to ensure the patient's well-being.

In the case of a missed dose of Flucloxacillin 500mg Capsule, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication.

To take Flucloxacillin 500mg Capsule, swallow the capsule whole with a full glass of water, ensuring you complete the full course as prescribed by your healthcare provider, typically four times a day at evenly spaced intervals.

Here are the circumstances when Flucloxacillin 500mg Capsule should not be taken:

• Avoid if allergic to Flucloxacillin, any other penicillin antibiotics, or any ingredients in the capsule formulation.
• Not suitable for individuals with a history of severe allergic reactions to any other antibiotics, especially cephalosporins.
• Should not be used in patients with a previous history of liver problems or jaundice caused by Flucloxacillin.
• Contraindicated in patients with severe kidney disease, as dosage adjustments may not be sufficient.
• Not recommended for individuals with a history of gastrointestinal diseases, especially colitis.
• Avoid in patients with mononucleosis or lymphatic leukemia, as it may cause skin rashes.
• Do not use in patients with a history of severe or life-threatening allergic reactions to other beta-lactam antibiotics.

The side effects of Flucloxacillin 500mg Capsule may include:

• Nausea and vomiting
• Diarrhea
• Stomach pain or cramps
• Skin rash or itching
• Allergic reactions (e.g., hives, difficulty breathing, swelling of the face/lips/tongue)
• Dark urine or jaundice (yellowing of the skin and eyes)
• Vaginal itching or discharge
• Headache

Following are the precautions and warnings for Flucloxacillin 500mg Capsule:

• Do not take this medication if you have a known allergy to penicillin or any other beta-lactam antibiotics.
• Caution is advised for patients with a history of gastrointestinal problems, especially colitis, as this medication may cause gastrointestinal disturbances.
• It should be used with caution in individuals with kidney or liver disease, as dosage adjustments may be necessary.
• Inform your doctor if you have a history of allergies, asthma, or hay fever as this medication may cause allergic reactions.
• Prolonged use may lead to the overgrowth of non-susceptible bacteria or fungi, and repeated evaluations are essential.
• If you develop a skin rash, persistent diarrhea, or any other severe side effects, stop taking the medication and seek medical advice immediately.
• Flucloxacillin may reduce the effectiveness of hormonal contraceptives, so alternative contraceptive methods are recommended during treatment.
• Elderly patients may be more susceptible to adverse reactions, particularly those with kidney or liver impairment.

Following are the drug interactions for Flucloxacillin 500mg Capsule:

• Flucloxacillin may increase methotrexate levels, requiring dose adjustment.
• Regular monitoring of INR is advised as Flucloxacillin can affect the metabolism of warfarin.
• It may increase Flucloxacillin blood levels by reducing its excretion.
• Flucloxacillin can reduce the effectiveness of oral contraceptives, requiring additional contraceptive measures.
• Flucloxacillin may increase the risk of baclofen side effects.
• May decrease Flucloxacillin effectiveness, potentially leading to antibiotic resistance.
• Increased risk of skin reactions when used together.

Following are the food interactions for Flucloxacillin 500mg Capsule:

• Avoid excessive alcohol consumption during the treatment period as it may increase the risk of liver-related side effects and reduce the effectiveness of the medication.
• Maintain a balanced diet to support overall health and recovery. Adequate nutrition can aid in fighting infections and promoting healing.
• Ensure proper hydration by drinking enough fluids, especially water, to maintain kidney function and facilitate the elimination of the drug and its metabolites.
• There are no specific food restrictions with Flucloxacillin, but it is generally advisable to avoid consuming large amounts of dairy products close to medication intake, as calcium can potentially interfere with antibiotic absorption.
• Consume a varied diet rich in vitamins and minerals to support immune function and overall well-being during the course of treatment.
• If you have any dietary restrictions or preferences, consult your healthcare provider to ensure they are compatible with the medication's effectiveness.
• Flucloxacillin can be taken with or without food, but if stomach upset occurs, taking it with food may help alleviate gastrointestinal discomfort.

Flucloxacillin 500mg Capsules should be stored in a dry and cool place, preferably at room temperature, ensuring protection from direct sunlight and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial to keep this medication away from heat sources like radiators or stoves, as extreme temperatures can impact its effectiveness. Always check the expiration date, and if the capsules are no longer needed or have expired, proper disposal is essential. Avoid flushing them down the toilet or sink; instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep Flucloxacillin capsules out of children's reach to prevent accidental consumption.

Following are the quick tips for Flucloxacillin 500mg Capsule:

• Swallow the capsule whole with a full glass of water to ensure proper absorption.
• Take the capsule as directed by your doctor, typically 1 to 4 times a day, at evenly spaced intervals.
• You can take Flucloxacillin with or without food, but taking it with food may help prevent stomach upset.
• Complete the full course of medication as prescribed, even if you feel better after a few days.
• If you have difficulty swallowing capsules, you can open the capsule and mix the contents with a small amount of soft food like applesauce or yogurt.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.
• Regularly monitor your health and inform your doctor if your condition does not improve or worsens.