Bifomyk (1%) 15g Cream

Bifonazole, the active ingredient in Bifonazole Cream, is an antifungal agent that primarily targets dermatophytes, yeasts, and other fungi responsible for skin infections. Its mechanism of action involves inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes. By binding to the fungal enzyme lanosterol 14α-demethylase, Bifonazole blocks the conversion of lanosterol to ergosterol, which results in the disruption of membrane integrity and function. This interference in the fungal cell membrane synthesis leads to the accumulation of toxic levels of 14α-methyl sterols, causing the fungal cell's growth to cease and eventually leading to its death. This selective action against fungal cells makes Bifonazole an effective treatment for various superficial fungal infections.

Bifonazole

Imidazole antifungal.

Cream

The following are the uses of Bifonazole Cream:

• Used for treating fungal skin infections like athlete's foot, ringworm, and jock itch.
• Used for relieving itching, redness, and inflammation caused by fungal growth.
• Used for preventing fungal infections, especially in sweaty or humid environments.
• Used for managing fungal infections that may occur in skin folds or intimate areas.
• Used for maintaining skin health by eliminating harmful fungi.
• Used for restoring the natural skin barrier function disrupted by fungal infections.
• Used for providing targeted relief from fungal-related skin discomfort.
• Used for complementing overall skin care routines in cases of fungal issues.

In the case of an overdose of Bifonazole Cream, it is important to remain calm and seek medical advice promptly. While the cream is generally safe, excessive use can lead to skin irritation and discomfort. Symptoms of an overdose may include redness, itching, or a burning sensation at the application site. If ingested, it may cause nausea, stomach discomfort, or diarrhea. It is advisable to contact a healthcare professional or a poison control center for guidance on managing the situation effectively.

In the case of a missed dose of Bifonazole Cream, it is important to apply the medication as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra cream to make up for the missed application. If you have missed multiple doses, contact your healthcare provider for guidance, as they may recommend adjusting your dosage schedule to ensure the treatment's effectiveness. Remember, it is essential to adhere to the prescribed treatment plan for optimal results.

To apply Bifonazole Cream, clean and dry the affected skin area, then apply a thin layer of the cream, gently rubbing it into the skin, usually twice a day or as directed by your healthcare professional.

Following are the conditions or circumstances when Bifonazole Cream should not be applied:

• Must not be used if you are allergic to Bifonazole or any other similar antifungal medications.
• Avoid using on skin areas with open wounds, severe burns, or severe skin injuries.
• Not suitable for individuals with a history of skin reactions or sensitivity to the cream's ingredients.
• Do not use Bifonazole Cream on skin areas affected by other skin conditions like psoriasis or severe eczema.
• Avoid using near the eyes, mouth, or other mucous membranes.
• Discontinue use and consult a doctor if irritation or allergy symptoms develop after application.

The possible side effects of Bifonazole Cream may include:

• Skin irritation at the application site
• Redness or erythema
• Itching or pruritus
• Burning sensation
• Dry skin
• Allergic contact dermatitis
• Skin peeling or exfoliation
• Mild rash

Following are the precautions and warnings for Bifonazole Cream:

• Avoid using Bifonazole Cream on open wounds, burns, or severely damaged skin. It is intended for external use only.
• Discontinue use and consult a doctor if irritation, redness, or swelling occurs at the application site.
• Wash your hands thoroughly after applying the cream to avoid accidental contact with eyes, nose, or mouth.
• Do not use this medication for conditions other than those prescribed by your doctor.
• Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as they may advise caution or alternative treatments.
• Keep the cream out of reach of children. If accidental ingestion occurs, seek immediate medical attention.
• Do not share this medication with others, even if they have similar symptoms, as it may be inappropriate for their condition.

Following are the drug interactions for Bifonazole Cream:

• No significant drug interactions have been reported with Bifonazole Cream, but it may reduce the effectiveness of other topical medications if applied simultaneously.
• It is advisable to avoid using other antifungal or steroid-based creams at the same time without medical advice.
• Bifonazole may interact with oral antifungal medications, potentially increasing the risk of liver-related side effects.
• Combining with certain medications that affect the immune system may lead to altered skin reactions.
• Avoid using other medicated creams or ointments on the same area without consulting a healthcare professional.
• Bifonazole could potentially interact with systemic medications, especially those metabolized by the liver, leading to increased side effects.
• Topical application of Bifonazole may increase skin sensitivity to sunlight, so caution is advised when using alongside photosensitizing drugs.

Following are the food interactions to be aware of when using Bifonazole Cream:

• Bifonazole may interact with certain foods, although these interactions are not well-documented. It is generally recommended to avoid consuming excessive amounts of fatty or oily foods during treatment, as they may affect the absorption of the medication through the skin.
• Avoid citrus fruits and juices, such as oranges, lemons, and grapefruits, as they may cause skin irritation when used in conjunction with Bifonazole.
• Alcohol-containing products like toners or astringents might increase skin dryness and irritation, so it's best to avoid them.
• Inform your doctor if you regularly consume caffeine-rich beverages like coffee or tea, as these may potentially impact the skin's sensitivity.
• Spicy foods can sometimes cause sweating, which might lead to skin irritation in the treated areas, so consider reducing spicy food intake.
• While not a food, it's important to note that Bifonazole may react with other topical medications, so consult your healthcare provider before using any other creams or ointments.
• Always follow the instructions provided by your healthcare professional regarding the use of Bifonazole Cream and any dietary considerations.

Bifonazole Cream should be stored in a cool and dry location, preferably in its original container, ensuring a tight seal to prevent contamination. Maintain storage away from direct sunlight, heat sources like radiators or stoves, and moisture-prone areas like bathrooms, as these conditions can compromise the cream's integrity. Check the packaging for the expiration date, and if the cream is past its prime or no longer needed, do not flush it down the toilet or drain. Instead, consult a pharmacist or healthcare professional for guidance on proper disposal methods. It is crucial to keep this medication out of children's reach to prevent accidental ingestion.

Following are the quick tips for Bifonazole Cream:

• Apply a thin layer of the cream to the affected area, gently rubbing it into the skin.
• Wash and dry the affected area before application for better absorption.
• Use the cream as directed by your doctor, typically twice a day, morning and evening.
• Continue using the cream for the full prescribed duration, even if symptoms improve.
• Avoid covering the treated area with tight clothing or bandages to allow the skin to breathe.
• Do not apply the cream near your eyes, mouth, or open wounds.
• Store the cream at room temperature, away from direct sunlight and moisture.