Biopred 5ml Eye Suspension

The combined medication Neomycin [0.5 %w/v], Polymyxin B (Sulphate) [10,000 IU/ml], and Prednisolone and Prednisone [0.5 %w/v] Eye Syrup/Suspension exhibits a synergistic mechanism of action to combat eye infections and reduce inflammation. Neomycin, an aminoglycoside antibiotic, binds to bacterial ribosomes, disrupting protein synthesis and effectively targeting a broad spectrum of bacteria. Polymyxin B, a cyclic polypeptide antibiotic, disrupts the integrity of the bacterial cell membrane, leading to cell death, particularly against Gram-negative bacteria. Prednisolone and Prednisone, synthetic corticosteroids, exert their anti-inflammatory effects by inhibiting the production of inflammatory mediators, reducing leukocyte migration, and suppressing the immune response in the eye. Together, this combination therapy provides both antimicrobial and anti-inflammatory benefits for the treatment of ocular infections and inflammatory conditions.

Antibiotic, Corticosteroid

Drop

The following are the uses of Neomycin [0.5 %w/v], Polymyxin B (Sulphate) [10000 IU/ml], Prednisolone and Prednisone [0.5 %w/v] Eye Syrup/Suspension:

• Used for treating eye infections caused by bacteria, such as conjunctivitis or bacterial keratitis.
• Used to control and reduce inflammation in the eye, particularly in cases of allergic conjunctivitis or inflammatory eye conditions.
• Used for managing and alleviating eye inflammation and pain after eye surgery or eye injury.
• Used to prevent and treat eye infections and inflammation associated with corneal ulcers or abrasions.
• Used to relieve symptoms of eye allergies, including itching, redness, and swelling.
• Used for managing eye infections and promoting healing in cases of minor corneal injuries.
• Used to suppress the immune response and prevent rejection in corneal transplant surgeries.
• Used as an adjunct therapy to control inflammation and prevent secondary infections in various eye conditions.

In the case of an overdose of Neomycin [0.5% w/v], Polymyxin B (Sulphate) [10000 IU/ml], Prednisolone, and Prednisone [0.5% w/v] Eye Syrup/Suspension, the following symptoms may occur severe eye irritation, redness, and potential damage to the cornea. If ingested, it can lead to gastrointestinal issues, nausea, and potential systemic effects due to the corticosteroids. Immediate medical intervention is necessary, including rinsing the eyes with sterile water and seeking professional advice for further treatment.

In the case of a missed dose of Neomycin [0.5 %w/v], Polymyxin B (Sulphate) [10,000 IU/ml], Prednisolone and Prednisone [0.5 %w/v] Eye Syrup/Suspension, administer the medication as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for advice on how to get back on track with your medication regimen.

To administer the Neomycin 0.5% w/v, Polymyxin B (Sulphate) 10,000 IU/ml, and Prednisolone and Prednisone 0.5% w/v Eye Syrup/Suspension, gently shake the bottle, and use the provided dropper or a sterile dropper to instill the prescribed number of drops into the affected eye(s) as directed by your healthcare professional.

Following are the conditions/situations when Neomycin [0.5 %w/v], Polymyxin B (Sulphate) [10,000 IU/ml], Prednisolone and Prednisone [0.5 %w/v] Eye Syrup/Suspension should not be used:

• Do not use if you have a known allergy or hypersensitivity to any of the active ingredients (Neomycin, Polymyxin B, Prednisolone, or Prednisone) or any of the excipients in the eye syrup/suspension.
• Avoid using this medication if you have a history of viral, fungal, or mycobacterial infections in the eye(s).
• Not recommended for individuals with untreated bacterial eye infections.
• Should not be used in patients with a history of corneal ulcers or perforation.
• Contraindicated in individuals with herpes simplex keratitis (a type of eye infection caused by the herpes virus).
• Do not use if you have a history of ocular tuberculosis.
• Not suitable for patients with recent eye surgery, such as cataract extraction.

The side effects of Neomycin [0.5 %w/v], Polymyxin B (Sulphate) [10,000 IU/ml], Prednisolone and Prednisone [0.5 %w/v] Eye Syrup/Suspension may include:

• Eye irritation or redness
• Stinging or burning sensation in the eye
• Blurred vision
• Itching or swelling around the eye
• Increased eye pressure (glaucoma)
• Allergic reactions such as skin rash, itching, or hives
• Prolonged use may lead to fungal eye infections

Following are the precautions and warnings for Neomycin [0.5 %w/v], Polymyxin B (Sulphate) [10000 IU/ml], Prednisolone and Prednisone [0.5 %w/v] Eye Syrup/Suspension:

• Do not use this medication if you are allergic to any of its ingredients, including Neomycin, Polymyxin B, Prednisolone, or Prednisone.
• This medication is for external eye use only; do not swallow or inject.
• Avoid contact with eyes if you have a known history of hypersensitivity to any of the components.
• Do not wear contact lenses while using this medication; it may contain preservatives that can be absorbed by contact lenses.
• If you are using other eye medications, apply them at least 5-10 minutes before or after this medication to prevent dilution.
• Do not use for prolonged periods without medical supervision, as it may lead to increased eye pressure or other eye complications.
• Discontinue use and consult a doctor if you experience eye pain, changes in vision, or worsening of symptoms.
• Keep out of reach of children and pets.

Following are the drug interactions for Neomycin, Polymyxin B, Prednisolone, and Prednisone Eye Syrup/Suspension:

• Aminoglycosides (like Neomycin) and polymyxins (like Polymyxin B) can enhance the ototoxicity of certain medications, such as cisplatin and vancomycin.
• The bioavailability of corticosteroids (Prednisolone and Prednisone) may be increased by drugs that reduce metabolism, including macrolide antibiotics and protease inhibitors.
• Concomitant use of other immunosuppressants or corticosteroids can increase the risk of immunosuppression and infection.
• Live vaccines should be avoided during treatment due to potential reduced immune response.
• Anticoagulants like warfarin may have increased effects when used with corticosteroids, requiring close monitoring.
• Interactions with nonsteroidal anti-inflammatory drugs (NSAIDs) can increase the risk of gastrointestinal bleeding.
• Caution is advised with anti-diabetic medications as corticosteroids can increase blood glucose levels.

Following are the food interactions for Neomycin [0.5 %w/v], Polymyxin B (Sulphate) [10000 IU/ml], Prednisolone and Prednisone [0.5 %w/v] Eye Syrup/Suspension:

• This medication is for ophthalmic use only, so there are no direct food interactions as it is not ingested.
• Avoid consuming alcohol during the treatment period, as it can cause temporary blurring of vision and may reduce your ability to focus.
• Grapefruit juice should be consumed with caution as it may affect the absorption of certain ingredients, although this is less likely with eye drops.
• Avoid high-fat meals as they may increase the absorption of prednisolone and prednisone, potentially affecting their therapeutic effect.
• Avoid dairy products if you are lactose intolerant, as some eye drops may contain lactose.
• Certain foods with a high vitamin A content, like liver, should be consumed in moderation to avoid potential interactions with prednisolone.
• Always follow the dosage instructions provided by your healthcare professional, and ensure you inform them about any dietary concerns or restrictions you may have.
• The medication is administered topically to the eyes, so the impact of food interactions is minimal, but it's best to maintain a balanced diet for overall health.

Neomycin [0.5 %w/v], Polymyxin B (Sulphate) [10,000 IU/ml], Prednisolone and Prednisone [0.5 %w/v] Eye Syrup/Suspension should be stored in a cool, dry place, preferably at room temperature (between 20-25°C). Keep the syrup in its original container, tightly sealed, to maintain its integrity and prevent contamination. Avoid exposure to direct sunlight, heat, or moisture, as these factors can degrade the medication. Dispose of any unused or expired syrup responsibly; do not flush it into plumbing systems or discard it with regular waste. Consult a pharmacist or healthcare professional for guidance on proper disposal methods. Ensure that the medication is kept out of children's reach to prevent accidental consumption.

Following are the quick tips for Neomycin, Polymyxin B (Sulphate), Prednisolone and Prednisone Eye Syrup/Suspension:

• Wash your hands thoroughly before administering the eye drops or ointment to maintain hygiene.
• Follow the prescribed dosage and duration provided by your doctor for effective treatment.
• Gently pull down the lower eyelid and apply the medication inside the lower lid using the dropper or applicator.
• Close your eyes for a few minutes after application to allow the medicine to absorb.
• Avoid touching the tip of the dropper or tube to any surface to prevent contamination.
• Store the medication at room temperature, away from direct sunlight and moisture.
• Do not wear contact lenses while using this medication unless advised by your eye doctor.
• Inform your doctor if you have any eye infections, injuries, or allergies before using this medication.