Biostat (5/15mg/ml) 15ml Eye Drops

Boric Acid/Chloramphenicol eye drops have a dual mechanism of action. Boric acid acts as a mild antiseptic and buffering agent. It helps to maintain the pH of the eye drop solution and provides a soothing effect on the eyes. The primary role of boric acid is to support the antimicrobial activity of chloramphenicol and enhance its overall effectiveness. Chloramphenicol, on the other hand, is a broad-spectrum antibiotic that inhibits bacterial protein synthesis. It binds to the 50S ribosomal subunit of bacteria, preventing the formation of peptide bonds during protein synthesis. This disrupts bacterial cell growth and replication, effectively killing a wide range of bacteria responsible for various eye infections. By combining boric acid and chloramphenicol, the eye drops provide both antimicrobial and buffering properties, making them suitable for treating bacterial eye infections.

Antimicrobial, Anti-infective

Drop

The following are the uses of Boric Acid 0.05, Chloramphenicol [ 0.5 %w/v] Drop:

• Used for treating eye infections such as conjunctivitis
• Used as an antiseptic eye wash to cleanse and soothe irritated eyes
• Used for preventing eye infections after minor eye injuries or surgeries
• Used for reducing eye redness and swelling associated with bacterial infections
• Used for providing temporary relief from eye discomfort and itching
• Used for treating bacterial corneal ulcers and superficial infections
• Used for maintaining eye hygiene and preventing the spread of eye infections
• Used for its antimicrobial properties to inhibit the growth of bacteria in the eye

In the case of an overdose of Boric Acid 0.05, seek medical assistance promptly. Symptoms may include nausea, vomiting, and abdominal pain. For Chloramphenicol 0.5% w/v drops, overdose can lead to severe side effects like bone marrow suppression and gastrointestinal issues. If ingested, contact a healthcare professional immediately for guidance and treatment options.

In the case of a missed dose of Boric Acid 0.05, it is generally advised to apply the eye drops as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. However, if you miss a dose of Chloramphenicol 0.5% w/v eye drops, administer the missed dose as soon as possible, but if it's close to the time for your next dose, skip the missed dose and continue with your regular dosing regimen. Do not double the dose to make up for a missed one.

To use Boric Acid 0.05 and Chloramphenicol 0.5% w/v eye drops, gently tilt your head back, pull the lower eyelid down to create a pocket, and hold the dropper close to the eye. Squeeze one drop into the pocket, being careful not to touch the dropper tip to your eye or any other surface. Close your eye gently and apply light pressure to the tear duct for a few seconds to prevent the drop from draining out.

Following are the conditions or situations when Boric Acid 0.05, Chloramphenicol 0.5 %w/v eye drops should not be used:

• Must not be used if you are allergic to chloramphenicol or any other ingredients in the eye drops.
• Avoid using these eye drops if you have a viral or fungal infection in your eye(s).
• Do not use if you have a history of blood disorders or bone marrow depression.
• Not suitable for individuals with a known sensitivity to boric acid.
• Should not be used if you have a corneal ulcer or abrasion.
• Avoid using these drops if you have a history of Stevens-Johnson syndrome or toxic epidermal necrolysis.
• Contraindicated in individuals with a history of anaphylactic reactions to chloramphenicol.
• Do not use if you have a history of optic nerve damage.

The side effects of Boric Acid 0.05, Chloramphenicol [0.5 %w/v] Eye Drop may include:

• Eye irritation or redness
• Stinging or burning sensation in the eye
• Temporary blurred vision
• Watery eyes
• Sensitivity to light (photophobia)
• Allergic reactions, such as itching, swelling, or rash
• Dry eyes
• Increased eye discharge

Following are the precautions and warnings for Boric Acid 0.05, Chloramphenicol [0.5 %w/v] Drops:

• Do not use these eye drops if you are allergic to any of their ingredients, including boric acid or chloramphenicol.
• Avoid using the drops if you have a known sensitivity or allergy to other antibiotics from the same class as chloramphenicol.
• These drops are for external use only and should not be ingested or injected.
• Do not touch the dropper tip to any surface as it may contaminate the solution.
• Discontinue use and consult a doctor if you experience increased eye irritation, redness, or any other adverse effects.
• Do not use the drops if the solution has changed color or become cloudy, as this may indicate contamination.
• Keep out of reach of children and pets. Store in a cool, dry place, away from direct sunlight.

Following are the drug interactions for Boric Acid 0.05, Chloramphenicol 0.5%w/v Drops:

• Chloramphenicol may reduce the effectiveness of live attenuated virus vaccines, such as measles, mumps, and rubella (MMR) or varicella vaccines. Vaccination should be considered before starting treatment.
• Concomitant use with other antibiotics, especially aminoglycosides, may enhance the antibacterial effect but also increase the risk of ototoxicity and nephrotoxicity.
• Chloramphenicol can inhibit the metabolism of drugs metabolized by the liver, including warfarin, phenytoin, and cyclosporine, leading to increased levels of these medications.
• It may decrease the effectiveness of oral contraceptives, potentially reducing their contraceptive protection.
• Alcohol consumption should be avoided as it may increase the risk of side effects and slow down the healing process.
• Boric acid can be toxic when ingested orally, so caution is advised when using with other medications that may affect its absorption or metabolism.
• The use of other topical eye medications should be carefully monitored, as they may dilute or interact with the chloramphenicol eye drops.

Following are the food interactions for Boric Acid 0.05, Chloramphenicol [0.5 %w/v] Drop:

• Avoid consuming alcohol during the treatment period as it may increase the risk of side effects and affect the overall healing process.
• Grapefruit and grapefruit juice should be avoided as they can interfere with the medication's metabolism, potentially leading to increased drug levels in the body.
• Dairy products like milk, cheese, and yogurt may decrease the absorption of Chloramphenicol, so it's best to separate them by a few hours.
• High-fat meals may slow down the absorption of the medication, so it is advisable to take the medication on an empty stomach or as directed by your doctor.
• Avoid caffeine-rich foods and beverages like coffee, tea, and chocolate, as they may enhance the effects of Chloramphenicol and increase the risk of side effects.
• Certain foods rich in vitamin K, such as leafy green vegetables, broccoli, and liver, may interact with Chloramphenicol and affect blood clotting. Consult your doctor for dietary advice.
• Avoid sugary foods and beverages, as they may promote bacterial growth and reduce the effectiveness of the medication.
• Follow a balanced diet as recommended by your healthcare provider to support overall healing and recovery during the treatment period.

Boric Acid 0.05 and Chloramphenicol [0.5 %w/v] Drops should be stored in a secure and designated area, ensuring they are out of reach of children and pets. Keep the drops in a cool, dry place, preferably at room temperature, and away from direct sunlight, heat, or moisture. Do not freeze the solution. It is crucial to store the drops in their original container, tightly sealed, to maintain their integrity and prevent contamination. Always check the expiration date, and do not use the drops if they have passed this date. For disposal, do not pour the drops down the drain or flush them; instead, follow local guidelines for pharmaceutical waste disposal or consult a healthcare professional for advice on safe disposal methods.

Following are the quick tips for this Drops:

• Apply as directed by your healthcare provider, ensuring the affected area is clean and dry.
• Wash your hands before and after application to maintain hygiene.
• Use a sterile applicator or follow the prescribed method for administration.
• Avoid touching the tip of the applicator to prevent contamination.
• Do not share this medication with others to prevent the spread of infection.
• Store it at room temperature, away from moisture and light.
• Wash your hands thoroughly before applying the eye drops.
• Tilt your head back, and gently pull down your lower eyelid to create a pocket.
• Hold the dropper above the eye and squeeze the prescribed number of drops into the pocket.
• Close your eyes gently and roll your eyeball to distribute the medication evenly.
• Avoid touching the dropper tip to your eye or any surface to prevent contamination.
• If using other eye medications, wait at least 5 minutes before applying the next one.
• Store the eye drops at room temperature, away from heat and direct light.