BISEKO 50ML INJ

The mechanism of action of Human Plasma Proteins 50g injection is primarily attributed to its ability to replenish deficient plasma proteins in the body. This injection contains a diverse array of proteins found in human plasma, including albumin, immunoglobulins, clotting factors, and various other proteins. When administered, these proteins work synergistically to restore and maintain the physiological functions of the blood. Albumin helps regulate osmotic pressure and transports various substances, while immunoglobulins play a crucial role in the immune system by neutralizing pathogens and toxins. Additionally, clotting factors are essential for proper blood coagulation, aiding in the body's natural process of forming clots to prevent excessive bleeding. The injection's efficacy lies in its comprehensive protein composition, which mimics the natural balance of plasma proteins, thereby supporting vital physiological processes.

Human Plasma Proteins 50g

Albumin

injection

The following are the uses of Human Plasma Proteins 50g injection:

• Used for treating severe burns and injuries, promoting tissue healing.
• Used for managing blood clotting disorders, aiding in coagulation.
• Used in emergency trauma care to stabilize patients.
• Used for supporting liver function and treating liver diseases.
• Used for immune system disorders, providing essential proteins.
• Used during surgeries to replace lost blood volume.
• Used for wound management, enhancing healing processes.

In the case of an overdose of Human Plasma Proteins 50g injection, individuals may experience a range of symptoms. These can include increased heart rate, elevated blood pressure, and potential fluid overload. Respiratory distress and swelling at the injection site are also possible. It is important to monitor for these signs and seek medical assistance if any adverse effects are observed, as prompt treatment can help mitigate potential complications.

In the case of a missed dose of Human Plasma Proteins 50g injection, it is important to administer the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed, as they may recommend adjusting the dosage or provide specific instructions for your situation.

To administer the Human Plasma Proteins 50g injection, clean the injection site with an alcohol swab, insert the needle at a 90-degree angle, and slowly inject the prescribed dose subcutaneously, ensuring the entire content is delivered before withdrawing the needle.

Here are the situations or conditions when Human Plasma Proteins 50g injection should not be administered:

• Not recommended for individuals with a history of severe allergic reactions to plasma products or any components of the injection.
• Contraindicated in patients with a known hypersensitivity to human plasma or any of its proteins.
• Should not be used if the patient has a history of anaphylactic or severe systemic reactions to immunoglobulin A (IgA).
• Not suitable for individuals with thrombotic disorders or a history of thromboembolic events.
• Avoid using in patients with severe renal impairment or end-stage renal disease.
• Not recommended for individuals with severe cardiovascular disease or hypertension that is not well-controlled.
• Contraindicated in patients with a history of hemodynamic instability or shock.
• Should not be administered to patients with severe liver disease or impaired liver function.
• Avoid using in individuals with a known deficiency of Factor V or Factor XI, as it may worsen the bleeding risk.

The side effects of Human Plasma Proteins 50g injection may include:

• Allergic reactions, such as hives, itching, or rash.
• Fever or chills.
• Rapid or pounding heartbeat.
• Shortness of breath or difficulty breathing.
• Swelling, especially in the face, hands, or feet.
• Chest pain or discomfort.
• Nausea and vomiting.
• Unusual tiredness or weakness.

Following are the precautions and warnings for Human Plasma Proteins 50g injection:

• Not recommended for individuals with a history of hypersensitivity or severe allergic reactions to human plasma proteins or any component of the injection.
• Patients with a history of cardiovascular disease, kidney disorders, or blood clotting disorders should use with caution and under medical supervision.
• May cause fluid overload in patients with heart or kidney conditions, so dosage should be adjusted accordingly.
• Elderly patients may be more susceptible to adverse effects, and close monitoring is advised.
• Avoid if you have a history of hemochromatosis or iron overload as it may exacerbate these conditions.
• Discontinue use and seek medical attention if signs of anaphylaxis or severe allergic reactions occur.
• This injection should be administered by trained medical professionals in a controlled medical setting.
• Patients with liver disease should use with caution as it may affect protein metabolism.

Following are the drug interactions for Human Plasma Proteins 50g injection:

• Human Plasma Proteins may interfere with the effectiveness of live attenuated vaccines, such as measles, mumps, and rubella vaccines, due to the presence of antibodies in the plasma. It's recommended to complete live vaccine series before administration.
• Concomitant use with other plasma-derived products can lead to volume overload, especially in patients with cardiac or renal impairment.
• Co-administration with drugs affecting blood coagulation, such as warfarin, may require adjustment of anticoagulant dosage to maintain the desired level of anticoagulation.
• The injection may impact the metabolism of drugs relying on hepatic clearance, potentially requiring dosage adjustments.
• Use with caution in patients on diuretics, as rapid volume expansion may affect fluid balance.
• May influence the efficacy of immunosuppressants in transplant patients, necessitating close monitoring.
• Human Plasma Proteins may interact with drugs that are highly protein-bound, potentially altering their distribution and effectiveness.

Following are the food interactions for Human Plasma Proteins 50g injection:

• Avoid consuming high-protein foods or supplements, as they can alter the protein balance and potentially affect the effectiveness of the injection.
• Ensure adequate fluid intake, as proper hydration is crucial for maintaining blood volume and preventing potential side effects.
• Salt intake should be monitored, as the injection may contain sodium, and excessive salt consumption can lead to fluid retention.
• Avoid grapefruit and grapefruit juice, as they can affect the metabolism of some medications and potentially interact with the injection's components.
• Limit alcohol consumption, as it can interfere with the healing process and may increase the risk of bleeding and infection at the injection site.
• Avoid caffeine-rich foods and beverages, as they can impact blood flow and potentially interfere with the injection's intended effects.
• Consult your healthcare provider for specific dietary recommendations, especially if you have pre-existing dietary restrictions or medical conditions.
• No significant interactions have been reported with specific foods, but maintaining a balanced diet is generally advised.

Storage and disposal of Human Plasma Proteins 50g injection require careful attention. Store the injection in a controlled room temperature environment, between 20-25°C (68-77°F), away from excessive heat, moisture, and direct sunlight. Protect it from freezing and avoid exposure to extreme temperatures. Ensure the injection is kept in its original packaging, tightly sealed, to maintain sterility. Do not use if the solution appears discolored or contains particles. Dispose of any unused or expired medication responsibly; do not pour it down the drain or flush it into the sewage system. Contact your healthcare provider or pharmacist for guidance on proper disposal methods to ensure environmental safety. Keep this medication out of children's reach to prevent accidental ingestion.

Following are the quick tips for Human Plasma Proteins 50g injection:

• Administer the injection under medical supervision for safe and effective use.
• Ensure the injection is stored at the appropriate temperature as directed by the manufacturer.
• Verify the expiry date before use and do not use if expired.
• Follow proper aseptic techniques during administration to prevent infection.
• Use a sterile syringe and needle for injection, and dispose of them safely after use.
• Rotate injection sites to minimize tissue irritation.
• Inform your healthcare provider if you experience any unusual symptoms after the injection.