BLISSCOLIC SYP

Dicyclomine primarily exerts its therapeutic effects through its action as an anticholinergic agent. It competitively blocks acetylcholine from binding to muscarinic receptors, particularly M1 and M3 subtypes, which are predominantly found in the smooth muscles of the gastrointestinal tract, biliary tract, and urinary bladder. By inhibiting the stimulation of these receptors, dicyclomine reduces gastrointestinal motility, decreases intestinal secretions, and relaxes the smooth muscles. This mechanism leads to a reduction in abdominal cramps, lessens intestinal spasms, and alleviates symptoms associated with irritable bowel syndrome and other gastrointestinal disorders.

Anticholinergic

Suspension

The following are the uses of Dicyclomine Syrup/Suspension:

• Used for relieving abdominal pain and cramps caused by irritable bowel syndrome (IBS) and other digestive disorders.
• Used for reducing muscle spasms in the intestines, aiding in digestive comfort.
• Used for managing symptoms of functional gastrointestinal disorders, such as bloating and discomfort.
• Used for providing short-term relief from intestinal hyperactivity and associated symptoms.
• Used for restoring normal bowel function and reducing excessive intestinal contractions.
• Used for treating symptoms of intestinal colic in infants and children.
• Used for controlling involuntary bowel movements in certain conditions.

In the case of an overdose of Dicyclomine Syrup/Suspension, individuals may experience severe gastrointestinal symptoms such as nausea, vomiting, abdominal pain, and diarrhea. Central nervous system effects like drowsiness, confusion, and blurred vision can also occur. Prompt medical intervention is necessary, as overdoses may lead to respiratory depression, hypotension, and in severe cases, seizures. Medical professionals should be informed about the amount ingested, and treatment may include gastric lavage, supportive care, and monitoring of vital signs.

In the case of a missed dose of Dicyclomine Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen. It is advisable to set reminders or use a pill organizer to help you stay on track with your medication routine.

To take Dicyclomine Syrup/Suspension, shake the bottle well, then use a measuring device like a dosing spoon or syringe to measure the prescribed amount, and take it orally, following the dosage instructions provided by your healthcare professional, typically once a day with or without food, ensuring you adhere to the recommended dosage guidelines.

Following are the conditions/situations when Dicyclomine Syrup/Suspension should not be used:

• Do not use in patients with a known allergy or hypersensitivity to Dicyclomine or other similar anticholinergic drugs.
• Contraindicated in patients with gastrointestinal conditions like ulcerative colitis, intestinal obstruction, or reflux esophagitis.
• Not suitable for individuals with a history of liver or kidney disease.
• Should not be used in patients with a history of urinary retention or an enlarged prostate.
• Contraindicated in individuals with myasthenia gravis due to potential worsening of symptoms.
• Not recommended for infants or children under 6 months of age.
• Should not be used in patients with a history of narrow-angle glaucoma.
• Avoid in patients with a history of heart disease or tachycardia.

The side effects of Dicyclomine Syrup/Suspension may include:

• Dry mouth
• Blurred vision
• Dizziness or drowsiness
• Constipation
• Nausea or vomiting
• Difficulty urinating
• Skin rash or itching
• Confusion, especially in elderly patients

Following are the precautions and warnings for Dicyclomine Syrup/Suspension:

• Do not use in patients with hypersensitivity or known allergies to Dicyclomine or related compounds.
• Not recommended for children under 6 months of age.
• Use with caution in elderly patients as they may be more susceptible to side effects.
• Dicyclomine can cause drowsiness and blurred vision, so patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• It should be used with caution in patients with gastrointestinal conditions like ulcerative colitis, as it may worsen these conditions.
• Patients with kidney or liver disease should use this medication with caution and under medical supervision.
• If symptoms persist or worsen, or if you experience severe side effects like difficulty breathing, seek immediate medical attention and discontinue use.
• Consult a healthcare professional before use if you are pregnant, planning to become pregnant, or breastfeeding.

Following are the drug interactions for Dicyclomine Syrup/Suspension:

• It may cause increased sedation when taken with other drugs that also cause drowsiness, such as antihistamines, opioids, or certain antidepressants.
• Dicyclomine can interact with anticholinesterase agents, potentially resulting in increased anticholinergic effects and reduced therapeutic efficacy of the anticholinesterase medication.
• When combined with potassium-depleting diuretics, it may further lower potassium levels in the body.
• This medication can interact with antimuscarinic drugs, leading to increased antimuscarinic effects and potential side effects.
• Dicyclomine may reduce the absorption of certain antibiotics, affecting their effectiveness.
• Caution is advised when using with drugs that prolong QT interval, as it may increase the risk of cardiac arrhythmias.
• It may decrease the effectiveness of gastrointestinal prokinetic agents.

Following are the food interactions to consider with Dicyclomine Syrup/Suspension:

• Alcohol consumption should be avoided as it can increase the sedative effects, leading to enhanced drowsiness and dizziness.
• Grapefruit and its juice are to be avoided as they can increase Dicyclomine levels in the blood, potentially causing more side effects.
• Caffeine intake should be monitored as it can exacerbate certain side effects, especially nervousness and insomnia.
• Foods high in fat can slow down the absorption of Dicyclomine, potentially reducing its effectiveness.
• Dairy products may interact with Dicyclomine, so it's advisable to separate them by a few hours to ensure optimal absorption.
• Spicy foods may aggravate gastrointestinal issues, so it's best to minimize their consumption while on Dicyclomine.
• A balanced diet is essential to support overall health and can aid in managing the side effects of Dicyclomine.
• Always follow the dosage instructions provided by your healthcare professional for the best results.

Dicyclomine Syrup/Suspension should be stored with care, preferably in a cool and dry place, maintaining a temperature below 25°C. Protect it from direct sunlight, heat, and moisture to ensure its effectiveness. Keep the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. It is crucial to dispose of any unused or expired Dicyclomine Syrup/Suspension responsibly; do not flush it down the toilet or pour it into drains. Consult your pharmacist or local waste disposal company for guidance on proper disposal methods. Always keep the medication out of children's reach to prevent accidental consumption. Regularly check the expiration date, and do not use the syrup if it has expired, as its potency and safety may be compromised.

Following are the quick tips for Dicyclomine Syrup/Suspension:

• Consult a doctor for the correct dosage and usage instructions for children.
• Store the medication in a cool, dry place, away from direct sunlight and moisture.
• Ensure the medication is prescribed for your specific condition and is not shared with others.
• Do not increase or decrease the dosage without medical advice.
• Avoid driving or operating heavy machinery until you know how the medication affects you.
• Inform your doctor about all medications you are taking to prevent potential drug interactions.
• If symptoms persist or worsen, seek medical attention promptly.