Bon D (400IU/500mg) 10 Tablets

Cholecalciferol, also known as vitamin D3, has a specific mechanism of action in the body. It is a precursor to the active form of vitamin D, calcitriol. When Cholecalciferol is ingested, it is first absorbed in the small intestine and then transported to the liver, where it undergoes hydroxylation to form 25-hydroxyvitamin D (calcidiol). This metabolite is further hydroxylated in the kidneys to produce the biologically active form, 1,25-dihydroxyvitamin D (calcitriol). Calcitriol binds to the vitamin D receptor (VDR) in various target cells, primarily in the intestine, bones, and kidneys. This binding activates the receptor, which then acts as a transcription factor, regulating gene expression. The primary effect of calcitriol is to increase intestinal absorption of calcium and phosphorus, promoting bone mineralization. It also enhances renal tubular reabsorption of calcium, further contributing to calcium homeostasis. Additionally, Cholecalciferol has been shown to have immunomodulatory effects and plays a role in various cellular processes, including cell proliferation and differentiation.

Cholecalciferol 400iu

Vitamin D3 supplement

Tablet

The following are the uses of Cholecalciferol 400iu Tablet:

• Used for treating and preventing Vitamin D deficiency.
• Used to maintain healthy bones and teeth by regulating calcium absorption.
• Used to support immune system health and reduce the risk of autoimmune diseases.
• Used for managing conditions like rickets and osteomalacia.
• Used to improve muscle strength and overall physical performance.
• Used for individuals with limited sun exposure or malabsorption issues.
• Used as a supplement during pregnancy and breastfeeding to ensure adequate Vitamin D levels.
• Used to reduce the risk of fractures and falls in older adults.

In the case of an overdose of Cholecalciferol 400iu Tablets, symptoms may include nausea, vomiting, constipation, loss of appetite, weakness, and increased thirst and urination. Prolonged excessive intake can lead to more severe symptoms such as kidney damage, high blood pressure, and irregular heart rhythms. If an overdose is suspected, it is vital to seek medical advice promptly, as treatment may involve managing symptoms and providing supportive care to prevent further complications. Immediate medical intervention can help mitigate potential health risks.

In the case of a missed dose of Cholecalciferol 400iu Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare professional for advice on how to proceed, as they may recommend adjusting your dosage or provide specific instructions to ensure you receive the appropriate amount of medication.

To take Cholecalciferol 400iu Tablet, place the tablet on your tongue and swallow it with a glass of water, preferably with a meal or as directed by your healthcare professional, ensuring you follow the prescribed dosage instructions.

Here are the conditions and situations when Cholecalciferol 400iu Tablet should not be taken:

• Avoid if you have a known allergy to vitamin D or any of the excipients in the tablet.
• Do not take if you have high levels of calcium in your blood (hypercalcemia) or are experiencing symptoms of hypercalcemia.
• Contraindicated in individuals with kidney stones or conditions that cause high calcium excretion in the urine (hypercalciuria).
• Not suitable for those with conditions causing calcium buildup in tissues (metastatic calcification), such as in the lungs or blood vessels.
• Avoid using this tablet if you have uncontrolled or untreated hyperparathyroidism.
• Do not take this supplement if you are taking other vitamin D supplements or medications that increase vitamin D levels.
• Avoid using Cholecalciferol tablets if you have a condition that impairs your body's ability to absorb dietary fats, as this can affect vitamin D absorption.

The side effects of Cholecalciferol 400iu Tablet may include:

• Nausea and vomiting
• Constipation or diarrhea
• Loss of appetite
• Dry mouth
• Metallic taste in the mouth
• Increased thirst
• Muscle or bone pain
• Fatigue and weakness

Following are the precautions and warnings for Cholecalciferol 400iu Tablet:

• Avoid excessive dosage, as it may lead to hypervitaminosis D, causing symptoms like nausea, vomiting, and potential kidney damage.
• Regular monitoring of calcium and phosphate levels is essential during prolonged treatment.
• Patients with a history of kidney stones or hypercalcemia should exercise caution and consult a healthcare professional before use.
• Not recommended for individuals with hypervitaminosis D or conditions causing excessive calcium absorption.
• Should be used with caution in patients with a history of kidney disease or impaired kidney function.
• Patients with sarcoidosis should avoid this medication as it can lead to elevated calcium levels.
• Pregnant and breastfeeding women should consult a healthcare provider before taking this medication, as it may affect fetal or infant development.
• Keep out of reach of children to prevent accidental overdose.

Following are the drug interactions for Cholecalciferol 400iu Tablet:

• Thiazide diuretics may decrease the excretion of vitamin D, potentially leading to hypercalcemia.
• Cholestyramine can reduce the absorption of vitamin D, resulting in decreased effectiveness.
• Anticonvulsants like phenobarbital and phenytoin may induce metabolism, reducing vitamin D levels.
• Corticosteroids can decrease calcium absorption, and concurrent use with vitamin D may require higher doses.
• Orlistat can impair the absorption of fat-soluble vitamins, including vitamin D.
• Aluminum-containing antacids can decrease vitamin D absorption when taken simultaneously.
• Calcium channel blockers may increase the risk of hypercalcemia when used with vitamin D.

Following are the food interactions for Cholecalciferol 400iu Tablet:

• Avoid excessive consumption of Vitamin D-rich foods like fatty fish, egg yolks, and fortified dairy products while taking this medication, as it may lead to Vitamin D toxicity.
• Maintain a balanced diet with adequate calcium and phosphorus, as these minerals work in synergy with Vitamin D for optimal bone health.
• Avoid high-fiber foods and mineral oil as they can interfere with the absorption of Vitamin D.
• Consume foods rich in healthy fats like avocado, nuts, and olive oil to enhance the absorption of this fat-soluble vitamin.
• Limit caffeine intake as it may interfere with Vitamin D metabolism and reduce its effectiveness.
• Avoid excessive alcohol consumption as it can impair Vitamin D metabolism and reduce calcium absorption.
• Consider consulting a dietician to create a personalized diet plan to support your Vitamin D therapy, especially if you have specific dietary restrictions or medical conditions.
• Follow your healthcare provider's advice regarding any specific dietary recommendations during your treatment.

Cholecalciferol 400iu Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. It is crucial to keep the tablets in their original packaging, tightly sealed, to maintain their integrity. Avoid exposing the medication to heat or cold extremes, as it can affect its potency. When disposing of unused or expired tablets, do not flush them down the toilet or discard them into the environment. Contact your pharmacist or local waste management authority for instructions on safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Cholecalciferol 400iu Tablet:

• Consult your doctor to determine the correct dosage and duration for your specific needs.
• Take the tablet as directed, typically once daily or as prescribed.
• Swallow the tablet whole with a glass of water; do not crush or chew.
• Take the tablet with a meal to enhance absorption.
• Maintain a consistent schedule to ensure stable vitamin D levels.
• Do not take more than the prescribed dose; overdose may lead to serious side effects.
• Store the medication in a cool, dry place, away from direct sunlight.
• Inform your doctor about all medications you are taking to avoid potential interactions.