Bonedol (0.5ug ) 10 Tablets

Alfacalcidol (0.5μg) is an artificial active vitamin D3 analog that acts as a selective activator of the vitamin D receptor (VDR). This receptor is found in several tissues, including the kidney, pancreas, intestine, and parathyroid glands. It maintains calcium and phosphate homeostasis and promotes bone health. It is used to treat renal osteodystrophy, osteoporosis, and hypoparathyroidism. When taken orally, alfacalcidol is metabolized in the liver to calcitriol, the active form of vitamin D3. Calcitriol interacts with the vitamin D receptor (VDR) in the nucleus of target cells, such as osteoblasts and renal tubular cells. This interaction results in the transcription and subsequent synthesis of proteins necessary for calcium and phosphate homeostasis, such as 24-hydroxylase and alkaline phosphatase. Additionally, alfacalcidol also inhibits the secretion of parathyroid hormone (PTH) from the parathyroid glands, which helps to reduce bone resorption and restore healthy calcium and phosphate levels.

Alfacalcidol 0.5mcg

D3 Vitamins

Tablet

Alfacalcidol is utilized for the following therapeutic indications:

• Manages vitamin D deficiency and insufficiency
• Helps regulate calcium and phosphate levels in the body
• Supports bone health in patients with renal osteodystrophy
• Assists in the treatment of osteoporosis

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For adults taking immunosuppressants for mild to moderate hypophosphatemia- Start with 1 tablet of Alfacalcidol 0.5μg per day.
• For treating vitamin D dependent rickets and kidney hemodialysis- Start with 1-2 tablets of Alfacalcidol 0.5μg per day.
• For children- Doses are based on weight and medical condition, so follow the doctor's instructions.

Alfacalcidol is a vitamin D derivative used to treat calcium and bone metabolism disorders. In the case of an Alfacalcidol overdose, it is important to seek immediate medical attention. Be sure to have the medication packaging accessible to share with medical personnel to ensure proper treatment. It is recommended to induce vomiting and wash out the overdose from the stomach to reduce the amount of the drug absorbed into the bloodstream and minimize potential complications. Despite the amount of medication consumed, it is important to seek medical attention due to the risk of serious complications from vitamin D toxicity. This covers some basic details regarding an Alfacalcidol overdose. If you'd like further information, additional details, or any other questions, feel free to ask!

If you miss a dose of Alfacalcidol 0.5μg, take the missed dose as soon as you can, but if it's almost time for your next scheduled dose, skip the missed dose and stick to your regular dosing schedule. It's important to not double the dose.To avoid missing a dose, you can set an alarm or a reminder and space out your doses accordingly. This will help you to adhere to the schedule outlined by your healthcare provider, which will ensure the best possible results and avoidance of any unwanted symptoms associated with low calcium levels.

Alfacalcidol is a medication used to treat patients presenting with hypocalcemia and chronic kidney disease. The dosage varies between individuals depending on age, weight, and condition severity, so it is important to follow the personalized instructions given by a medical professional. Taking Alfacalcidol with or after food helps to avoid an upset stomach and it should be taken at regular intervals, unless it is closer to the next scheduled dose, in which case it is best to just wait and take the next dose as normal. Never take two doses at once to make up for a missed dose. It is important to avoid alcohol while taking Alfacalcidol, as well as any medications or foods that inhibit phosphorous binding agents, as alcohol consumption can increase the risk of kidney stones. Side effects including leg cramps, nausea, vomiting, headaches, and bone pain are possible but rare. However, dizziness and nausea are common side effects that may dissipate over time. Whilst taking Alfacalcidol long-term, it is crucial to have regular check-ins with a doctor to monitor any changes in your body and kidney function, as well as updating them on any new medications or allergies. Ensure you read the individual patient information leaflet before starting Alfacalcidol, and consult with a doctor for specific treatment instructions.

Discerning instances where this medication may not be appropriate:

• You have recently undergone parathyroid surgery • Alfacalcidol 0.5μg is not recommended for people who have had surgery to remove the parathyroid gland or glands.
• You have high levels of calcium in your blood • Already high blood calcium levels mean you could experience further increases through use of Alfacalcidol 0.5μg.
• You have a sensitivity to Alfacalcidol or similar medications • If you have had allergic reactions or side effects from Alfacalcidol 0.5μg or other medications in the same class, you should not take this medication.
• You have a kidney injury or impaired kidney function • Alfacalcidol 0.5μg is excreted by the kidneys, so if your kidney function is impaired, there is a risk of excess calcium in the blood.
• You are taking other medications that interact with Alfacalcidol • Interaction with other medications can affect effectiveness or increase the risk of side effects.

Unraveling the side effects lurking behind this medications are as follows:

• Strengthens and increases bone growth in various body areas.
• Issues may arise if it occurs in abnormal proportions or rates.
• May cause the jawbone to enlarge, leading to pain, difficulty chewing, and misaligned teeth.
• Lack of Vitamin D

• Alfacalcidol is a synthetic vitamin D derivative.
• Can develop vitamin D2 deficiency if taken in excess and do not get enough vitamin D2 from natural sources.
• May result in symptoms such as weakness, muscle aches, and general pain.
• Potential Side Effects

• Nausea, vomiting, and diarrhea may be indicative of an allergy to Alfacalcidole or conflict with other drugs you are taking.
• Headaches and skin reactions, such as itching, rash, and dry skin due to Alfacalcidol administration.
• High Levels of Calcium in Blood

• One of the most severe complications is hypercalcemia, which is the presence of excessive calcium levels in the blood.
• Can lead to nausea, vomiting, frequent urination, and confusion.
• In extreme cases, it may lead to coma and death.

Alfacalcidol is a synthetic vitamin D derivative that treats low blood calcium and phosphate levels. It is usually taken as tablets or capsules, with a daily dosage of 0.5 to 1.5 micrograms. Ensure you follow the instructions on the medication label or as directed by your healthcare provider. Generally, it should be kept in its original container, tightly closed and stored in a cool, dry place away from direct heat or light. Avoid storing it in the bathroom as this environment can cause the medication to degrade faster. Keep it out of reach of children and pets and follow the expiration date as well. If you have any questions or concerns about storing Alfacalcidol 0.5μg, it is best to consult with your pharmacist or healthcare provider for more personalized guidance.