Bronkal (5mg/ml) 20ml Respirator Solution

Salbutamol Respiratory Solution, also known as albuterol, is a short-acting beta-2 agonist that exerts its effects by binding to beta-2 adrenergic receptors in the lungs. Upon binding, it activates the receptor, leading to the relaxation of smooth muscles surrounding the airways. This mechanism is primarily responsible for the bronchodilatory effect of salbutamol. Specifically, the activation of beta-2 receptors stimulates the production of cyclic adenosine monophosphate (cAMP) through the activation of adenylate cyclase. Elevated cAMP levels then activate protein kinase A, which ultimately inhibits the phosphorylation of myosin light chains, resulting in smooth muscle relaxation and improved airflow to the lungs. This targeted action makes salbutamol a valuable medication for the rapid relief of bronchoconstriction associated with conditions like asthma and chronic obstructive pulmonary disease (COPD).

Bronchodilator

solution

The following are the uses of Salbutamol Respirator Solution:

• Used for relieving symptoms of asthma and chronic obstructive pulmonary disease (COPD).
• Used for preventing asthma symptoms, especially during exercise or exposure to allergens.
• Used for treating bronchospasms, helping to relax and open the airways.
• Used for managing shortness of breath and wheezing in respiratory conditions.
• Used for quick relief of sudden asthma attacks or COPD exacerbations.
• Used for maintaining control of asthma and reducing the frequency of symptoms.
• Used for improving lung function and overall breathing capacity.

In the case of an overdose of Salbutamol Respiratory Solution, several symptoms may occur, including rapid heart rate, tremors, headache, and muscle cramps. If a person experiences these symptoms after taking an excessive amount of the solution, it is crucial to seek medical advice promptly. Treatment for overdose may involve monitoring vital signs, administering intravenous fluids, and providing supportive care to manage symptoms until the effects of the medication wear off. Prompt action can help prevent severe complications.

In the case of a missed dose of Salbutamol Respirator Solution, it is important to administer the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a medication tracker to help you stay on track with your treatment plan.

To use the Salbutamol Respirator Solution, twist the inhaler's base to load the dose, then breathe out, put the mouthpiece to your lips, and breathe in deeply while pressing down on the inhaler to release the medication.

Following are the conditions when Salbutamol Respirator Solution should not be used:

• Should not be used if you have a severe allergy to Salbutamol or other similar bronchodilators.
• Not indicated for patients with a history of heart problems, such as rapid or irregular heartbeat, severe heart disease, or recent heart attack.
• Contraindicated in individuals with severe or uncontrolled high blood pressure.
• Avoid using if you have experienced severe adverse reactions to sympathomimetic drugs in the past.
• Should not be used if you are currently taking medications for depression known as monoamine oxidase inhibitors (MAOIs).
• Not recommended for patients with diabetes, as it may mask the symptoms of low blood sugar.
• Do not use if you have a seizure disorder, as it may lower the seizure threshold.

The side effects of Salbutamol Respirator Solution may include:

• Tremors or shaking, especially in the hands
• Rapid heartbeat (tachycardia)
• Headache
• Dizziness
• Nervousness or anxiety
• Muscle cramps or spasms
• Dry mouth or throat irritation
• Nausea or vomiting

Following are the precautions and warnings:

• Salbutamol Respirator Solution should be used with caution in patients with heart problems, including irregular heartbeat, rapid heart rate, or pre-existing heart disease. It may cause increased heart rate and blood pressure.
• Patients with diabetes should monitor their blood sugar levels regularly as this medication can affect blood sugar control.
• Individuals with thyroid problems should use it with caution as it may worsen thyroid-related symptoms.
• It is important to inform your doctor if you have a history of seizures or epilepsy before using this medication.
• Avoid excessive use of Salbutamol, as it may lead to paradoxical bronchospasm, causing breathing difficulties.
• Patients should seek immediate medical attention if they experience chest pain, rapid heartbeat, or severe allergic reactions after using this solution.
• This medication is generally not recommended for individuals with a known allergy to salbutamol or related medications.
• Pregnant and breastfeeding women should consult their healthcare provider to weigh the benefits and risks before using Salbutamol Respirator Solution.

Following are the drug interactions for Salbutamol Respirator Solution:

• Beta-blockers, such as propranolol, can counteract the effects of salbutamol, leading to reduced bronchodilation.
• Xanthine derivatives (e.g., theophylline) may enhance the stimulatory effect of salbutamol on the cardiovascular system.
• Diuretics, especially potassium-depleting types, can cause hypokalemia, which may be exacerbated by salbutamol.
• Antihypertensives, Salbutamol may decrease the effectiveness of blood pressure-lowering medications.
• Tricyclic antidepressants and monoamine oxidase inhibitors can potentiate the cardiovascular effects of salbutamol.
• Salbutamol may interact with other sympathomimetic agents, increasing the risk of cardiovascular side effects.
• Concomitant use with digoxin may increase the risk of arrhythmias.
• Antifungal medications like ketoconazole can increase salbutamol levels, potentially leading to exaggerated pharmacological effects.

Following are the food interactions for Salbutamol Respirator Solution:

• Avoid consuming large amounts of foods or beverages containing caffeine, such as coffee, tea, or energy drinks, as it may increase the stimulant effects of Salbutamol.
• Grapefruit juice should be consumed with caution as it can potentially affect the metabolism of the medication, leading to increased levels in the body.
• Avoid excessive consumption of chocolate, as it contains a small amount of caffeine and may interact with the medication's stimulant properties.
• Alcohol may not directly interact with Salbutamol, but it's advisable to limit alcohol intake as it can affect breathing and may increase the risk of side effects.
• Dairy products like milk and cheese do not typically interact with Salbutamol, but if you have lactose intolerance or milk protein allergy, consult your doctor.
• Avoid high-potassium foods like bananas, oranges, and spinach if you have a potassium-related condition, as Salbutamol can potentially affect potassium levels.
• No specific restrictions on spicy foods, but if you have acid reflux or gastrointestinal issues, it's best to monitor your tolerance.
• Always stay hydrated, and drink plenty of water while using Salbutamol to maintain respiratory health.

Salbutamol Respirator Solution should be stored with care to maintain its effectiveness and safety. Keep it in a cool and dry place, preferably at room temperature, ensuring it's not exposed to direct sunlight or extreme temperatures. Store it in its original container, tightly sealed, to prevent contamination. It's crucial not to store it in bathrooms or near heat sources like radiators or stoves, as this can degrade the medication. Dispose of any unused or expired solution responsibly; do not flush it or pour it down the drain. Consult your pharmacist or healthcare provider for appropriate disposal methods to protect the environment. Lastly, always keep medications out of children's reach to prevent accidental ingestion.

Following are the quick tips for Salbutamol Respirator Solution:

• Before use, ensure the solution is clear and free from particles.
• Administer the prescribed dose via inhalation as directed by your doctor or pharmacist.
• Inhale slowly and deeply to ensure proper delivery of the medication.
• Rinse your mouth with water after each inhalation to prevent dryness.
• Keep the solution in its original container and store it in a cool, dry place.
• Do not share your inhaler with others to prevent the spread of infections.
• Regularly clean your inhaler device as per the manufacturer's instructions.