Brufen Plus (20/200mg) 20 Tablets

Ibuprofen 200mg and chlorodine combination works synergistically to provide pain relief and reduce inflammation. Ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), inhibits the production of prostaglandins by blocking the cyclooxygenase (COX) enzymes, particularly COX-1 and COX-2. This action decreases the synthesis of prostaglandins, which are involved in mediating pain, inflammation, and fever. By reducing prostaglandin levels, ibuprofen helps alleviate pain, decrease swelling, and lower body temperature. Chlorodine, on the other hand, is an antihistamine that blocks H1 histamine receptors, preventing the release of histamine and other inflammatory mediators. This action helps reduce itching, sneezing, and other allergic symptoms. Together, ibuprofen and chlorodine provide effective relief from pain, inflammation, and allergic reactions, making them a useful combination for managing various conditions.

Ibuprofen 200mg, chlorodine

NSAID and Antihistamine

Tablet

The following are the uses of Ibuprofen 200mg, chlorodine Tablet:

• Used for relieving mild to moderate pain, such as headaches, toothaches, and period pain.
• Used for reducing inflammation and lowering fever.
• Used to ease symptoms of cold and flu.
• Used for treating minor injuries like sprains and strains.
• Used to manage symptoms of arthritis and joint pain.
• Used for providing temporary relief from minor aches and pains.
• Used as an anti-inflammatory agent to reduce swelling.
• Used under medical advice for short-term pain management.

In the case of an overdose of Ibuprofen 200mg and chlorodine tablets, individuals may experience symptoms such as nausea, vomiting, stomach pain, and in severe cases, kidney damage or gastrointestinal bleeding. Prompt action is vital, including contacting a healthcare professional or poison control center for guidance. Treatment may involve supportive care, gastric decontamination, and managing symptoms until the effects of the overdose subside. It is important to seek assistance promptly to ensure the best possible outcome.

In the case of a missed dose of Ibuprofen 200mg, it is generally safe to take the missed dose as soon as you remember, but if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. For the chloroquine tablet, if you miss a dose, take it as soon as you remember, however, if it is near the time of your next dose, skip the missed dose and resume your regular dosing schedule. It is important to not double the dose to make up for a missed one, and if you miss multiple doses, consult your healthcare provider for guidance.

To take Ibuprofen 200mg and Chlorpheniramine Maleate Tablet, swallow the tablet with a full glass of water, following the dosage instructions provided by your healthcare professional, typically one tablet every 4 to 6 hours as needed, but not exceeding the maximum daily dosage.

Here are the conditions and situations when Ibuprofen 200mg and Chloroquine tablets should not be taken:

• Not suitable for individuals with a known allergy to Ibuprofen, aspirin, or other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Should not be used in patients with a history of stomach bleeding or perforation caused by NSAIDs.
• Contraindicated in individuals with severe heart failure, heart disease, or high blood pressure that is not controlled.
• Not recommended for those who have had or are scheduled for heart bypass surgery.
• Avoid using if you have a history of stomach ulcers or gastrointestinal bleeding.
• Do not take if you have severe kidney or liver disease.
• Should not be used in individuals with a known allergy to Chloroquine or related drugs.
• Contraindicated in patients with known retinal changes or visual field defects.
• Not recommended for long-term use in children due to potential retinal toxicity.
• Avoid using if you have a history of liver disease, severe gastrointestinal disorders, or certain blood disorders (e.g., porphyria).
• Not suitable for individuals with known hypersensitivity to 4-aminoquinoline compounds.
• Do not take if you have a history of seizures or epilepsy.

The side effects may include:

• Stomach pain
• Nausea and vomiting
• Diarrhea
• Dizziness or vertigo
• Headache
• Drowsiness
• Skin rash or itching
• Ringing in the ears (tinnitus)
• Dry mouth
• Drowsiness or fatigue
• Nausea and vomiting
• Constipation
• Blurred vision
• Dizziness
• Restlessness or nervousness

Following are the precautions and warnings for Ibuprofen 200mg and Chlorodine Tablets:

• Ibuprofen should not be used by individuals with a history of allergic reactions to NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) or any other ingredients in the tablet.
• Long-term use of Ibuprofen may lead to gastrointestinal bleeding, especially in the elderly. Regular monitoring is required.
• Not recommended for individuals with active peptic ulcers or a history of gastrointestinal bleeding.
• Patients with cardiovascular risks such as high blood pressure, heart disease, or a history of stroke should use Ibuprofen with caution.
• Chlorodine may cause drowsiness and dizziness, so patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Not suitable for individuals with a history of asthma or those who have experienced severe allergic reactions to other medications.
• Patients with kidney or liver disease should use this medication with caution and under medical supervision.
• Consult a healthcare professional if you are pregnant, planning to become pregnant, or breastfeeding before taking these medications.

Following are the drug interactions for Ibuprofen 200mg and Chlorpheniramine Maleate (assuming Chlorodine refers to Chlorpheniramine):

• Ibuprofen may increase the risk of bleeding when taken with anticoagulants (e.g., warfarin) or antiplatelet drugs (e.g., aspirin).
• NSAIDs like Ibuprofen can reduce the effectiveness of antihypertensive medications, including ACE inhibitors and diuretics.
• Ibuprofen may increase serum lithium levels when used with lithium, requiring monitoring.
• Chlorpheniramine can enhance the sedative effects of CNS depressants (e.g., alcohol, benzodiazepines, opioids).
• Concomitant use of Chlorpheniramine with MAO inhibitors may lead to severe adverse reactions, including hypertension.
• Antihistamines like Chlorpheniramine can potentially reduce the effectiveness of certain antidepressants and antipsychotics.
• Ibuprofen may decrease the elimination of methotrexate, increasing its toxicity.

Following are the food interactions for Ibuprofen 200mg and Chlorodine Tablets:

• Ibuprofen may interact with alcohol, increasing the risk of stomach bleeding and liver damage. Avoid or limit alcohol consumption.
• Ibuprofen may reduce the blood-thinning effects of aspirin, which is commonly used in low doses to prevent heart attacks and strokes.
• Avoid grapefruit and grapefruit juice as they may interfere with Ibuprofen metabolism, potentially increasing drug levels in the body.
• Chlorodine may cause nausea and vomiting; consuming light, easily digestible foods can help manage these symptoms.
• Avoid caffeine-rich foods and beverages as they may increase the stimulant effects of Chlorodine, leading to restlessness and insomnia.
• Consuming a balanced diet rich in fiber can help prevent constipation, a potential side effect of Chlorodine.
• Ensure adequate hydration by drinking plenty of fluids to reduce the risk of Chlorodine-induced dehydration.

Ibuprofen 200mg and Chlorodine tablets should be stored in a cool, dry area at room temperature, ensuring protection from direct sunlight and moisture. Keep the medication securely sealed within its original packaging to maintain its integrity. Avoid bathroom storage or placement near heat-emitting appliances like stoves or radiators, as temperature fluctuations can compromise the medicine's quality. Adhere to the packaging's expiration date, and when disposing of unused or expired tablets, refrain from flushing them or pouring them down the drain. Consult your pharmacist or healthcare provider for appropriate disposal methods, and always keep medication out of children's reach to prevent accidental consumption.

Following are the quick tips for this Tablet:

• Take with or after food to prevent stomach upset.
• Swallow the tablet whole with a glass of water.
• Do not crush or chew the tablet.
• Avoid taking with other NSAIDs or blood thinners.
• Inform your doctor if you have a history of stomach ulcers or kidney problems.
• Take the tablet as directed by your doctor.
• It can be taken with or without food.
• Do not exceed the prescribed dose.
• Store in a cool, dry place, away from direct sunlight.
• Keep out of reach of children and pets.
• Inform your doctor if you have liver or kidney problems.
• Do not take if you are allergic to any of its ingredients.