BRULIDINE CREAM

Dibrompropamidine isetionate, the active ingredient in Dibrompropamidine Isetionate Cream, exerts its antimicrobial effect primarily through interference with DNA synthesis in bacteria and fungi. It binds to the DNA molecule, preventing its replication and inhibiting bacterial and fungal growth. Specifically, dibrompropamidine disrupts the helical structure of DNA, impeding essential cellular processes like transcription and replication, which are crucial for microbial proliferation. This mechanism of action contributes to the cream's effectiveness in treating various skin infections caused by susceptible microorganisms.

Dibrompropamidine isetionate

Antimicrobial cream

Cream

The following are the uses of Dibrompropamidine isetionate Cream:

• Used for the treatment of superficial skin infections caused by bacteria
• Used for impetigo, a highly contagious skin infection
• Used for infected eczema, ensuring the underlying dermatitis is also treated
• Used for infected traumatic lesions, like scratches and bites
• Used for eradicating nasal carriage of Staphylococcus aureus, to prevent infections during surgeries
• Used for preventing infections in minor burns, wounds, and abrasions
• Used for reducing the risk of infection in patients with low immune function
• Used for maintaining skin hygiene in various dermatological conditions

In the case of an overdose of Dibrompropamidine isetionate cream, it is important to remain calm and take appropriate action. Gently wash the affected area with water to remove any excess cream. Do not attempt to induce vomiting, as this product is for external use only. Seek medical advice immediately, and provide the healthcare professional with the product details. They will provide guidance on further treatment and monitor for any potential adverse effects.

In the case of a missed dose of Dibrompropamidine isetionate Cream, it is generally recommended to apply the cream as soon as you remember. However, if it is almost time for your next scheduled dose, simply skip the missed application and continue with your regular schedule. Do not apply extra cream to make up for the missed dose, as this may increase the risk of skin irritation. If you frequently miss doses, it's best to consult your healthcare provider for advice on how to manage your treatment plan effectively.

To apply Dibrompropamidine isetionate Cream, clean and dry the affected skin area, then gently apply a thin layer of the cream, spreading it evenly, and avoid rubbing it vigorously, ensuring complete coverage of the treatment area as directed by your healthcare provider.

Here are the situations when Dibrompropamidine isetionate Cream should not be used:

• Do not use if you are allergic to dibrompropamidine, isetionate, or any other similar medications.
• Avoid using this cream if you have a known sensitivity or reaction to any of its ingredients.
• Not suitable for individuals with severe or widespread skin infections; seek alternative medical treatment.
• Should not be used on open wounds, severe burns, or severely broken skin.
• Avoid contact with eyes, nose, mouth, and other mucous membranes.
• Do not use this cream for conditions other than those specified without medical advice.
• Discontinue use and consult a doctor if irritation, redness, or swelling persists or worsens.

The side effects of Dibrompropamidine isetionate Cream may include:

• Skin irritation at the application site
• Redness or erythema
• Itching (pruritus)
• Dry skin or peeling
• Burning sensation
• Allergic reactions (such as rash, hives, or itching)
• Swelling or edema
• Contact dermatitis (skin inflammation)

Following are the precautions and warnings for Dibrompropamidine isetionate Cream:

• Avoid contact with eyes, nose, and mouth. In case of accidental contact, rinse thoroughly with water.
• This cream is for external use only and should not be ingested or applied to open wounds or mucous membranes.
• Do not use this medication if you are allergic to dibrompropamidine or any other ingredients in the cream.
• If you are using other topical medications, consult your healthcare provider before applying this cream to avoid potential interactions.
• Keep the treated area clean and avoid covering it with airtight dressings or bandages.
• Do not use this cream for prolonged periods without consulting your doctor, especially if symptoms persist or worsen.
• Pregnant and breastfeeding women should consult their healthcare professional before using this medication.
• Store the cream at room temperature, away from direct sunlight and moisture.

Following are the drug interactions for Dibrompropamidine isetionate Cream:

• Dibrompropamidine isetionate may interact with other topical medications, especially those containing silver or mercury, potentially reducing the effectiveness of both agents.
• Topical corticosteroids should be used with caution in combination with Dibrompropamidine isetionate, as they may mask the signs of infection and delay healing.
• Avoid using other antiseptic or disinfectant products simultaneously, as this may cause skin irritation or alter the pH, reducing the efficacy of the medication.
• The cream may interact with systemic medications that affect the immune system, such as immunosuppressants, potentially increasing the risk of infection.
• Concomitant use with radiation therapy or chemotherapy drugs can potentially increase skin sensitivity and should be closely monitored.
• Dibrompropamidine isetionate may interact with topical retinoids, leading to increased skin irritation and dryness.
• Caution is advised when using this medication with other treatments that cause photosensitivity, as it may increase the risk of sunburn.

Following are the food interactions for Dibrompropamidine isetionate Cream:

• Dibrompropamidine isetionate is for external use only, so there are no direct food interactions as it is not ingested.
• However, it is recommended to avoid consuming alcohol during the treatment period, as it may increase skin sensitivity and cause irritation.
• Grapefruit and grapefruit juice should be consumed with caution as they can interfere with the skin's natural barrier function and potentially affect the absorption of the medication.
• Avoid spicy foods, as they can cause skin flushing and exacerbate any skin irritation.
• Dairy products and high-fat foods may not directly interact with the cream, but maintaining a healthy diet supports overall skin health.
• Caffeinated beverages may increase skin sensitivity, so consider reducing coffee and tea intake.
• Some herbal supplements, like St. John's Wort, may increase photosensitivity, so consult a healthcare provider if you're taking any herbal remedies.
• Always follow the instructions provided by your healthcare professional regarding the application of the cream and any specific dietary recommendations.

Dibrompropamidine isetionate cream should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. The cream's original container should be tightly sealed to maintain its integrity and prevent contamination. Avoid storing it in high-temperature areas like bathrooms, kitchens, or near heating devices, as heat can impact its effectiveness. When the cream is no longer needed or has reached its expiration date, it should be disposed of responsibly. Do not dispose of it in wastewater or the trash; instead, consult your local pharmacy or healthcare facility for guidance on safe disposal practices, ensuring that it is kept away from children and pets.

Following are the quick tips for Dibrompropamidine Isetionate Cream:

• Wash your hands before and after applying the cream to maintain hygiene.
• Clean and dry the affected area before applying the cream.
• Apply a thin layer of cream to the affected area as directed by your doctor.
• Gently rub the cream into the skin until it is evenly spread.
• Avoid applying the cream to broken or irritated skin.
• Do not cover the treated area with bandages or tight clothing.
• Store the cream at room temperature, away from direct sunlight and moisture.