Busonide (200/6mcg) 30 Dry Powder Inhaler Capsules

Symbicort 200/6 mcg, which contains budesonide and formoterol, has a specific mechanism of action. Budesonide, a corticosteroid, primarily targets inflammation in the airways by binding to glucocorticoid receptors in respiratory tract cells, suppressing the release of inflammatory mediators and reducing airway responsiveness to allergens and irritants. Formoterol, a long-acting beta-agonist (LABA), stimulates beta-2 adrenoceptors in the airways, leading to smooth muscle relaxation and bronchodilation, which helps to open up constricted airways and improve breathing. The combination of these two medications in Symbicort provides both rapid relief from symptoms and long-term control of inflammation in asthma and chronic obstructive pulmonary disease (COPD).

Bronchodilator/corticosteroid combination.

Capsule

The following are the uses of Symbicort 200mcg, Turbohaler 6mcg Capsule:

• Used for relieving symptoms of asthma and preventing asthma attacks.
• Used for long-term management of chronic obstructive pulmonary disease (COPD).
• Used to reduce inflammation in the airways and open up the lungs, making breathing easier.
• Used as a maintenance treatment to improve lung function over time.
• Used for quick relief of sudden symptoms like coughing, wheezing, or shortness of breath.
• Used to reduce the need for oral corticosteroids in asthma management.
• Used as a preventative measure to reduce the frequency and severity of asthma episodes.

In the case of an overdose of Symbicort 200mcg, Turbohaler 6mcg Capsule, it is important to recognize the signs and act promptly. Symptoms may include rapid heart rate, tremors, anxiety, and potential respiratory issues. If you suspect an overdose, seek medical advice immediately. Treatment involves monitoring vital signs, providing supportive care, and potentially administering specific medications to address any adverse effects. Prompt action can help manage the situation effectively.

In the case of a missed dose of Symbicort 200mcg Turbohaler, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. For the Turbohaler 6mcg Capsule, if you miss a dose, administer it as soon as possible, and then adjust the timing of the next dose accordingly. It is important to maintain a consistent medication routine, but if you miss a dose, consult your healthcare provider for specific guidance on managing missed doses.

To use Symbicort Turbohaler, remove the mouthpiece cover, hold the inhaler upright, and twist the base to load a dose, then breathe out gently, place the mouthpiece in your mouth, and breathe in steadily and deeply through your mouth, finally hold your breath for a few seconds before removing the inhaler and exhaling slowly.

Following are the conditions/situations when Symbicort 200mcg Turbohaler 6mcg Capsule should not be used:

• Do not use if you are allergic to budesonide, formoterol, or any other ingredients in the medication.
• Not suitable for individuals with a history of severe allergic reactions to milk proteins, as the medication contains lactose.
• Contraindicated in patients with a history of paradoxical bronchospasm (worsening of breathing) after using similar medications.
• Should not be used to treat sudden asthma attacks or COPD exacerbations.
• Not recommended for individuals with untreated fungal, bacterial, or viral infections in the respiratory tract.
• Avoid using it if you have a history of heart problems, such as rapid or irregular heartbeat, or severe heart disease.
• Not suitable for individuals with uncontrolled high blood pressure.
• Should not be used in patients with diabetes that is not well-managed.
• Contraindicated during severe medical emergencies or in patients who are in a state of emergency.

The side effects of Symbicort 200mcg, Turbohaler 6mcg Capsule may include:

• Throat irritation or dryness
• Hoarseness or changes in voice
• Cough or increased coughing
• Mouth or throat infections (e.g., oral thrush)
• Headache
• Tremors or shaking
• Palpitations or increased heart rate
• Muscle cramps or spasms
• Immune system suppression (increased susceptibility to infections)

Following are the precautions and warnings for Symbicort 200mcg, Turbohaler 6mcg Capsule:

• This medication is intended for inhalation only and should not be swallowed. Ensure you understand the correct technique for using the Turbohaler device.
• Do not use Symbicort if you are allergic to budesonide, formoterol, or any other ingredients in the medication.
• Inform your doctor if you have a history of heart problems, high blood pressure, diabetes, thyroid issues, or eye diseases such as glaucoma or cataracts.
• Symbicort may cause an increase in blood pressure and heart rate, so regular monitoring is recommended.
• Avoid sudden withdrawal, especially if you have asthma. Gradually reduce the dose under medical supervision.
• Children and adolescents should use Symbicort under close medical supervision.
• Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before using Symbicort.

Following are the drug interactions for Symbicort 200mcg, Turbohaler 6mcg Capsule:

• Beta-blockers (e.g., propranolol) may reduce the bronchodilator effect of formoterol, a component of Symbicort.
• Concomitant use with other long-acting beta-agonists (LABAs) or long-acting muscarinic antagonists (LAMAs) should be avoided due to increased risk of adverse effects.
• Symbicort may interact with xanthine derivatives like theophylline, increasing the risk of side effects such as tremor and palpitations.
• The use of corticosteroids like budesonide with ketoconazole or other strong CYP3A4 inhibitors can lead to increased corticosteroid exposure.
• Macrolide antibiotics (e.g., erythromycin) may inhibit the metabolism of formoterol, potentially leading to increased side effects.
• Non-potassium sparing diuretics (e.g., furosemide) or licorice in large amounts may cause hypokalemia, which may be exacerbated by beta-agonists like formoterol.
• Monitoring is advised when using Symbicort with other medications that prolong the QT interval, as this may increase the risk of arrhythmias.

Following are the food interactions for Symbicort 200mcg, Turbohaler 6mcg Capsule:

• Avoid consuming grapefruit or grapefruit juice as it can increase the concentration of budesonide, one of the active ingredients, in the blood, potentially leading to an increased risk of side effects.
• Caffeine intake should be monitored as it may interact with the medication's effects on the respiratory system, potentially causing increased heart rate or nervousness.
• Limit the consumption of foods high in salt and potassium, as this medication may affect their balance in the body.
• Alcohol can increase the risk of breathing problems and is best avoided or limited while using this medication.
• Dairy products like milk or yogurt can decrease the absorption of the medication, so it's advisable to separate their consumption by a few hours.
• Vitamin D supplements should be used with caution as this medication may increase vitamin D levels in the body.
• Always ensure you follow the dosage instructions provided by your healthcare professional for optimal results.

Symbicort 200mcg, Turbohaler 6mcg Capsule should be stored in a cool and dry place, preferably at room temperature (below 25°C/77°F). Protect the inhaler from direct sunlight, moisture, and extreme heat by keeping it in its original packaging. Do not puncture or incinerate the inhaler, as it contains pressurized gas. Always check the expiration date and do not use the inhaler if it has expired. When the medication is no longer needed or has passed its expiry, it should be disposed of carefully. Contact your local waste management authorities or healthcare provider for guidance on proper disposal methods to ensure it is done in an environmentally friendly manner. Keep the medication out of sight and reach of children and pets to prevent accidental exposure.

Following are the quick tips for Symbicort 200mcg, Turbohaler 6mcg Capsule:

• Consult your doctor before use, especially if you have heart problems or high blood pressure.
• Follow the prescribed dosage and inhalation technique as demonstrated by your healthcare provider.
• Ensure you understand how to use the Turbohaler correctly for effective medication delivery.
• Rinse your mouth after each inhalation to reduce the risk of oral thrush.
• Do not stop using the medication abruptly without consulting your doctor.
• Keep the Turbohaler clean and store it in a dry place at room temperature.
• Regularly check the expiry date and replace the Turbohaler as needed.