Busonide (400/12mcg) 30 Dry Powder Inhaler Capsules

Symbicort 400/12 Turbohaler contains two active substances, budesonide and formoterol fumarate dihydrate. Budesonide is a corticosteroid that reduces inflammation in the lungs, helping to decrease swelling and mucus production in the airways. It also prevents the release of certain substances in the body that can trigger inflammation and asthma symptoms. Formoterol fumarate dihydrate is a long-acting beta-agonist (LABA) that relaxes the smooth muscles surrounding the airways. By stimulating beta-2 receptors in the lungs, formoterol causes the muscles to relax, leading to bronchodilation and improved airflow. This dual action helps to control asthma symptoms by reducing inflammation and opening up the airways, making breathing easier for patients.

Corticosteroid/long-acting beta-agonist.

Capsule

The following are the uses of Symbicort 400mcg, Turbohaler 12mcg Capsule:

• Used for treating asthma in adults and adolescents aged 12 years and above
• Used to prevent symptoms such as shortness of breath, wheezing, and tightness in the chest
• Used for long-term management of chronic obstructive pulmonary disease (COPD)
• Used to reduce inflammation and open up the airways, making breathing easier
• Used as a maintenance treatment to prevent asthma attacks and COPD exacerbations
• Used for quick relief during sudden asthma episodes or 'rescue' medication
• Used to improve lung function and overall breathing capacity

In the case of an overdose of Symbicort 400mcg Turbohaler 12mcg capsules, the primary concern is the potential for an increased risk of respiratory-related side effects. These may include rapid breathing, an elevated heart rate, and an increased risk of respiratory infections. It is important to recognize the signs of an overdose, such as severe headaches, tremors, and chest pain, and seek medical advice promptly. Timely intervention and appropriate medical care can help manage any adverse effects and ensure the patient's well-being.

In the case of a missed dose of Symbicort 400mcg Turbohaler, take the missed dose as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss a dose of the 12mcg capsules, take it as soon as possible, but if it's close to your next dose, skip the missed dose and continue with your regular dosing schedule. It's important not to take extra medication to compensate for a forgotten dose.

To use Symbicort Turbohaler, remove the mouthpiece cover, hold the inhaler away from your face, and press the button while breathing in deeply and slowly through the mouthpiece, then hold your breath for a few seconds before exhaling.

Following are the conditions when Symbicort 400mcg, Turbohaler 12mcg Capsule should not be used:

• Should not be used in individuals with a known allergy to budesonide, formoterol, or any other ingredients in the medication.
• Not suitable for individuals with a history of severe allergic reactions to milk proteins, as the medication may contain small amounts of lactose.
• Contraindicated in patients with untreated or unstable severe heart problems, including rapid or irregular heartbeats.
• Should not be used in individuals with uncontrolled high blood pressure.
• Not recommended for patients with severe or uncontrolled asthma, as it is not a rescue medication.
• Should be avoided in individuals with a recent heart attack, severe heart failure, or unstable angina.
• Not suitable for those with a history of severe and sudden asthma attacks.
• Contraindicated during acute asthma attacks, as it is not a fast-acting reliever medication.

The side effects of Symbicort 400mcg, Turbohaler 12mcg Capsule may include:

• Throat irritation or dryness
• Hoarseness or changes in voice
• Cough or increased coughing
• Mouth or tongue irritation
• Headache or migraine
• Tremors or shaking
• Palpitations or increased heart rate
• Fungal infections of the mouth and throat

Following are the precautions and warnings for Symbicort 400mcg, Turbohaler 12mcg Capsule:

• Do not use this medication if you are allergic to budesonide, formoterol, or any other ingredients in the capsule.
• Patients with a history of asthma, chronic obstructive pulmonary disease (COPD), or other respiratory issues should use this medication with caution and under medical supervision.
• Symbicort may cause paradoxical bronchospasm; if you experience sudden worsening of breathing, stop using it and seek immediate medical attention.
• This medication may cause oral thrush (a fungal infection in the mouth); rinse your mouth with water after each inhalation to help prevent this.
• Avoid spraying this medication into your eyes; if eye contact occurs, rinse thoroughly with water.
• Symbicort may mask the symptoms of infection; if you develop signs of an infection, inform your doctor.
• Diabetic patients should be aware that this medication may increase blood sugar levels.
• Pregnant and breastfeeding women should consult their doctor before using Symbicort, as it may have potential risks for the fetus and infant.

Following are the drug interactions for Symbicort 400mcg, Turbohaler 12mcg Capsule:

• Concurrent use with other long-acting beta-agonists (LABAs) or other medications containing LABA components is not recommended due to the increased risk of asthma-related death.
• Beta-blockers, including eye drops, can reduce the effectiveness of budesonide/formoterol and may lead to severe asthma exacerbations.
• Using Symbicort with other corticosteroids may increase the risk of systemic corticosteroid side effects.
• Caution is advised when combining with non-potassium-sparing diuretics, as it may lead to hypokalemia.
• Antifungal medications like ketoconazole can increase the exposure to budesonide and formoterol, potentially enhancing their effects.
• MAO inhibitors may interact with Symbicort, potentially increasing the risk of cardiovascular side effects.
• Theophylline levels may be affected by Symbicort, requiring monitoring and dose adjustments.

Following are the food interactions for Symbicort 400mcg, Turbohaler 12mcg Capsule:

• Avoid consuming high-fat meals as they may increase the absorption of budesonide, a component of Symbicort, which can lead to increased side effects.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of the medication, potentially altering its effectiveness.
• Caffeine-rich foods and beverages should be limited as they may increase the stimulatory effects of formoterol, another component of Symbicort, leading to increased heart rate and blood pressure.
• Avoid alcohol consumption as it can enhance the sedative effects of the medication and increase the risk of respiratory depression.
• Dairy products, such as milk and yogurt, can potentially interfere with the absorption of budesonide, so it is best to take Symbicort at least 2 hours before or after consuming dairy.
• Avoid eating large quantities of cruciferous vegetables like broccoli and cauliflower, as they may slightly alter the metabolism of the medication.
• Maintain a balanced diet and ensure adequate fluid intake to support overall respiratory health while using Symbicort.
• There are no specific food restrictions, but it's advisable to consult your healthcare provider for personalized dietary advice based on your medical condition.

Symbicort 400mcg, Turbohaler 12mcg Capsule should be stored in a cool and dry place, preferably at room temperature (below 25°C). Keep the medication in its original packaging, away from direct sunlight, heat, and moisture to maintain its effectiveness. It is crucial not to puncture or incinerate the inhaler and always check the expiry date before use. When disposing of the medication, do not throw it into the trash or pour it down the drain. Instead, follow local guidelines or consult a healthcare professional for proper disposal methods to ensure environmental safety. Keep the medication out of the reach of children and pets to prevent accidental exposure.

Following are the quick tips for Symbicort 400mcg and Turbohaler 12mcg Capsule:

• Ensure you receive proper training on how to use the inhaler device from your healthcare provider.
• Shake the inhaler well before each use to ensure proper medication delivery.
• Inhale the medication deeply and slowly to ensure it reaches your lungs effectively.
• Keep a track of your remaining doses and get a refill before running out of medication.
• Store the inhaler at room temperature, away from direct sunlight and moisture.
• Clean the inhaler device regularly as instructed to maintain its effectiveness.
• Always carry your medication with you, especially when traveling, to ensure consistent treatment.