Caborin (135mg) 30 Tablets

Mebeverine 135mg Tablet primarily exerts its therapeutic effects through its action on smooth muscle cells in the gastrointestinal tract. Its mechanism of action involves blocking calcium channels in smooth muscle cells, leading to relaxation of the intestinal muscles. This calcium channel blockade reduces the influx of calcium ions into the muscle cells, which subsequently inhibits muscle contractions. By relaxing the smooth muscles in the gastrointestinal tract, Mebeverine alleviates abdominal pain and discomfort associated with gastrointestinal spasms and cramps. This mechanism of action makes Mebeverine particularly effective in managing conditions like irritable bowel syndrome (IBS) and other gastrointestinal disorders characterized by excessive intestinal motility and spasmodic activity.

Mebeverine 135mg

Anticholinergic antispasmodic.

Tablet

The following are the uses of Mebeverine 135mg Tablet:

• Used for relieving painful muscle spasms in the intestines, particularly in conditions like irritable bowel syndrome (IBS).
• Used to alleviate abdominal pain, discomfort, and cramping.
• Used to relax the muscles in the digestive tract, easing digestion and reducing pain.
• Used to manage symptoms of intestinal hypermotility, where the intestines contract too frequently.
• Used to improve symptoms of diarrhea and bowel urgency.
• Used to treat symptoms of non-specific colitis, reducing inflammation and pain.
• Used for the short-term treatment of bowel symptoms related to anxiety or stress.

In the case of an overdose of Mebeverine 135mg Tablets, it is important to remain calm and seek medical advice promptly. Symptoms of an overdose may include drowsiness, dizziness, and blurred vision. If you suspect an overdose, contact a healthcare professional or a poison control center for guidance. They will provide specific instructions based on the individual's condition, which may include inducing vomiting or administering activated charcoal to prevent further absorption of the medication. Timely action can help mitigate potential adverse effects.

In the case of a missed dose of Mebeverine 135mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you've missed multiple doses, contact your healthcare provider for guidance on how to safely resume your medication. It's best to establish a routine to help you remember to take your medication as prescribed to ensure maximum effectiveness.

To take Mebeverine 135mg Tablet, swallow the tablet whole with a glass of water, following the prescribed dosage as directed by your healthcare professional, usually taken three times a day, with or without food.

Following are the conditions when Mebeverine 135mg Tablet should not be used:

• Do not take if you have a known allergy to Mebeverine or any of its ingredients.
• Avoid if you have a gastrointestinal obstruction or severe gastrointestinal conditions, such as ulcerative colitis, as it may worsen these conditions.
• Not recommended for individuals with severe kidney or liver disease, as the medication may not be properly metabolized.
• Contraindicated in individuals with a history of hypersensitivity reactions to anti-cholinergic medications.
• Do not use if you have a history of porphyria, as it may trigger an attack.
• Should not be used in patients with rare hereditary problems of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.

The side effects of Mebeverine 135mg Tablet may include:

• Dry mouth
• Dizziness
• Headache
• Nausea
• Stomach pain
• Diarrhea
• Skin rash
• Allergic reactions (rarely)

Following are the precautions and warnings for Mebeverine 135mg Tablet:

• Not suitable for individuals with known allergies to Mebeverine or other similar medications; an alternative treatment should be considered.
• Patients with kidney or liver disease should use with caution and under medical supervision, as dosage adjustments might be necessary.
• Elderly patients may be more sensitive to the effects of Mebeverine, so a lower dosage is recommended initially.
• Avoid alcohol consumption while taking this medication, as it may enhance the sedative effects.
• Mebeverine may cause dizziness or sleepiness; patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Not recommended for children below 12 years of age unless prescribed by a doctor.
• Consult a doctor before taking Mebeverine if you are pregnant, planning to become pregnant, or breastfeeding.

Following are the drug interactions for Mebeverine 135mg Tablet:

• Mebeverine may interact with anticholinergic medications, leading to increased side effects such as dry mouth, constipation, and blurred vision.
• The effects of Mebeverine can be reduced by medications that stimulate the gut, including laxatives and prokinetics.
• It may increase the absorption of digoxin, requiring close monitoring of digoxin levels.
• Mebeverine can enhance the sedative effects of central nervous system depressants like opioids and benzodiazepines.
• When taken with certain antibiotics, Mebeverine may affect their absorption, potentially reducing their effectiveness.
• Caution is advised when combining Mebeverine with medications that affect liver enzymes, as this may alter its metabolism.
• It may also interact with antacids, reducing the absorption of both drugs if taken together.

Following are the food interactions for Mebeverine 135mg Tablet:

• Mebeverine can interact with high-fat meals, slowing down its absorption and potentially reducing its effectiveness. It is best to take the medication on an empty stomach or as directed by your doctor.
• Grapefruit and grapefruit juice should be consumed with caution as they may interfere with the metabolism of Mebeverine, leading to increased drug levels in the body and potential side effects.
• Alcohol consumption should be limited or avoided as it can increase the sedative effects of Mebeverine, causing enhanced drowsiness and dizziness.
• Avoid caffeine-rich foods and beverages, as they may counteract the relaxing effect of Mebeverine on smooth muscles.
• Spicy foods may exacerbate gastrointestinal symptoms, so it is advisable to minimize their intake while taking Mebeverine.
• A balanced diet rich in fiber can complement Mebeverine's action by promoting healthy digestion and reducing gastrointestinal discomfort.
• Stay well-hydrated by drinking adequate water to support the medication's effectiveness and overall digestive health.
• Certain herbal teas, like peppermint or chamomile, may have soothing effects on the digestive system and can be considered alongside Mebeverine, but consult with a healthcare professional for personalized advice.

Mebeverine 135mg Tablets should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from direct sunlight and moisture. The original packaging should be tightly sealed to maintain its integrity and prevent contamination. Avoid storing the tablets in bathrooms or near heat-emitting appliances to maintain their effectiveness. Always check the expiration date, and if the medication is no longer needed or has expired, proper disposal is crucial. Consult your pharmacist for guidance on safe disposal methods, and keep the medication away from children to prevent accidental consumption. It is essential to follow these storage and disposal guidelines to maintain the quality and safety of Mebeverine tablets.

Following are the quick tips for Mebeverine 135mg Tablet:

• Consult your doctor before taking this medication, especially if you have underlying health conditions.
• Take the tablet as directed by your healthcare professional.
• It can be taken with or without food, but taking it with food may reduce stomach-related side effects.
• Ensure you complete the full prescribed course, even if you feel better earlier.
• Avoid crushing or chewing the tablet; swallow it whole with water.
• Store the medication in a cool, dry place, away from direct sunlight and moisture.
• Inform your doctor about all medications you are currently taking to avoid potential interactions.