CAC 1000 SYP 120ML

Calcium gluconate, when administered, acts as a calcium supplement, primarily by replenishing and maintaining optimal calcium levels in the body. Its mechanism involves binding to specific calcium receptors and channels in various tissues, such as the skeletal and cardiac muscles, nerves, and blood vessels. Calcium gluconate facilitates calcium-dependent physiological processes, including muscle contraction, nerve impulse transmission, blood clotting, and the maintenance of bone health. By providing calcium ions, it helps regulate cellular functions, supports enzyme activity, and contributes to the structural integrity of bones and teeth. This action is crucial in preventing and managing conditions related to calcium deficiency, ensuring the proper functioning of calcium-dependent systems throughout the body.

Calcium gluconate

Calcium salt.

Suspension

The following are the uses of Calcium gluconate Syrup/Suspension:

• Used for treating calcium deficiencies and conditions like hypocalcemia and hypoparathyroidism
• Used for managing high levels of potassium in the blood (hyperkalemia)
• Used as an antidote for magnesium sulfate overdose
• Used for cardiac health, helping to manage irregular heartbeats and support cardiac function
• Used to reduce the toxicity of certain medications like cardiac glycosides
• Used to improve bone health and prevent bone-related disorders
• Used to aid in the absorption of other minerals and vitamins, particularly Vitamin D

In the case of an overdose of Calcium Gluconate Syrup/Suspension, the primary concern is hypercalcemia, leading to symptoms like nausea, vomiting, constipation, and increased urination. Severe cases may result in cardiac arrhythmias, confusion, and even coma. Prompt medical intervention is vital, focusing on supportive care and managing calcium levels. The treatment strategy may include intravenous fluids, diuretics, and in severe instances, dialysis to restore normal calcium concentrations.

In the case of a missed dose of Calcium gluconate Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for advice on how to safely resume your medication regimen. It is recommended to store the medication at room temperature and away from direct sunlight.

To administer Calcium Gluconate Syrup/Suspension, shake the bottle well, measure the prescribed dose with an oral syringe or a measuring cup, and take it orally, following the dosage instructions provided by your healthcare professional, which may vary based on your age and medical condition.

Here are the circumstances when Calcium Gluconate Syrup/Suspension should not be administered:

• Avoid use in patients with a known allergy or hypersensitivity to calcium gluconate or any of its excipients.
• Not suitable for patients with hypercalcemia (high blood calcium levels) or conditions that cause calcium retention.
• Contraindicated in patients with kidney stones or conditions that increase the risk of kidney stone formation.
• Should not be used in patients with severe kidney disease or impaired kidney function.
• Avoid use in patients with heart block or other cardiac conduction disorders.
• Not recommended for patients with a history of calcium-based kidney deposits or calcification of tissues.
• Contraindicated in patients with a known allergy to other calcium salts or calcium-containing products.
• Should not be administered intravenously in conditions where rapid changes in blood calcium levels could be dangerous.

The side effects of Calcium Gluconate Syrup/Suspension may include:

• Nausea and vomiting
• Constipation
• Dry mouth
• Increased thirst
• Abdominal pain
• Allergic reactions (skin rash, itching, swelling)
• Confusion or mental changes
• Fatigue and muscle weakness

Following are the precautions and warnings for Calcium Gluconate Syrup/Suspension:

• Avoid using Calcium Gluconate if you are allergic to any of its ingredients, and seek medical attention if an allergic reaction occurs.
• Use with caution in patients with kidney stones or a history of kidney disease, as it may increase the risk of calcium-related complications.
• This medication should be administered slowly, especially in elderly patients or those with cardiac disease, to prevent potential cardiac side effects.
• Monitor calcium levels regularly during prolonged use to prevent calcium overload.
• Not recommended for intravenous use due to the risk of tissue irritation and calcium salt precipitation.
• Consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding, as Calcium Gluconate may affect fetal bone development.
• Keep out of reach of children. Accidental overdose may lead to severe health consequences.
• Store the medication properly and check the expiration date before use.

Following are the drug interactions for Calcium Gluconate Syrup/Suspension:

• Thiazide diuretics, such as hydrochlorothiazide, may reduce the excretion of calcium, leading to higher calcium levels in the body.
• Anticonvulsants like phenytoin can decrease calcium gluconate absorption, potentially reducing its effectiveness.
• Bisphosphonates, used for osteoporosis, may have decreased absorption when taken with calcium gluconate. Separate dosing is recommended.
• Calcium channel blockers, including verapamil and diltiazem, may have their effects enhanced by calcium gluconate, requiring close monitoring.
• Tetracycline antibiotics should not be taken simultaneously with calcium gluconate, as calcium can interfere with their absorption.
• Calcium gluconate may decrease the absorption of oral iron supplements, so separate administration by several hours is advised.
• Corticosteroids, such as prednisone, can increase calcium excretion, potentially reducing the efficacy of calcium gluconate.

Following are the food interactions for Calcium gluconate Syrup/Suspension:

• High-fiber foods like whole grains, legumes, and certain vegetables can reduce the absorption of Calcium gluconate. It is best to space out calcium intake from these foods.
• Oxalate-rich foods such as spinach, rhubarb, and certain nuts can bind with calcium and reduce its absorption. Avoid consuming these foods within a few hours of taking the medication.
• Phytic acid found in whole grains, legumes, and seeds can also decrease calcium absorption. Consider limiting these foods around medication timing.
• Calcium supplements, including Calcium gluconate, are best absorbed when taken with meals, as the stomach acid aids in calcium absorption.
• Avoid excessive consumption of caffeine as it may lead to increased calcium excretion, reducing the effectiveness of the medication.
• Dairy products are rich in calcium, and consuming them along with Calcium gluconate may increase the total calcium intake, potentially causing side effects.
• Phosphorus-rich foods such as red meat, organ meats, and certain carbonated beverages can affect calcium balance in the body, so moderation is advised.
• Maintaining a balanced diet with a variety of foods is essential while taking Calcium gluconate to ensure optimal absorption and avoid potential interactions.

Calcium gluconate syrup/suspension should be stored in a cool, dry area, preferably at room temperature between 15-25°C (59-77°F). Protect it from light and moisture by keeping it in its original container with the cap tightly sealed. Avoid exposing the medication to extreme temperatures, including freezing or direct sunlight. Always check the expiration date, and never use the syrup/suspension if it has expired. When it's time to discard the medication, do not pour it down the drain or flush it; instead, follow local guidelines for pharmaceutical waste disposal or consult a healthcare professional for advice on safe disposal practices. Keep the syrup/suspension out of children's reach to prevent accidental consumption.

Following are the quick tips for Calcium Gluconate Syrup/Suspension:

• Consult a healthcare professional for the correct dosage and duration of treatment.
• Shake the bottle well before each use to ensure proper mixing.
• Administer the syrup orally, following the prescribed dosage instructions.
• Measure the dose accurately using a calibrated measuring device.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Do not freeze the medication, as it may affect its potency.
• Regularly monitor calcium levels during prolonged use.
• Ensure you complete the full course of treatment as prescribed.